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Murcko scaffold

N-(1,3-Thiazol-2-yl)pyridine-3-carboxamide scaffold

56 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
56
With full pages
21
Scaffold SMILES

O=C(Nc1nccs1)c1cccnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(1,3-Thiazol-2-yl)pyridine-3-carboxamide page
Murcko scaffold O=C(Nc1nccs1)c1cccnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 56 chemicals

RefChem:381639 chemical structure, C9H6N4O3S, CAS 64724-83-0
RefChem:381639
CAS 64724-83-0C9H6N4O3S
N-(1,3-Thiazol-2-yl)pyridine-3-carboxamide chemical structure, C9H7N3OS, CAS 14397-12-7
N-(1,3-Thiazol-2-yl)pyridine-3-carboxamide
CAS 14397-12-7C9H7N3OS
N-(4,5-Dimethyl-1,3-thiazol-2-yl)pyridine-3-carboxamide chemical structure, C11H11N3OS, CAS 300695-18-5
N-(4,5-Dimethyl-1,3-thiazol-2-yl)pyridine-3-carboxamide
CAS 300695-18-5C11H11N3OS
N-(4-Methyl-1,3-thiazol-2-yl)pyridine-3-carboxamide chemical structure, C10H9N3OS, CAS 5142-52-9
N-(4-Methyl-1,3-thiazol-2-yl)pyridine-3-carboxamide
CAS 5142-52-9C10H9N3OS
2-Chloro-N-(1,3-thiazol-2-yl)pyridine-3-carboxamide chemical structure, C9H6ClN3OS, CAS 85678-90-6
2-Chloro-N-(1,3-thiazol-2-yl)pyridine-3-carboxamide
CAS 85678-90-6C9H6ClN3OS
2-Chloro-N-(4-methyl-1,3-thiazol-2-yl)pyridine-3-carboxamide chemical structure, C10H8ClN3OS, CAS 85678-91-7
2-Chloro-N-(4-methyl-1,3-thiazol-2-yl)pyridine-3-carboxamide
CAS 85678-91-7C10H8ClN3OS
N-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-2-chloronicotinamide chemical structure, C12H10ClN3O2S, CAS 353769-09-2
N-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-2-chloronicotinamide
CAS 353769-09-2C12H10ClN3O2S
2-[(5-Bromo-pyridine-3-carbonyl)-amino]-4-methyl-thiazole-5-carboxylic acid ethyl ester chemical structure, C13H12BrN3O3S, CAS 6145-62-6
2-[(5-Bromo-pyridine-3-carbonyl)-amino]-4-methyl-thiazole-5-carboxylic acid ethyl ester
CAS 6145-62-6C13H12BrN3O3S
6-Chloro-N-(4-methyl-1,3-thiazol-2-yl)pyridine-3-carboxamide chemical structure, C10H8ClN3OS, CAS 764695-40-1
6-Chloro-N-(4-methyl-1,3-thiazol-2-yl)pyridine-3-carboxamide
CAS 764695-40-1C10H8ClN3OS
6-Chloro-N-(1,3-thiazol-2-yl)pyridine-3-carboxamide chemical structure, C9H6ClN3OS, CAS 761421-09-4
6-Chloro-N-(1,3-thiazol-2-yl)pyridine-3-carboxamide
CAS 761421-09-4C9H6ClN3OS
2-Ethoxy-N-(5-methyl-1,3-thiazol-2-yl)pyridine-3-carboxamide chemical structure, C12H13N3O2S, CAS 771512-62-0
2-Ethoxy-N-(5-methyl-1,3-thiazol-2-yl)pyridine-3-carboxamide
CAS 771512-62-0C12H13N3O2S
5-Bromo-N-(5-methyl-1,3-thiazol-2-yl)pyridine-3-carboxamide chemical structure, C10H8BrN3OS, CAS 785799-20-4
