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Murcko scaffold

Ring system with 3 rings and 21 atoms

12 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
12
With full pages
4
Scaffold SMILES

O=C(Cc1ccccc1)N1CCNCC1CN1CCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1ccccc1)N1CCNCC1CN1CCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

4-((3,4-Dichlorophenyl)acetyl)-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylic acid methyl ester chemical structure, C19H25Cl2N3O3, CAS 126766-31-2
4-((3,4-Dichlorophenyl)acetyl)-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylic acid methyl ester
CAS 126766-31-2C19H25Cl2N3O3
GR 94839 chemical structure, C19H25Cl2N3O3, CAS 133407-20-2
GR 94839
CAS 133407-20-2C19H25Cl2N3O3
1-Piperazinecarboxylic acid, 4-(2-(3,4-dichlorophenyl)acetyl)-3-(1-pyrrolidinylmethyl)-, methyl ester, (2E)-2-butenedioate (1:1) chemical structure, C23H29Cl2N3O7, CAS 126766-32-3
1-Piperazinecarboxylic acid, 4-(2-(3,4-dichlorophenyl)acetyl)-3-(1-pyrrolidinylmethyl)-, methyl ester, (2E)-2-butenedioate (1:1)
CAS 126766-32-3C23H29Cl2N3O7
GR-103545 chemical structure, C19H25Cl2N3O3, CAS 126766-42-5
GR-103545
CAS 126766-42-5C19H25Cl2N3O3
(R)-Methyl 4-(2-(3,4-dichlorophenyl)acetyl)-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate fumarate chemical structure, C23H29Cl2N3O7, CAS 126766-43-6
(R)-Methyl 4-(2-(3,4-dichlorophenyl)acetyl)-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate fumarate
CAS 126766-43-6C23H29Cl2N3O7
2-(3,4-Dichlorophenyl)-1-[(2S)-2-(pyrrolidin-1-ylmethyl)piperazin-1-yl]ethanone chemical structure, C17H23Cl2N3O, CAS 260992-21-0
2-(3,4-Dichlorophenyl)-1-[(2S)-2-(pyrrolidin-1-ylmethyl)piperazin-1-yl]ethanone
CAS 260992-21-0C17H23Cl2N3O
1-(4-Acetyl-2-pyrrolidin-1-ylmethyl-piperazin-1-yl)-2-(3,4-dichloro-phenyl)-ethanone chemical structure, C19H25Cl2N3O2, CAS 126766-11-8
1-(4-Acetyl-2-pyrrolidin-1-ylmethyl-piperazin-1-yl)-2-(3,4-dichloro-phenyl)-ethanone
CAS 126766-11-8C19H25Cl2N3O2
1-{4-[2-(3,4-Dichloro-phenyl)-acetyl]-3-pyrrolidin-1-ylmethyl-piperazin-1-yl}-butan-1-one chemical structure, C21H29Cl2N3O2, CAS 149648-80-6
1-{4-[2-(3,4-Dichloro-phenyl)-acetyl]-3-pyrrolidin-1-ylmethyl-piperazin-1-yl}-butan-1-one
CAS 149648-80-6C21H29Cl2N3O2
(R)-Methyl 4-(2-(3,4-dichlorophenyl)acetyl)-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate chemical structure, C19H25Cl2N3O3, CAS 150133-20-3
(R)-Methyl 4-(2-(3,4-dichlorophenyl)acetyl)-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate
CAS 150133-20-3C19H25Cl2N3O3
1-[(3,4-Dichlorophenyl)acetyl]-2-(R)-[(1-pyrrolidinyl)methyl]piperazine chemical structure, C17H23Cl2N3O, CAS 126766-48-1
1-[(3,4-Dichlorophenyl)acetyl]-2-(R)-[(1-pyrrolidinyl)methyl]piperazine
CAS 126766-48-1C17H23Cl2N3O
1-Piperazinecarboxylic acid, 4-((3,4-dichlorophenyl)acetyl)-3-(1-pyrrolidinylmethyl)-, methyl-11c ester, (3R)- chemical structure, C19H25Cl2N3O3, CAS 460091-46-7
1-Piperazinecarboxylic acid, 4-((3,4-dichlorophenyl)acetyl)-3-(1-pyrrolidinylmethyl)-, methyl-11c ester, (3R)-
CAS 460091-46-7C19H25Cl2N3O3
Methyl (S)-4-(2-(3,4-dichlorophenyl)acetyl)-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate fumarate chemical structure, C23H29Cl2N3O7, CAS 150133-21-4
Methyl (S)-4-(2-(3,4-dichlorophenyl)acetyl)-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate fumarate
CAS 150133-21-4C23H29Cl2N3O7