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Murcko scaffold

2-Phenoxy-N-(2-((4-phenylpiperazin-1-yl)sulfonyl)ethyl)acetamide scaffold

55 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
28
Chemicals
55
With full pages
9
Scaffold SMILES

O=C(COc1ccccc1)NCCS(=O)(=O)N1CCN(c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Phenoxy-N-(2-((4-phenylpiperazin-1-yl)sulfonyl)ethyl)acetamide page
Murcko scaffold O=C(COc1ccccc1)NCCS(=O)(=O)N1CCN(c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 55 chemicals

N-[2-[4-(2-Fluorophenyl)piperazin-1-yl]sulfonylethyl]-2-phenoxyacetamide chemical structure, C20H24FN3O4S, CAS 897613-68-2
N-[2-[4-(2-Fluorophenyl)piperazin-1-yl]sulfonylethyl]-2-phenoxyacetamide
CAS 897613-68-2C20H24FN3O4S
2-Phenoxy-N-(2-((4-phenylpiperazin-1-yl)sulfonyl)ethyl)acetamide chemical structure, C20H25N3O4S, CAS 897621-39-5
2-Phenoxy-N-(2-((4-phenylpiperazin-1-yl)sulfonyl)ethyl)acetamide
CAS 897621-39-5C20H25N3O4S
N-(2-((4-Phenylpiperazin-1-yl)sulfonyl)ethyl)-2-(m-tolyloxy)acetamide chemical structure, C21H27N3O4S, CAS 897621-55-5
N-(2-((4-Phenylpiperazin-1-yl)sulfonyl)ethyl)-2-(m-tolyloxy)acetamide
CAS 897621-55-5C21H27N3O4S
2-(2-Fluorophenoxy)-N-[2-(4-phenylpiperazin-1-yl)sulfonylethyl]acetamide chemical structure, C20H24FN3O4S, CAS 897621-61-3
2-(2-Fluorophenoxy)-N-[2-(4-phenylpiperazin-1-yl)sulfonylethyl]acetamide
CAS 897621-61-3C20H24FN3O4S
2-(4-Fluorophenoxy)-N-[2-(4-phenylpiperazin-1-yl)sulfonylethyl]acetamide chemical structure, C20H24FN3O4S, CAS 897621-63-5
2-(4-Fluorophenoxy)-N-[2-(4-phenylpiperazin-1-yl)sulfonylethyl]acetamide
CAS 897621-63-5C20H24FN3O4S
N-(2-((4-(3-Chlorophenyl)piperazin-1-yl)sulfonyl)ethyl)-2-(4-methoxyphenoxy)acetamide chemical structure, C21H26ClN3O5S, CAS 904826-80-8
N-(2-((4-(3-Chlorophenyl)piperazin-1-yl)sulfonyl)ethyl)-2-(4-methoxyphenoxy)acetamide
CAS 904826-80-8C21H26ClN3O5S
N-(2-((4-(4-Methoxyphenyl)piperazin-1-yl)sulfonyl)ethyl)-2-(o-tolyloxy)acetamide chemical structure, C22H29N3O5S, CAS 897610-77-4
N-(2-((4-(4-Methoxyphenyl)piperazin-1-yl)sulfonyl)ethyl)-2-(o-tolyloxy)acetamide
CAS 897610-77-4C22H29N3O5S
N-(2-((4-(4-Methoxyphenyl)piperazin-1-yl)sulfonyl)ethyl)-2-(m-tolyloxy)acetamide chemical structure, C22H29N3O5S, CAS 897610-78-5
N-(2-((4-(4-Methoxyphenyl)piperazin-1-yl)sulfonyl)ethyl)-2-(m-tolyloxy)acetamide
CAS 897610-78-5C22H29N3O5S
N-(2-((4-(4-Methoxyphenyl)piperazin-1-yl)sulfonyl)ethyl)-2-(p-tolyloxy)acetamide chemical structure, C22H29N3O5S, CAS 897610-79-6
N-(2-((4-(4-Methoxyphenyl)piperazin-1-yl)sulfonyl)ethyl)-2-(p-tolyloxy)acetamide
CAS 897610-79-6C22H29N3O5S
N-(2-((4-(2-Methoxyphenyl)piperazin-1-yl)sulfonyl)ethyl)-2-phenoxypropanamide chemical structure, C22H29N3O5S, CAS 897611-30-2
N-(2-((4-(2-Methoxyphenyl)piperazin-1-yl)sulfonyl)ethyl)-2-phenoxypropanamide
CAS 897611-30-2C22H29N3O5S
N-(2-((4-(2-Methoxyphenyl)piperazin-1-yl)sulfonyl)ethyl)-2-(o-tolyloxy)acetamide chemical structure, C22H29N3O5S, CAS 897611-32-4
N-(2-((4-(2-Methoxyphenyl)piperazin-1-yl)sulfonyl)ethyl)-2-(o-tolyloxy)acetamide
CAS 897611-32-4C22H29N3O5S
N-(2-((4-Phenylpiperazin-1-yl)sulfonyl)ethyl)-2-(p-tolyloxy)acetamide chemical structure, C21H27N3O4S, CAS 897621-57-7
