Murcko scaffold
7-(Benzyloxy)-2,3-dihydrocyclopenta[c]chromen-4(1H)-one scaffold
51 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 22
- Chemicals
- 51
- With full pages
- 25
Scaffold SMILES
O=c1oc2cc(OCc3ccccc3)ccc2c2c1CCC2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 51 chemicals
![7-(Benzyloxy)-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C19H16O3, CAS 304675-00-1](/s/XQVDQBUDJDSCEP-UHFFFAOYSA-N.svg)
7-(Benzyloxy)-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 304675-00-1C19H16O3
![7-[(2-Fluorophenyl)methoxy]-2,3-dihydro-1H-cyclopenta[c]chromen-4-one chemical structure, C19H15FO3, CAS 302549-09-3](/s/IMLBTJVORFSRQQ-UHFFFAOYSA-N.svg)
7-[(2-Fluorophenyl)methoxy]-2,3-dihydro-1H-cyclopenta[c]chromen-4-one
CAS 302549-09-3C19H15FO3
![7-[(3-Chlorobenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C19H15ClO3, CAS 405908-35-2](/s/QZVYSMBDMUYEDU-UHFFFAOYSA-N.svg)
7-[(3-Chlorobenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 405908-35-2C19H15ClO3
![7-[(4-Fluorobenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C19H15FO3, CAS 303134-61-4](/s/JQRTYSCTPRCTEF-UHFFFAOYSA-N.svg)
7-[(4-Fluorobenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 303134-61-4C19H15FO3
![8-Chloro-7-[(4-fluorobenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C19H14ClFO3, CAS 303134-64-7](/s/MPXQPQYBCGGDSL-UHFFFAOYSA-N.svg)
8-Chloro-7-[(4-fluorobenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 303134-64-7C19H14ClFO3
![7-[(4-Chlorobenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C19H15ClO3, CAS 303134-70-5](/s/AZSFFSMOOOFXNL-UHFFFAOYSA-N.svg)
7-[(4-Chlorobenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 303134-70-5C19H15ClO3
![7-((4-Methoxybenzyl)oxy)-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C20H18O4, CAS 324055-70-1](/s/RABIQKHZRFLLCK-UHFFFAOYSA-N.svg)
7-((4-Methoxybenzyl)oxy)-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 324055-70-1C20H18O4
![7-[(2-Methoxybenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C20H18O4, CAS 374765-91-0](/s/CVQQOKYVXQYIJG-UHFFFAOYSA-N.svg)
7-[(2-Methoxybenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 374765-91-0C20H18O4
![7-[(3-Fluorobenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C19H15FO3, CAS 431924-82-2](/s/TZWVNKCROZUZAF-UHFFFAOYSA-N.svg)
7-[(3-Fluorobenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 431924-82-2C19H15FO3
![7-[(4-Methoxybenzyl)oxy]-6-methyl-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C21H20O4, CAS 374766-05-9](/s/ZEWOHZKPMUYUJB-UHFFFAOYSA-N.svg)
7-[(4-Methoxybenzyl)oxy]-6-methyl-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 374766-05-9C21H20O4
![7-(Benzyloxy)-8-propyl-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C22H22O3, CAS 374701-63-0](/s/XFMLSXGIXJZLCG-UHFFFAOYSA-N.svg)
7-(Benzyloxy)-8-propyl-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 374701-63-0C22H22O3
![7-[(4-Ethenylbenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C21H18O3, CAS 314743-63-0](/s/QCYXXDIOKGTXFB-UHFFFAOYSA-N.svg)
7-[(4-Ethenylbenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 314743-63-0C21H18O3
![8-Chloro-7-[(2-chlorobenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C19H14Cl2O3, CAS 301683-09-0](/s/KWWSMNOXDNSNKO-UHFFFAOYSA-N.svg)
8-Chloro-7-[(2-chlorobenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 301683-09-0C19H14Cl2O3
![8-Chloro-7-[(4-methoxybenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C20H17ClO4, CAS 374764-89-3](/s/WPQPNRRHYPPYKL-UHFFFAOYSA-N.svg)
8-Chloro-7-[(4-methoxybenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 374764-89-3C20H17ClO4
![7-[(2,6-Dichlorobenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C19H14Cl2O3, CAS 314743-61-8](/s/UFKPGDRJAZYWNR-UHFFFAOYSA-N.svg)
7-[(2,6-Dichlorobenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 314743-61-8C19H14Cl2O3
![Methyl 4-{[(4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl)oxy]methyl}benzoate chemical structure, C21H18O5, CAS 302549-10-6](/s/DJNFTCQTTKQPPR-UHFFFAOYSA-N.svg)
Methyl 4-{[(4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl)oxy]methyl}benzoate
CAS 302549-10-6C21H18O5
![7-[(3,4,5-Trimethoxybenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C22H22O6, CAS 376384-84-8](/s/DWGABPSTSRIORO-UHFFFAOYSA-N.svg)
7-[(3,4,5-Trimethoxybenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 376384-84-8C22H22O6
