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Murcko scaffold

Ring system with 3 rings and 26 atoms

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
26
Chemicals
14
With full pages
1
Scaffold SMILES

O=C(COc1ccccc1)NCCCN1CCN(c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccccc1)NCCCN1CCN(c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

Acetamide, N-(3-(4-phenyl-1-piperazinyl)propyl)-2-(3,4,5-trimethoxyphenoxy)-, dihydrochloride chemical structure, C24H35Cl2N3O5, CAS 65876-21-3
Acetamide, N-(3-(4-phenyl-1-piperazinyl)propyl)-2-(3,4,5-trimethoxyphenoxy)-, dihydrochloride
CAS 65876-21-3C24H35Cl2N3O5
Acetamide, N-(3-(4-(2-methylphenyl)-1-piperazinyl)propyl)-2-(3,4,5-trimethoxyphenoxy)-, dihydrochloride chemical structure, C25H37Cl2N3O5, CAS 65876-22-4
Acetamide, N-(3-(4-(2-methylphenyl)-1-piperazinyl)propyl)-2-(3,4,5-trimethoxyphenoxy)-, dihydrochloride
CAS 65876-22-4C25H37Cl2N3O5
Acetamide, 2-(4-bromo-3,5-dimethylphenoxy)-N-(3-(4-(2-methylphenyl)-1-piperazinyl)propyl)-, dihydrochloride chemical structure, C24H34BrCl2N3O2, CAS 86745-95-1
Acetamide, 2-(4-bromo-3,5-dimethylphenoxy)-N-(3-(4-(2-methylphenyl)-1-piperazinyl)propyl)-, dihydrochloride
CAS 86745-95-1C24H34BrCl2N3O2
Acetamide, N-(3-(4-(2-methylphenyl)-1-piperazinyl)propyl)-2-(2,4,5-trichlorophenoxy)-, monohydrochloride chemical structure, C22H27Cl4N3O2, CAS 86746-07-8
Acetamide, N-(3-(4-(2-methylphenyl)-1-piperazinyl)propyl)-2-(2,4,5-trichlorophenoxy)-, monohydrochloride
CAS 86746-07-8C22H27Cl4N3O2
Acetamide, N-(3-(4-(2-methylphenyl)-1-piperazinyl)propyl)-2-(2,4,6-trimethylphenoxy)-, hydrochloride, hydrate (1:2:1) chemical structure, C25H37Cl2N3O2, CAS 86746-08-9
Acetamide, N-(3-(4-(2-methylphenyl)-1-piperazinyl)propyl)-2-(2,4,6-trimethylphenoxy)-, hydrochloride, hydrate (1:2:1)
CAS 86746-08-9C25H37Cl2N3O2
2-(4-Chlorophenoxy)-N-[3-(4-phenylpiperazin-1-yl)propyl]acetamide chemical structure, C21H26ClN3O2, CAS 913527-52-3
2-(4-Chlorophenoxy)-N-[3-(4-phenylpiperazin-1-yl)propyl]acetamide
CAS 913527-52-3C21H26ClN3O2
2-(4-Chlorophenoxy)-2-methyl-N-[3-(4-phenylpiperazin-1-yl)propyl]propanamide chemical structure, C23H30ClN3O2, CAS 1209446-09-2
2-(4-Chlorophenoxy)-2-methyl-N-[3-(4-phenylpiperazin-1-yl)propyl]propanamide
CAS 1209446-09-2C23H30ClN3O2
N-(3-(4-Phenylpiperazin-1-yl)propyl)-2-(o-tolyloxy)acetamide chemical structure, C22H29N3O2, CAS 1049375-34-9
N-(3-(4-Phenylpiperazin-1-yl)propyl)-2-(o-tolyloxy)acetamide
CAS 1049375-34-9C22H29N3O2
N-(3-(4-Phenylpiperazin-1-yl)propyl)-2-(m-tolyloxy)acetamide chemical structure, C22H29N3O2, CAS 1049475-24-2
N-(3-(4-Phenylpiperazin-1-yl)propyl)-2-(m-tolyloxy)acetamide
CAS 1049475-24-2C22H29N3O2
2-(2-Fluorophenoxy)-N-(3-(4-phenylpiperazin-1-yl)propyl)acetamide chemical structure, C21H26FN3O2, CAS 1049375-41-8
2-(2-Fluorophenoxy)-N-(3-(4-phenylpiperazin-1-yl)propyl)acetamide
CAS 1049375-41-8C21H26FN3O2
2-(4-Fluorophenoxy)-N-[3-(4-phenylpiperazin-1-yl)propyl]acetamide chemical structure, C21H26FN3O2, CAS 1049475-31-1
2-(4-Fluorophenoxy)-N-[3-(4-phenylpiperazin-1-yl)propyl]acetamide
CAS 1049475-31-1C21H26FN3O2
2-(2-Methoxyphenoxy)-N-[3-(4-phenylpiperazin-1-yl)propyl]acetamide chemical structure, C22H29N3O3, CAS 1049396-86-2
2-(2-Methoxyphenoxy)-N-[3-(4-phenylpiperazin-1-yl)propyl]acetamide
CAS 1049396-86-2C22H29N3O3
2-(3-Methoxyphenoxy)-N-[3-(4-phenylpiperazin-1-yl)propyl]acetamide chemical structure, C22H29N3O3, CAS 1049375-48-5
2-(3-Methoxyphenoxy)-N-[3-(4-phenylpiperazin-1-yl)propyl]acetamide
CAS 1049375-48-5C22H29N3O3
2-(4-Methoxyphenoxy)-N-[3-(4-phenylpiperazin-1-yl)propyl]acetamide chemical structure, C22H29N3O3, CAS 1049475-38-8
2-(4-Methoxyphenoxy)-N-[3-(4-phenylpiperazin-1-yl)propyl]acetamide
CAS 1049475-38-8C22H29N3O3