N-(2-((4-Phenylpiperazin-1-yl)sulfonyl)ethyl)-2-(p-tolyloxy)acetamide
CAS 897621-57-7C21H27N3O4S
N-(2-{[4-(3-Chlorophenyl)piperazin-1-yl]sulfonyl}ethyl)-2-phenoxyacetamide chemical structure, C20H24ClN3O4S, CAS 897613-09-1
N-(2-{[4-(3-Chlorophenyl)piperazin-1-yl]sulfonyl}ethyl)-2-phenoxyacetamide
CAS 897613-09-1C20H24ClN3O4S
N-(2-((4-(2-Fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)-2-phenoxypropanamide chemical structure, C21H26FN3O4S, CAS 897613-69-3
N-(2-((4-(2-Fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)-2-phenoxypropanamide
CAS 897613-69-3C21H26FN3O4S
N-(2-((4-(2-Fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)-2-(o-tolyloxy)acetamide chemical structure, C21H26FN3O4S, CAS 897613-70-6
N-(2-((4-(2-Fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)-2-(o-tolyloxy)acetamide
CAS 897613-70-6C21H26FN3O4S
N-(2-((4-(2-Fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)-2-(m-tolyloxy)acetamide chemical structure, C21H26FN3O4S, CAS 897618-22-3
N-(2-((4-(2-Fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)-2-(m-tolyloxy)acetamide
CAS 897618-22-3C21H26FN3O4S
N-(2-((4-(2-Fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)-2-(p-tolyloxy)acetamide chemical structure, C21H26FN3O4S, CAS 897618-23-4
N-(2-((4-(2-Fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)-2-(p-tolyloxy)acetamide
CAS 897618-23-4C21H26FN3O4S
2-(2-Fluorophenoxy)-N-(2-{[4-(2-fluorophenyl)piperazin-1-yl]sulfonyl}ethyl)acetamide chemical structure, C20H23F2N3O4S, CAS 897618-24-5
2-(2-Fluorophenoxy)-N-(2-{[4-(2-fluorophenyl)piperazin-1-yl]sulfonyl}ethyl)acetamide
CAS 897618-24-5C20H23F2N3O4S
2-(4-Fluorophenoxy)-N-(2-((4-(2-fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)acetamide chemical structure, C20H23F2N3O4S, CAS 897618-25-6
2-(4-Fluorophenoxy)-N-(2-((4-(2-fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)acetamide
CAS 897618-25-6C20H23F2N3O4S
N-(2-((4-(4-Fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)-2-phenoxypropanamide chemical structure, C21H26FN3O4S, CAS 897618-82-5
N-(2-((4-(4-Fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)-2-phenoxypropanamide
CAS 897618-82-5C21H26FN3O4S
N-(2-((4-(4-Fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)-2-(o-tolyloxy)acetamide chemical structure, C21H26FN3O4S, CAS 897618-83-6
N-(2-((4-(4-Fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)-2-(o-tolyloxy)acetamide
CAS 897618-83-6C21H26FN3O4S
2-(2-Fluorophenoxy)-N-(2-((4-(4-fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)acetamide chemical structure, C20H23F2N3O4S, CAS 897618-86-9
2-(2-Fluorophenoxy)-N-(2-((4-(4-fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)acetamide
CAS 897618-86-9C20H23F2N3O4S
N-(2-((4-(4-Methoxyphenyl)piperazin-1-yl)sulfonyl)ethyl)-2-phenoxyacetamide chemical structure, C21H27N3O5S, CAS 897610-75-2
N-(2-((4-(4-Methoxyphenyl)piperazin-1-yl)sulfonyl)ethyl)-2-phenoxyacetamide
CAS 897610-75-2C21H27N3O5S
N-(2-{[4-(2-Methoxyphenyl)piperazin-1-yl]sulfonyl}ethyl)-2-phenoxyacetamide chemical structure, C21H27N3O5S, CAS 897611-28-8
N-(2-{[4-(2-Methoxyphenyl)piperazin-1-yl]sulfonyl}ethyl)-2-phenoxyacetamide
CAS 897611-28-8C21H27N3O5S