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Murcko scaffold

Ring system with 3 rings and 23 atoms

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
7
With full pages
2
Scaffold SMILES

O=C(c1ccccc1NS(=O)(=O)c1ccccc1)N1CCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1NS(=O)(=O)c1ccccc1)N1CCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

4-Methoxy-3-methyl-N-[2-(pyrrolidine-1-carbonyl)phenyl]benzenesulfonamide chemical structure, C19H22N2O4S, CAS 643005-17-8
4-Methoxy-3-methyl-N-[2-(pyrrolidine-1-carbonyl)phenyl]benzenesulfonamide
CAS 643005-17-8C19H22N2O4S
N,4-dimethyl-N-[2-(pyrrolidine-1-carbonyl)phenyl]benzenesulfonamide chemical structure, C19H22N2O3S, CAS 642999-09-5
N,4-dimethyl-N-[2-(pyrrolidine-1-carbonyl)phenyl]benzenesulfonamide
CAS 642999-09-5C19H22N2O3S
4-Methoxy-N-[2-(pyrrolidine-1-carbonyl)phenyl]benzenesulfonamide chemical structure, C18H20N2O4S, CAS 444790-07-2
4-Methoxy-N-[2-(pyrrolidine-1-carbonyl)phenyl]benzenesulfonamide
CAS 444790-07-2C18H20N2O4S
2,3-Dichloro-4-methoxy-N-[2-(pyrrolidin-1-ylcarbonyl)phenyl]benzenesulfonamide chemical structure, C18H18Cl2N2O4S, CAS 641604-79-7
2,3-Dichloro-4-methoxy-N-[2-(pyrrolidin-1-ylcarbonyl)phenyl]benzenesulfonamide
CAS 641604-79-7C18H18Cl2N2O4S
4-Bromo-N-[2-(pyrrolidine-1-carbonyl)phenyl]benzenesulfonamide chemical structure, C17H17BrN2O3S, CAS 461648-56-6
4-Bromo-N-[2-(pyrrolidine-1-carbonyl)phenyl]benzenesulfonamide
CAS 461648-56-6C17H17BrN2O3S
3-Chloro-4-methoxy-N-[2-(pyrrolidine-1-carbonyl)phenyl]benzenesulfonamide chemical structure, C18H19ClN2O4S, CAS 838816-80-1
3-Chloro-4-methoxy-N-[2-(pyrrolidine-1-carbonyl)phenyl]benzenesulfonamide
CAS 838816-80-1C18H19ClN2O4S
3-Fluoro-4-methoxy-N-[2-(pyrrolidin-1-ylcarbonyl)phenyl]benzenesulfonamide chemical structure, C18H19FN2O4S, CAS 1125436-25-0
3-Fluoro-4-methoxy-N-[2-(pyrrolidin-1-ylcarbonyl)phenyl]benzenesulfonamide
CAS 1125436-25-0C18H19FN2O4S