![6-Methyl-7-[(3,4,5-trimethoxybenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C23H24O6, CAS 376382-43-3](/s/DWMOBVXSQLBVDU-UHFFFAOYSA-N.svg)
6-Methyl-7-[(3,4,5-trimethoxybenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 376382-43-3C23H24O6
![8-Chloro-7-[(3,4,5-trimethoxybenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C22H21ClO6, CAS 376384-15-5](/s/OLMXZAPSAZRKGU-UHFFFAOYSA-N.svg)
8-Chloro-7-[(3,4,5-trimethoxybenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 376384-15-5C22H21ClO6
![8-Chloro-7-[(3-methoxyphenyl)methoxy]-2,3-dihydro-1H-cyclopenta[c]chromen-4-one chemical structure, C20H17ClO4, CAS 374921-16-1](/s/IPKLQUDMCHLXEX-UHFFFAOYSA-N.svg)
8-Chloro-7-[(3-methoxyphenyl)methoxy]-2,3-dihydro-1H-cyclopenta[c]chromen-4-one
CAS 374921-16-1C20H17ClO4
![8-Chloro-7-[(2-methoxyphenyl)methoxy]-2,3-dihydro-1H-cyclopenta[c]chromen-4-one chemical structure, C20H17ClO4, CAS 375357-29-2](/s/ZKSUKPBOYMTJKJ-UHFFFAOYSA-N.svg)
8-Chloro-7-[(2-methoxyphenyl)methoxy]-2,3-dihydro-1H-cyclopenta[c]chromen-4-one
CAS 375357-29-2C20H17ClO4
![Methyl 4-{[(8-hexyl-4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl)oxy]methyl}benzoate chemical structure, C27H30O5, CAS 302549-16-2](/s/WUCNZFRISIUFQT-UHFFFAOYSA-N.svg)
Methyl 4-{[(8-hexyl-4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl)oxy]methyl}benzoate
CAS 302549-16-2C27H30O5
![7-[(Pentafluorobenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C19H11F5O3, CAS 303134-58-9](/s/OMHCIHAZJOXWKB-UHFFFAOYSA-N.svg)
7-[(Pentafluorobenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 303134-58-9C19H11F5O3
![7-[(4-Chlorobenzyl)oxy]-8-hexyl-2,3-dihydrocyclopenta[c]chromen-4(1H)-one chemical structure, C25H27ClO3, CAS 332055-46-6](/s/GTHKUHBCSVOOPA-UHFFFAOYSA-N.svg)
7-[(4-Chlorobenzyl)oxy]-8-hexyl-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS 332055-46-6C25H27ClO3
- 7-[(4-Fluorobenzyl)oxy]-8-propyl-2,3-dihydrocyclopenta[c]chromen-4(1H)-one374698-94-9C22H21FO3
- 8-Hexyl-7-[(2-methoxybenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one374766-47-9C26H30O4
- 8-Hexyl-7-[(3-methoxybenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one374768-50-0C26H30O4
- 7-[(3-Methoxybenzyl)oxy]-6-methyl-2,3-dihydrocyclopenta[c]chromen-4(1H)-one374767-49-4C21H20O4
- 7-((3-Methoxybenzyl)oxy)-2,3-dihydrocyclopenta[c]chromen-4(1H)-one374765-29-4C20H18O4
- 8-Chloro-7-[(2,3,5,6-tetramethylbenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one380322-95-2C23H23ClO3
- 8-Chloro-7-[(4-chlorobenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one332055-43-3C19H14Cl2O3
- 7-[(2-Chloro-6-fluorobenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one314743-62-9C19H14ClFO3
- Methyl 4-{[(6-methyl-4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl)oxy]methyl}benzoate314743-81-2C22H20O5
- 7-[(2-Fluorophenyl)methoxy]-6-methyl-2,3-dihydro-1H-cyclopenta[c]chromen-4-one6137-83-3C20H17FO3
- 1 suppliers8-Chloro-7-[(4-methylphenyl)methoxy]-2,3-dihydro-1H-cyclopenta[c]chromen-4-one307549-17-3C20H17ClO3
- 7-[(2-Chloro-6-fluorobenzyl)oxy]-6-methyl-2,3-dihydrocyclopenta[c]chromen-4(1H)-one307549-08-2C20H16ClFO3
- 4-{[(6-Methyl-4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl)oxy]methyl}benzoic acid307549-10-6C21H18O5
- 1 suppliers7-(1-Phenylethoxy)-2,3-dihydrocyclopenta[c]chromen-4(1H)-one301227-33-8C20H18O3
- [(4-Oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl)oxy](phenyl)acetic acid405917-17-1C20H16O5
- Ethyl [(8-chloro-4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl)oxy](phenyl)acetate405917-12-6C22H19ClO5
- Ethyl [(6-methyl-4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl)oxy](phenyl)acetate405917-07-9C23H22O5
- Ethyl ((4-oxo-1,2,3,4-tetrahydrocyclopenta(C)chromen-7-yl)oxy)(phenyl)acetate405917-06-8C22H20O5
- [(6-Methyl-4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl)oxy](phenyl)acetic acid405917-18-2C21H18O5
- 7-[(2-Methoxybenzyl)oxy]-6-methyl-2,3-dihydrocyclopenta[c]chromen-4(1H)-one374768-65-7C21H20O4
- Methyl [(4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl)oxy](phenyl)acetate670243-18-2C21H18O5
- Methyl [(8-chloro-4-oxo-1,2,3,4-tetrahydrocyclopenta[c]chromen-7-yl)oxy](phenyl)acetate670243-36-4C21H17ClO5
- 8-Hexyl-7-(1-phenylethoxy)-2,3-dihydrocyclopenta[c]chromen-4(1H)-one374707-43-4C26H30O3
- 8-Hexyl-7-[(4-methoxybenzyl)oxy]-2,3-dihydrocyclopenta[c]chromen-4(1H)-one374767-07-4C26H30O4
Related scaffolds
Same ring framework with different atoms or bond orders
