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Murcko scaffold

Ring system with 4 rings and 20 atoms

7 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
7
With full pages
0
Scaffold SMILES

O=C1c2ccccc2C(=O)c2cc3c(cc21)C=CCC3

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1c2ccccc2C(=O)c2cc3c(cc21)C=CCC3

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

Monoanhydroaklavinone chemical structure, C22H18O7, CAS 96886-78-1
Monoanhydroaklavinone
CAS 96886-78-1C22H18O7
Resomycin B chemical structure, C21H16O6, CAS 680610-38-2
Resomycin B
CAS 680610-38-2C21H16O6
9-Ethyl-4,6-dimethoxy-7,8-dihydrotetracene-5,12-dione chemical structure, C22H20O4, CAS 78757-88-7
9-Ethyl-4,6-dimethoxy-7,8-dihydrotetracene-5,12-dione
CAS 78757-88-7C22H20O4
4,6,11-Trimethoxy-7,8-dihydrotetracene-5,12-dione chemical structure, C21H18O5, CAS 77199-86-1
4,6,11-Trimethoxy-7,8-dihydrotetracene-5,12-dione
CAS 77199-86-1C21H18O5
9-Acetyl-6,11-dihydroxy-7,8-dihydrotetracene-5,12-dione chemical structure, C20H14O5, CAS 86309-13-9
9-Acetyl-6,11-dihydroxy-7,8-dihydrotetracene-5,12-dione
CAS 86309-13-9C20H14O5
9-Ethyl-4,6,11-trihydroxy-7,8-dihydrotetracene-5,12-dione chemical structure, C20H16O5, CAS 63605-06-1
9-Ethyl-4,6,11-trihydroxy-7,8-dihydrotetracene-5,12-dione
CAS 63605-06-1C20H16O5
(7S)-6,7,11-Trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-7,8-dihydrotetracene-5,12-dione chemical structure, C21H16O8, CAS 80948-70-5
(7S)-6,7,11-Trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-7,8-dihydrotetracene-5,12-dione
CAS 80948-70-5C21H16O8