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Murcko scaffold

Ring system with 2 rings and 20 atoms

13 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
20
Chemicals
13
With full pages
6
Scaffold SMILES

O=C(COc1ccccc1)NC(=S)Nc1ccccn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccccc1)NC(=S)Nc1ccccn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

N-[(5-Chloropyridin-2-yl)carbamothioyl]-2-(4-methylphenoxy)acetamide chemical structure, C15H14ClN3O2S, CAS 381204-02-0
N-[(5-Chloropyridin-2-yl)carbamothioyl]-2-(4-methylphenoxy)acetamide
CAS 381204-02-0C15H14ClN3O2S
2-(4-Bromo-2-chlorophenoxy)-N-(pyridin-2-ylcarbamothioyl)acetamide chemical structure, C14H11BrClN3O2S, CAS 649564-89-6
2-(4-Bromo-2-chlorophenoxy)-N-(pyridin-2-ylcarbamothioyl)acetamide
CAS 649564-89-6C14H11BrClN3O2S
N-[(5-Bromopyridin-2-yl)carbamothioyl]-2-(3,4-dimethylphenoxy)acetamide chemical structure, C16H16BrN3O2S, CAS 445412-45-3
N-[(5-Bromopyridin-2-yl)carbamothioyl]-2-(3,4-dimethylphenoxy)acetamide
CAS 445412-45-3C16H16BrN3O2S
N-(5-Iodo-6-methyl-2-pyridinyl)-N'-[(2-methylphenoxy)acetyl]thiourea chemical structure, C16H16IN3O2S, CAS 832680-15-6
N-(5-Iodo-6-methyl-2-pyridinyl)-N'-[(2-methylphenoxy)acetyl]thiourea
CAS 832680-15-6C16H16IN3O2S
N-[(5-Bromo-6-methylpyridin-2-yl)carbamothioyl]-2-(2-methylphenoxy)acetamide chemical structure, C16H16BrN3O2S, CAS 689750-78-5
N-[(5-Bromo-6-methylpyridin-2-yl)carbamothioyl]-2-(2-methylphenoxy)acetamide
CAS 689750-78-5C16H16BrN3O2S
N-[(5-Bromo-6-methylpyridin-2-yl)carbamothioyl]-2-(4-ethylphenoxy)acetamide chemical structure, C17H18BrN3O2S, CAS 638143-61-0
N-[(5-Bromo-6-methylpyridin-2-yl)carbamothioyl]-2-(4-ethylphenoxy)acetamide
CAS 638143-61-0C17H18BrN3O2S
2-(4-Chlorophenoxy)-N-[(5-iodopyridin-2-yl)carbamothioyl]acetamide chemical structure, C14H11ClIN3O2S, CAS 531546-39-1
2-(4-Chlorophenoxy)-N-[(5-iodopyridin-2-yl)carbamothioyl]acetamide
CAS 531546-39-1C14H11ClIN3O2S
2-(2-Chlorophenoxy)-N-[(5-iodopyridin-2-yl)carbamothioyl]acetamide chemical structure, C14H11ClIN3O2S, CAS 532421-56-0
2-(2-Chlorophenoxy)-N-[(5-iodopyridin-2-yl)carbamothioyl]acetamide
CAS 532421-56-0C14H11ClIN3O2S
2-(4-tert-Butylphenoxy)-N-[(5-chloropyridin-2-yl)carbamothioyl]acetamide chemical structure, C18H20ClN3O2S, CAS 425651-52-1
2-(4-tert-Butylphenoxy)-N-[(5-chloropyridin-2-yl)carbamothioyl]acetamide
CAS 425651-52-1C18H20ClN3O2S
2-(2-Bromo-4-methylphenoxy)-N-(pyridin-2-ylcarbamothioyl)acetamide chemical structure, C15H14BrN3O2S, CAS 642975-70-0
2-(2-Bromo-4-methylphenoxy)-N-(pyridin-2-ylcarbamothioyl)acetamide
CAS 642975-70-0C15H14BrN3O2S
2-(4-Methylphenoxy)-N-[(6-methylpyridin-2-yl)carbamothioyl]acetamide chemical structure, C16H17N3O2S, CAS 378765-40-3
2-(4-Methylphenoxy)-N-[(6-methylpyridin-2-yl)carbamothioyl]acetamide
CAS 378765-40-3C16H17N3O2S
N-[(5-Bromo-6-methylpyridin-2-yl)carbamothioyl]-2-(2-chlorophenoxy)acetamide chemical structure, C15H13BrClN3O2S, CAS 689750-83-2
N-[(5-Bromo-6-methylpyridin-2-yl)carbamothioyl]-2-(2-chlorophenoxy)acetamide
CAS 689750-83-2C15H13BrClN3O2S
N-(5-Iodo-6-methyl-2-pyridinyl)-N'-(phenoxyacetyl)thiourea chemical structure, C15H14IN3O2S, CAS 678983-96-5
N-(5-Iodo-6-methyl-2-pyridinyl)-N'-(phenoxyacetyl)thiourea
CAS 678983-96-5C15H14IN3O2S