5-Bromo-N-(5-methyl-1,3-thiazol-2-yl)pyridine-3-carboxamide
CAS 785799-20-4C10H8BrN3OS
6-Chloro-N-(5-methyl-1,3-thiazol-2-yl)pyridine-3-carboxamide chemical structure, C10H8ClN3OS, CAS 784158-74-3
6-Chloro-N-(5-methyl-1,3-thiazol-2-yl)pyridine-3-carboxamide
CAS 784158-74-3C10H8ClN3OS
5-Bromo-N-(1,3-thiazol-2-yl)pyridine-3-carboxamide chemical structure, C9H6BrN3OS, CAS 448240-87-7
5-Bromo-N-(1,3-thiazol-2-yl)pyridine-3-carboxamide
CAS 448240-87-7C9H6BrN3OS
2-Methylsulfanyl-N-(5-methyl-1,3-thiazol-2-yl)pyridine-3-carboxamide chemical structure, C11H11N3OS2, CAS 752228-66-3
2-Methylsulfanyl-N-(5-methyl-1,3-thiazol-2-yl)pyridine-3-carboxamide
CAS 752228-66-3C11H11N3OS2
Ethyl 2-(6-chloropyridine-3-amido)-1,3-thiazole-4-carboxylate chemical structure, C12H10ClN3O3S, CAS 731816-90-3
Ethyl 2-(6-chloropyridine-3-amido)-1,3-thiazole-4-carboxylate
CAS 731816-90-3C12H10ClN3O3S
N-(4-tert-Butyl-1,3-thiazol-2-yl)-2-methylsulfanylpyridine-3-carboxamide chemical structure, C14H17N3OS2, CAS 794576-70-8
N-(4-tert-Butyl-1,3-thiazol-2-yl)-2-methylsulfanylpyridine-3-carboxamide
CAS 794576-70-8C14H17N3OS2
N-(4-tert-Butyl-1,3-thiazol-2-yl)-2-ethoxypyridine-3-carboxamide chemical structure, C15H19N3O2S, CAS 851453-24-2
N-(4-tert-Butyl-1,3-thiazol-2-yl)-2-ethoxypyridine-3-carboxamide
CAS 851453-24-2C15H19N3O2S
Ethyl 2-[2-(6-chloropyridine-3-amido)-1,3-thiazol-4-yl]acetate chemical structure, C13H12ClN3O3S, CAS 735305-55-2
Ethyl 2-[2-(6-chloropyridine-3-amido)-1,3-thiazol-4-yl]acetate
CAS 735305-55-2C13H12ClN3O3S
5-Bromo-N-(4-methyl-1,3-thiazol-2-yl)pyridine-3-carboxamide chemical structure, C10H8BrN3OS, CAS 796098-64-1
5-Bromo-N-(4-methyl-1,3-thiazol-2-yl)pyridine-3-carboxamide
CAS 796098-64-1C10H8BrN3OS
2-(Methylsulfanyl)-N-(1,3-thiazol-2-yl)pyridine-3-carboxamide chemical structure, C10H9N3OS2, CAS 801255-06-1
2-(Methylsulfanyl)-N-(1,3-thiazol-2-yl)pyridine-3-carboxamide
CAS 801255-06-1C10H9N3OS2
N-(4-tert-Butyl-1,3-thiazol-2-yl)-2-chloropyridine-3-carboxamide chemical structure, C13H14ClN3OS, CAS 444938-11-8
N-(4-tert-Butyl-1,3-thiazol-2-yl)-2-chloropyridine-3-carboxamide
CAS 444938-11-8C13H14ClN3OS
5,6-Dichloro-N-(5-methyl-1,3-thiazol-2-yl)pyridine-3-carboxamide chemical structure, C10H7Cl2N3OS, CAS 848056-77-9
5,6-Dichloro-N-(5-methyl-1,3-thiazol-2-yl)pyridine-3-carboxamide
CAS 848056-77-9C10H7Cl2N3OS
N-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-5,6-dichloropyridine-3-carboxamide chemical structure, C12H9Cl2N3O2S, CAS 848582-75-2
N-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-5,6-dichloropyridine-3-carboxamide
CAS 848582-75-2C12H9Cl2N3O2S