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Murcko scaffold

Ring system with 2 rings and 8 atoms

76 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
8
Chemicals
76
With full pages
5
Scaffold SMILES

C1CC2OCOC2C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C1CC2OCOC2C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 76 chemicals

4,6-Dibromo-2,2-dimethyl-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]dioxole chemical structure, C8H12Br2O2, CAS 26048-12-4
4,6-Dibromo-2,2-dimethyl-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]dioxole
CAS 26048-12-4C8H12Br2O2
(3AS,4R,6S,6aR)-6-((tert-butoxycarbonyl)amino)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxole-4-carboxylic acid chemical structure, C14H23NO6
(3AS,4R,6S,6aR)-6-((tert-butoxycarbonyl)amino)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxole-4-carboxylic acid
C14H23NO6
2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol chemical structure, C10H19NO4, CAS 274693-55-9
2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol
CAS 274693-55-9C10H19NO4
(3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta(d)(1,3)dioxol-4-ol chemical structure, C8H15NO3, CAS 155899-66-4
(3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta(d)(1,3)dioxol-4-ol
CAS 155899-66-4C8H15NO3
[rel-(3aS,4S,6R,6aR)-4-(Hydroxymethyl)-2,2-dimethyl-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-6-yl]methanol chemical structure, C10H18O4, CAS 59210-93-4
[rel-(3aS,4S,6R,6aR)-4-(Hydroxymethyl)-2,2-dimethyl-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-6-yl]methanol
CAS 59210-93-4C10H18O4
(3aR,4S,6R,6aS)-6-Amino-N-ethyl-2,2-dimethyltetrahydro-2H,3aH-cyclopenta[d][1,3]dioxole-4-carboxamide chemical structure, C11H20N2O3, CAS 116856-50-9
(3aR,4S,6R,6aS)-6-Amino-N-ethyl-2,2-dimethyltetrahydro-2H,3aH-cyclopenta[d][1,3]dioxole-4-carboxamide
CAS 116856-50-9C11H20N2O3
[(3aR,4R,6R,6aS)-6-Amino-2,2-dimethyl-hexahydrocyclopenta[d][1,3]dioxol-4-yl]methanol chemical structure, C9H17NO3, CAS 132342-52-0
[(3aR,4R,6R,6aS)-6-Amino-2,2-dimethyl-hexahydrocyclopenta[d][1,3]dioxol-4-yl]methanol
CAS 132342-52-0C9H17NO3
(3AS,4S,6R,6aR)-6-ethenyl-2,2-dimethyl-hexahydrocyclopenta[d][1,3]dioxol-4-ol chemical structure, C10H16O3, CAS 698999-23-4
(3AS,4S,6R,6aR)-6-ethenyl-2,2-dimethyl-hexahydrocyclopenta[d][1,3]dioxol-4-ol
CAS 698999-23-4C10H16O3
tert-Butyl ((3AS,4R,6R,6AR)-6-(hydroxymethyl)-2,2-dimethyltetrahydro-3AH-cyclopenta[D][1,3]dioxol-4-yl)carbamate chemical structure, C14H25NO5, CAS 183505-22-8
tert-Butyl ((3AS,4R,6R,6AR)-6-(hydroxymethyl)-2,2-dimethyltetrahydro-3AH-cyclopenta[D][1,3]dioxol-4-yl)carbamate
CAS 183505-22-8C14H25NO5
(3aR,4S,6R,6aS)-2,2-Dimethyl-4-[(2-methylpropan-2-yl)oxycarbonylamino]-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]dioxole-6-carboxylate chemical structure, C14H22NO6-, CAS 220497-94-9
(3aR,4S,6R,6aS)-2,2-Dimethyl-4-[(2-methylpropan-2-yl)oxycarbonylamino]-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]dioxole-6-carboxylate
CAS 220497-94-9C14H22NO6-
