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Murcko scaffold

2,3-Dihydroquinazolin-4(1H)-one scaffold

42 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
42
With full pages
9
Scaffold SMILES

O=C1NCNc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,3-Dihydroquinazolin-4(1H)-one page
Murcko scaffold O=C1NCNc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 42 of 42 chemicals

Quinethazone chemical structure, C10H12ClN3O3S, CAS 73-49-4
Quinethazone
CAS 73-49-4C10H12ClN3O3S
4(1H)-Quinazolinone, 2,3-dihydro-7-chloro-1-(2-(dimethylamino)ethyl)-, hydrochloride chemical structure, C12H17Cl2N3O, CAS 73987-26-5
4(1H)-Quinazolinone, 2,3-dihydro-7-chloro-1-(2-(dimethylamino)ethyl)-, hydrochloride
CAS 73987-26-5C12H17Cl2N3O
4(1H)-Quinazolinone, 2,3-dihydro-1-(2-(dimethylamino)ethyl)-, hydrochloride chemical structure, C12H18ClN3O, CAS 73987-29-8
4(1H)-Quinazolinone, 2,3-dihydro-1-(2-(dimethylamino)ethyl)-, hydrochloride
CAS 73987-29-8C12H18ClN3O
4(1H)-Quinazolinone, 2,3-dihydro-7-chloro-1-(2-(dimethylamino)ethyl)-2-ethyl-, hydrochloride chemical structure, C14H21Cl2N3O, CAS 73987-25-4
4(1H)-Quinazolinone, 2,3-dihydro-7-chloro-1-(2-(dimethylamino)ethyl)-2-ethyl-, hydrochloride
CAS 73987-25-4C14H21Cl2N3O
Methyl 7-chloro-6-methoxy-2-(2-methoxy-2-oxoethyl)-4-oxo-1,2,3,4-tetrahydroquinazoline-2-carboxylate chemical structure, C14H15ClN2O6, CAS 34803-92-4
Methyl 7-chloro-6-methoxy-2-(2-methoxy-2-oxoethyl)-4-oxo-1,2,3,4-tetrahydroquinazoline-2-carboxylate
CAS 34803-92-4C14H15ClN2O6
2,2-Dimethyl-1,2,3-trihydroquinazolin-4-one chemical structure, C10H12N2O, CAS 77726-78-4
2,2-Dimethyl-1,2,3-trihydroquinazolin-4-one
CAS 77726-78-4C10H12N2O
2-Quinazolineacetic acid, 1,2,3,4-tetrahydro-2-(methoxycarbonyl)-4-oxo-, methyl ester chemical structure, C13H14N2O5, CAS 17244-35-8
2-Quinazolineacetic acid, 1,2,3,4-tetrahydro-2-(methoxycarbonyl)-4-oxo-, methyl ester
CAS 17244-35-8C13H14N2O5
3-Hydroxy-2,2-dimethyl-1,2,3,4-tetrahydroquinazolin-4-one chemical structure, C10H12N2O2, CAS 112484-56-7
3-Hydroxy-2,2-dimethyl-1,2,3,4-tetrahydroquinazolin-4-one
CAS 112484-56-7C10H12N2O2
3-(Isopropylideneamino)-2,2-dimethyl-2,3-dihydroquinazolin-4(1H)-one chemical structure, C13H17N3O, CAS 19558-22-6
3-(Isopropylideneamino)-2,2-dimethyl-2,3-dihydroquinazolin-4(1H)-one
CAS 19558-22-6C13H17N3O
Ethyl 4-oxo-2,2-bis(trifluoromethyl)-1H-quinazoline-3-carboxylate chemical structure, C13H10F6N2O3, CAS 170029-40-0
Ethyl 4-oxo-2,2-bis(trifluoromethyl)-1H-quinazoline-3-carboxylate
