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Murcko scaffold

(Pyrazol-1-ylmethyl)pyridine scaffold

135 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
135
With full pages
4
Scaffold SMILES

c1ccc(Cn2cccn2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the (Pyrazol-1-ylmethyl)pyridine page
Murcko scaffold c1ccc(Cn2cccn2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 135 chemicals

1-(1-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}-1H-pyrazol-4-yl)-3-ethylurea chemical structure, C13H13ClF3N5O, CAS 2059513-69-6
1-(1-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}-1H-pyrazol-4-yl)-3-ethylurea
CAS 2059513-69-6C13H13ClF3N5O
N-(1-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}-1H-pyrazol-4-yl)propanamide chemical structure, C13H12ClF3N4O, CAS 2061178-07-0
N-(1-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}-1H-pyrazol-4-yl)propanamide
CAS 2061178-07-0C13H12ClF3N4O
N-(1-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}-1H-pyrazol-4-yl)-2,2,2-trifluoroacetamide chemical structure, C12H7ClF6N4O, CAS 2061269-63-2
N-(1-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}-1H-pyrazol-4-yl)-2,2,2-trifluoroacetamide
CAS 2061269-63-2C12H7ClF6N4O
N-(1-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]methyl}-1H-pyrazol-4-yl)-1-ethanesulfonamide chemical structure, C12H12ClF3N4O2S, CAS 2058815-02-2
N-(1-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]methyl}-1H-pyrazol-4-yl)-1-ethanesulfonamide
CAS 2058815-02-2C12H12ClF3N4O2S
N-(1-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]methyl}-1H-pyrazol-4-yl)(trifluoro)methanesulfonamide chemical structure, C11H7ClF6N4O2S, CAS 2061269-70-1
N-(1-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]methyl}-1H-pyrazol-4-yl)(trifluoro)methanesulfonamide
CAS 2061269-70-1C11H7ClF6N4O2S
1-[(3-Methylpyridin-2-yl)methyl]-1H-pyrazol-4-amine chemical structure, C10H12N4, CAS 1565443-29-9
1-[(3-Methylpyridin-2-yl)methyl]-1H-pyrazol-4-amine
CAS 1565443-29-9C10H12N4
3,5-Dimethyl-1-[(3-methyl-2-pyridinyl)methyl]-1H-pyrazol-4-amine chemical structure, C12H16N4, CAS 1567107-10-1
3,5-Dimethyl-1-[(3-methyl-2-pyridinyl)methyl]-1H-pyrazol-4-amine
CAS 1567107-10-1C12H16N4
4-Bromo-1-[(3-methylpyridin-2-yl)methyl]-1H-pyrazol-3-amine chemical structure, C10H11BrN4, CAS 1567098-29-6
4-Bromo-1-[(3-methylpyridin-2-yl)methyl]-1H-pyrazol-3-amine
CAS 1567098-29-6C10H11BrN4
4-Chloro-1-[(3-methylpyridin-2-yl)methyl]-1H-pyrazol-3-amine chemical structure, C10H11ClN4, CAS 1566690-30-9
4-Chloro-1-[(3-methylpyridin-2-yl)methyl]-1H-pyrazol-3-amine
CAS 1566690-30-9C10H11ClN4
4-Methyl-1-[(3-methylpyridin-2-yl)methyl]-1H-pyrazol-3-amine chemical structure, C11H14N4, CAS 1564913-46-7
4-Methyl-1-[(3-methylpyridin-2-yl)methyl]-1H-pyrazol-3-amine
CAS 1564913-46-7C11H14N4