(3aS,4R,6aR)-2,2-Dimethyl-hexahydrocyclopenta[d][1,3]dioxol-4-ol chemical structure, C8H14O3, CAS 62414-57-7
(3aS,4R,6aR)-2,2-Dimethyl-hexahydrocyclopenta[d][1,3]dioxol-4-ol
CAS 62414-57-7C8H14O3
[(3aR,6aS)-2,2-Dimethyl-hexahydrocyclopenta[d][1,3]dioxol-5-yl]methanol chemical structure, C9H16O3, CAS 1632382-02-5
[(3aR,6aS)-2,2-Dimethyl-hexahydrocyclopenta[d][1,3]dioxol-5-yl]methanol
CAS 1632382-02-5C9H16O3
(3aS,4R,6S,6aR)-6-Amino-2,2-dimethyl-hexahydrocyclopenta[d][1,3]dioxol-4-ol chemical structure, C8H15NO3, CAS 592533-90-9
(3aS,4R,6S,6aR)-6-Amino-2,2-dimethyl-hexahydrocyclopenta[d][1,3]dioxol-4-ol
CAS 592533-90-9C8H15NO3
6-Amino-2,2-dimethyltetrahydro-3AH-cyclopenta[D][1,3]dioxol-4-ol chemical structure, C8H15NO3, CAS 1446475-48-4
6-Amino-2,2-dimethyltetrahydro-3AH-cyclopenta[D][1,3]dioxol-4-ol
CAS 1446475-48-4C8H15NO3
tert-Butyl N-[(3aS,4R,6S,6aR)-6-hydroxy-2,2-dimethyl-hexahydrocyclopenta[d][1,3]dioxol-4-yl]carbamate chemical structure, C13H23NO5, CAS 324535-98-0
tert-Butyl N-[(3aS,4R,6S,6aR)-6-hydroxy-2,2-dimethyl-hexahydrocyclopenta[d][1,3]dioxol-4-yl]carbamate
CAS 324535-98-0C13H23NO5
(3aS,4R,6aR)-2,2-Dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-amine chemical structure, C8H15NO2, CAS 71728-52-4
(3aS,4R,6aR)-2,2-Dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-amine
CAS 71728-52-4C8H15NO2
rac-(3aR,5S,6aS)-2,2-dimethyl-hexahydrocyclopenta[d][1,3]dioxol-5-amine chemical structure, C8H15NO2, CAS 167298-48-8
rac-(3aR,5S,6aS)-2,2-dimethyl-hexahydrocyclopenta[d][1,3]dioxol-5-amine
CAS 167298-48-8C8H15NO2
(3aR,5S,6aS)-2,2-Dimethyl-hexahydrocyclopenta[d][1,3]dioxole-5-carboxylic acid chemical structure, C9H14O4, CAS 39798-13-5
(3aR,5S,6aS)-2,2-Dimethyl-hexahydrocyclopenta[d][1,3]dioxole-5-carboxylic acid
CAS 39798-13-5C9H14O4
rel-(3aR,4S,6aS)-Tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-amine chemical structure, C8H15NO2, CAS 167465-94-3
rel-(3aR,4S,6aS)-Tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-amine
CAS 167465-94-3C8H15NO2
2-[(6-Amino-2,2-dimethyl-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy]ethanol chemical structure, C10H19NO4, CAS 1785759-96-7
2-[(6-Amino-2,2-dimethyl-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy]ethanol
CAS 1785759-96-7C10H19NO4
2-(((3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol oxalate chemical structure, C12H21NO8, CAS 1215268-15-7
2-(((3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol oxalate
CAS 1215268-15-7C12H21NO8
(3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol hydrochloride chemical structure, C8H16ClNO3, CAS 220329-21-5
(3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol hydrochloride
CAS 220329-21-5C8H16ClNO3
(3aR,5r,6aS)-rel-2,2-Dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-5-ol chemical structure, C8H14O3, CAS 25494-07-9
(3aR,5r,6aS)-rel-2,2-Dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-5-ol
CAS 25494-07-9C8H14O3
Ticagrelor impurity 202 chemical structure, C10H17NO5, CAS 1402150-27-9
Ticagrelor impurity 202
CAS 1402150-27-9C10H17NO5