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Murcko scaffold

1-Hydroxy-3-[(phenylsulfonyl)amino]thiolan-1-one scaffold

103 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 17
Chemicals: 103
With full pages: 20

Scaffold SMILES

O=S1(=O)CCC(NS(=O)(=O)c2ccccc2)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 1-Hydroxy-3-[(phenylsulfonyl)amino]thiolan-1-one page

Murcko scaffold O=S1(=O)CCC(NS(=O)(=O)c2ccccc2)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 103 chemicals

4-Chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)benzenesulfonamide chemical structure, C10H12ClNO4S2, CAS 307514-10-9

4-Chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)benzenesulfonamide

CAS 307514-10-9C₁₀H₁₂ClNO₄S₂

N-(1,1-Dioxidotetrahydrothiophen-3-yl)-4-fluorobenzenesulfonamide chemical structure, C10H12FNO4S2, CAS 380189-20-8

N-(1,1-Dioxidotetrahydrothiophen-3-yl)-4-fluorobenzenesulfonamide

CAS 380189-20-8C₁₀H₁₂FNO₄S₂

3-{Butyl[(4-methylphenyl)sulfonyl]amino}thiolane-1,1-dione chemical structure, C15H23NO4S2, CAS 499190-26-0

3-{Butyl[(4-methylphenyl)sulfonyl]amino}thiolane-1,1-dione

CAS 499190-26-0C₁₅H₂₃NO₄S₂

4-[(1,1-Dioxo-1lambda6-thiolan-3-yl)sulfamoyl]benzoic acid chemical structure, C11H13NO6S2, CAS 325850-98-4

4-[(1,1-Dioxo-1lambda6-thiolan-3-yl)sulfamoyl]benzoic acid

CAS 325850-98-4C₁₁H₁₃NO₆S₂

N-(1,1-Dioxidotetrahydrothiophen-3-yl)-4-methyl-3-nitrobenzenesulfonamide chemical structure, C11H14N2O6S2, CAS 324779-97-7

N-(1,1-Dioxidotetrahydrothiophen-3-yl)-4-methyl-3-nitrobenzenesulfonamide

CAS 324779-97-7C₁₁H₁₄N₂O₆S₂

3-{[(4-Fluorophenyl)sulfonyl]methylamino}thiolane-1,1-dione chemical structure, C11H14FNO4S2, CAS 380188-24-9

3-{[(4-Fluorophenyl)sulfonyl]methylamino}thiolane-1,1-dione

CAS 380188-24-9C₁₁H₁₄FNO₄S₂

4-Chloro-N-(3-methyl-1,1-dioxothiolan-3-yl)benzenesulfonamide chemical structure, C11H14ClNO4S2, CAS 443653-00-7

4-Chloro-N-(3-methyl-1,1-dioxothiolan-3-yl)benzenesulfonamide

CAS 443653-00-7C₁₁H₁₄ClNO₄S₂

3-[Butyl(phenylsulfonyl)amino]-1-hydroxythiolan-1-one chemical structure, C14H21NO4S2, CAS 507257-19-4

3-[Butyl(phenylsulfonyl)amino]-1-hydroxythiolan-1-one

CAS 507257-19-4C₁₄H₂₁NO₄S₂

1-Hydroxy-3-[(phenylsulfonyl)amino]thiolan-1-one chemical structure, C10H13NO4S2, CAS 327067-03-8

1-Hydroxy-3-[(phenylsulfonyl)amino]thiolan-1-one

CAS 327067-03-8C₁₀H₁₃NO₄S₂

3-{[(4-Nitrophenyl)sulfonyl]amino}thiolane-1,1-dione chemical structure, C10H12N2O6S2, CAS 328021-35-8

3-{[(4-Nitrophenyl)sulfonyl]amino}thiolane-1,1-dione

CAS 328021-35-8C₁₀H₁₂N₂O₆S₂

N-(4-{[(1,1-Dioxidotetrahydrothien-3-yl)amino]sulfonyl}phenyl)acetamide chemical structure, C12H16N2O5S2, CAS 446277-45-8

N-(4-{[(1,1-Dioxidotetrahydrothien-3-yl)amino]sulfonyl}phenyl)acetamide

CAS 446277-45-8C₁₂H₁₆N₂O₅S₂

N-[2-(4-{[(1,1-Dioxidotetrahydro-3-thienyl)(methyl)amino]sulfonyl}phenyl)ethyl]acetamide chemical structure, C15H22N2O5S2, CAS 698994-82-0

N-[2-(4-{[(1,1-Dioxidotetrahydro-3-thienyl)(methyl)amino]sulfonyl}phenyl)ethyl]acetamide