2-[(3,5-Dimethyl-4-nitro-1H-pyrazol-1-yl)methyl]-3-methylPyridine chemical structure, C12H14N4O2, CAS 1799763-71-5
2-[(3,5-Dimethyl-4-nitro-1H-pyrazol-1-yl)methyl]-3-methylPyridine
CAS 1799763-71-5C12H14N4O2
2-((3,5-Dimethyl-4-nitro-1H-pyrazol-1-yl)methyl)nicotinonitrile chemical structure, C12H11N5O2, CAS 1799763-73-7
2-((3,5-Dimethyl-4-nitro-1H-pyrazol-1-yl)methyl)nicotinonitrile
CAS 1799763-73-7C12H11N5O2
6-[(3,5-Dimethyl-4-nitro-1H-pyrazol-1-yl)methyl]nicotinonitrile chemical structure, C12H11N5O2, CAS 1799763-95-3
6-[(3,5-Dimethyl-4-nitro-1H-pyrazol-1-yl)methyl]nicotinonitrile
CAS 1799763-95-3C12H11N5O2
6-[(4-Amino-3,5-dimethyl-1H-pyrazol-1-yl)methyl]nicotinonitrile chemical structure, C12H13N5, CAS 1799764-58-1
6-[(4-Amino-3,5-dimethyl-1H-pyrazol-1-yl)methyl]nicotinonitrile
CAS 1799764-58-1C12H13N5
3-Methyl-1-(pyridin-2-ylmethyl)-1H-pyrazol-4-amine chemical structure, C10H12N4, CAS 1393101-09-1
3-Methyl-1-(pyridin-2-ylmethyl)-1H-pyrazol-4-amine
CAS 1393101-09-1C10H12N4
5-Methyl-1-(pyridin-2-ylmethyl)-1H-pyrazol-4-amine chemical structure, C10H12N4, CAS 1393101-08-0
5-Methyl-1-(pyridin-2-ylmethyl)-1H-pyrazol-4-amine
CAS 1393101-08-0C10H12N4
3-Methyl-1-((6-methylpyridin-2-yl)methyl)-1H-pyrazol-4-amine chemical structure, C11H14N4, CAS 1393101-39-7
3-Methyl-1-((6-methylpyridin-2-yl)methyl)-1H-pyrazol-4-amine
CAS 1393101-39-7C11H14N4
5-Methyl-1-((6-methylpyridin-2-yl)methyl)-1H-pyrazol-4-amine chemical structure, C11H14N4, CAS 1393101-54-6
5-Methyl-1-((6-methylpyridin-2-yl)methyl)-1H-pyrazol-4-amine
CAS 1393101-54-6C11H14N4
6-[(3-Amino-1H-pyrazol-1-yl)methyl]-3-methyl-2-pyridinecarbonitrile chemical structure, C11H11N5, CAS 1838654-91-3
6-[(3-Amino-1H-pyrazol-1-yl)methyl]-3-methyl-2-pyridinecarbonitrile
CAS 1838654-91-3C11H11N5
6-[(3-Amino-1H-pyrazol-1-yl)methyl]-4-chloro-3-pyridinecarbonitrile chemical structure, C10H8ClN5, CAS 1838653-83-0
6-[(3-Amino-1H-pyrazol-1-yl)methyl]-4-chloro-3-pyridinecarbonitrile
CAS 1838653-83-0C10H8ClN5
1-((5-(Trifluoromethyl)pyridin-2-yl)methyl)-1H-pyrazol-3-amine chemical structure, C10H9F3N4, CAS 1838653-58-9
1-((5-(Trifluoromethyl)pyridin-2-yl)methyl)-1H-pyrazol-3-amine
CAS 1838653-58-9C10H9F3N4
3-Methyl-6-[(3-nitro-1H-pyrazol-1-yl)methyl]-2-pyridinecarbonitrile chemical structure, C11H9N5O2, CAS 1838654-90-2
3-Methyl-6-[(3-nitro-1H-pyrazol-1-yl)methyl]-2-pyridinecarbonitrile
CAS 1838654-90-2C11H9N5O2
6-[(3-Nitro-1H-pyrazol-1-yl)methyl]-3-pyridinecarbonitrile chemical structure, C10H7N5O2, CAS 1838653-23-8
6-[(3-Nitro-1H-pyrazol-1-yl)methyl]-3-pyridinecarbonitrile
CAS 1838653-23-8C10H7N5O2
6-[(3-Amino-1H-pyrazol-1-yl)methyl]-2-chloro-3-pyridinecarbonitrile chemical structure, C10H8ClN5, CAS 1838653-62-5
6-[(3-Amino-1H-pyrazol-1-yl)methyl]-2-chloro-3-pyridinecarbonitrile
CAS 1838653-62-5C10H8ClN5