CAS 170029-40-0C13H10F6N2O3
2-(Chloromethyl)-2-methyl-1,2,3,4-tetrahydroquinazolin-4-one chemical structure, C10H11ClN2O, CAS 27545-02-4
2-(Chloromethyl)-2-methyl-1,2,3,4-tetrahydroquinazolin-4-one
CAS 27545-02-4C10H11ClN2O
2-Ethyl-2-methyl-1,3-dihydroquinazolin-4-one chemical structure, C11H14N2O, CAS 1012-59-5
2-Ethyl-2-methyl-1,3-dihydroquinazolin-4-one
CAS 1012-59-5C11H14N2O
2-(Dimethoxymethyl)-2-methyl-1,3-dihydroquinazolin-4-one chemical structure, C12H16N2O3, CAS 79974-01-9
2-(Dimethoxymethyl)-2-methyl-1,3-dihydroquinazolin-4-one
CAS 79974-01-9C12H16N2O3
2-Ethyl-2-methyl-3-[(1-methylpropylidene)amino]-2,3-dihydro-4(1H)-quinazolinone chemical structure, C15H21N3O, CAS 499119-71-0
2-Ethyl-2-methyl-3-[(1-methylpropylidene)amino]-2,3-dihydro-4(1H)-quinazolinone
CAS 499119-71-0C15H21N3O
2,2-Diethyl-2,3-dihydroquinazolin-4(1H)-one chemical structure, C12H16N2O, CAS 81038-76-8
2,2-Diethyl-2,3-dihydroquinazolin-4(1H)-one
CAS 81038-76-8C12H16N2O
2-Ethyl-4-oxo-1,2,3,4-tetrahydroquinazoline-2-carboxylic acid chemical structure, C11H12N2O3, CAS 129768-68-9
2-Ethyl-4-oxo-1,2,3,4-tetrahydroquinazoline-2-carboxylic acid
CAS 129768-68-9C11H12N2O3
2-Methyl-4-oxo-1,2,3,4-tetrahydroquinazoline-2-carboxylic acid chemical structure, C10H10N2O3, CAS 129768-69-0
2-Methyl-4-oxo-1,2,3,4-tetrahydroquinazoline-2-carboxylic acid
CAS 129768-69-0C10H10N2O3
2,3-Dihydro-2-methyl-4(1H)-quinazolinone chemical structure, C9H10N2O, CAS 54764-01-1
2,3-Dihydro-2-methyl-4(1H)-quinazolinone
CAS 54764-01-1C9H10N2O
2,3-Dihydroquinazolin-4(1H)-one chemical structure, C8H8N2O, CAS 5632-36-0
2,3-Dihydroquinazolin-4(1H)-one
CAS 5632-36-0C8H8N2O
3-Hydroxy-2,3-dihydro-1H-quinazolin-4-one chemical structure, C8H8N2O2, CAS 26032-24-6
3-Hydroxy-2,3-dihydro-1H-quinazolin-4-one
CAS 26032-24-6C8H8N2O2
3-Amino-2,3-dihydroquinazolin-4(1H)-one chemical structure, C8H9N3O, CAS 866473-19-0
3-Amino-2,3-dihydroquinazolin-4(1H)-one
CAS 866473-19-0C8H9N3O
2,3-Dihydro-2,2-bis(trifluoromethyl)-4(1H)-quinazolinone chemical structure, C10H6F6N2O, CAS 95274-65-0
2,3-Dihydro-2,2-bis(trifluoromethyl)-4(1H)-quinazolinone
CAS 95274-65-0C10H6F6N2O
3-Ethyl-2,2-dimethyl-2,3-dihydroquinazolin-4(1H)-one chemical structure, C12H16N2O, CAS 497057-57-5
3-Ethyl-2,2-dimethyl-2,3-dihydroquinazolin-4(1H)-one
CAS 497057-57-5C12H16N2O
2,2,5-Trimethyl-1,2,3,4-tetrahydroquinazolin-4-one chemical structure, C11H14N2O, CAS 1050885-58-9
2,2,5-Trimethyl-1,2,3,4-tetrahydroquinazolin-4-one
CAS 1050885-58-9C11H14N2O