CAS 698994-82-0C₁₅H₂₂N₂O₅S₂

N-(1,1-Dioxidotetrahydrothiophen-3-yl)-3,4-dimethoxy-N-methylbenzenesulfonamide chemical structure, C13H19NO6S2, CAS 696628-75-8

N-(1,1-Dioxidotetrahydrothiophen-3-yl)-3,4-dimethoxy-N-methylbenzenesulfonamide

CAS 696628-75-8C₁₃H₁₉NO₆S₂

3-{Ethyl[(3-nitrophenyl)sulfonyl]amino}thiolane-1,1-dione chemical structure, C12H16N2O6S2, CAS 696625-88-4

3-{Ethyl[(3-nitrophenyl)sulfonyl]amino}thiolane-1,1-dione

CAS 696625-88-4C₁₂H₁₆N₂O₆S₂

N-Butyl-N-(1,1-dioxothiolan-3-yl)-4-fluorobenzenesulfonamide chemical structure, C14H20FNO4S2, CAS 833428-06-1

N-Butyl-N-(1,1-dioxothiolan-3-yl)-4-fluorobenzenesulfonamide

CAS 833428-06-1C₁₄H₂₀FNO₄S₂

N-(1,1-Dioxidotetrahydrothiophen-3-yl)-4-methoxybenzenesulfonamide chemical structure, C11H15NO5S2, CAS 300377-01-9

N-(1,1-Dioxidotetrahydrothiophen-3-yl)-4-methoxybenzenesulfonamide

CAS 300377-01-9C₁₁H₁₅NO₅S₂

N-(1,1-Dioxothiolan-3-yl)-N-methyl-4-nitrobenzenesulfonamide chemical structure, C11H14N2O6S2, CAS 380188-19-2

N-(1,1-Dioxothiolan-3-yl)-N-methyl-4-nitrobenzenesulfonamide

CAS 380188-19-2C₁₁H₁₄N₂O₆S₂

3-Methyl-3-[(phenylsulfonyl)amino]thiolane-1,1-dione chemical structure, C11H15NO4S2, CAS 443653-02-9

3-Methyl-3-[(phenylsulfonyl)amino]thiolane-1,1-dione

CAS 443653-02-9C₁₁H₁₅NO₄S₂

N-(1,1-Dioxo-1lambda6-thiolan-3-yl)-4-methoxy-N-methylbenzene-1-sulfonamide chemical structure, C12H17NO5S2, CAS 874652-00-3

N-(1,1-Dioxo-1lambda6-thiolan-3-yl)-4-methoxy-N-methylbenzene-1-sulfonamide

CAS 874652-00-3C₁₂H₁₇NO₅S₂

3-{Butyl[(4-chlorophenyl)sulfonyl]amino}thiolane-1,1-dione chemical structure, C14H20ClNO4S2, CAS 507257-14-9

3-{Butyl[(4-chlorophenyl)sulfonyl]amino}thiolane-1,1-dione

CAS 507257-14-9C₁₄H₂₀ClNO₄S₂

N-(1,1-Dioxothiolan-3-yl)-N-ethyl-4-fluorobenzenesulfonamide chemical structure, C12H16FNO4S2, CAS 850721-11-8

N-(1,1-Dioxothiolan-3-yl)-N-ethyl-4-fluorobenzenesulfonamide

CAS 850721-11-8C₁₂H₁₆FNO₄S₂

3-{[(4-Chlorophenyl)sulfonyl]methylamino}-1-hydroxythiolan-1-one chemical structure, C11H14ClNO4S2, CAS 443653-01-8

3-{[(4-Chlorophenyl)sulfonyl]methylamino}-1-hydroxythiolan-1-one

CAS 443653-01-8C₁₁H₁₄ClNO₄S₂

N-(1,1-Dioxidotetrahydrothiophen-3-yl)-4-methoxy-3-nitrobenzenesulfonamide chemical structure, C11H14N2O7S2, CAS 57249-74-8

N-(1,1-Dioxidotetrahydrothiophen-3-yl)-4-methoxy-3-nitrobenzenesulfonamide

CAS 57249-74-8C₁₁H₁₄N₂O₇S₂

3,4-Dichloro-N-(1,1-dioxo-1lambda6-thiolan-3-yl)-N-methylbenzene-1-sulfonamide chemical structure, C11H13Cl2NO4S2, CAS 852918-42-4

3,4-Dichloro-N-(1,1-dioxo-1lambda6-thiolan-3-yl)-N-methylbenzene-1-sulfonamide

CAS 852918-42-4C₁₁H₁₃Cl₂NO₄S₂