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Murcko scaffold

3-Phenyl-1,4-diazaspiro[4.5]dec-3-en-2-one scaffold

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
7
With full pages
2
Scaffold SMILES

O=C1NC2(CCCCC2)N=C1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Phenyl-1,4-diazaspiro[4.5]dec-3-en-2-one page
Murcko scaffold O=C1NC2(CCCCC2)N=C1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

3-(4-Fluorophenyl)-1,4-diazaspiro[4.5]dec-3-en-2-one chemical structure, C14H15FN2O, CAS 899926-73-9
3-(4-Fluorophenyl)-1,4-diazaspiro[4.5]dec-3-en-2-one
CAS 899926-73-9C14H15FN2O
3-Phenyl-1,4-diazaspiro[4.5]dec-3-en-2-one chemical structure, C14H16N2O, CAS 93045-16-0
3-Phenyl-1,4-diazaspiro[4.5]dec-3-en-2-one
CAS 93045-16-0C14H16N2O
3-(4-Chlorophenyl)-1,4-diazaspiro[4.5]dec-3-en-2-one chemical structure, C14H15ClN2O, CAS 923975-81-9
3-(4-Chlorophenyl)-1,4-diazaspiro[4.5]dec-3-en-2-one
CAS 923975-81-9C14H15ClN2O
3-(4-Methylphenyl)-1,4-diazaspiro[4.5]dec-3-en-2-one chemical structure, C15H18N2O, CAS 899912-94-8
3-(4-Methylphenyl)-1,4-diazaspiro[4.5]dec-3-en-2-one
CAS 899912-94-8C15H18N2O
3-(4-Methoxyphenyl)-1,4-diazaspiro[4.5]dec-3-en-2-one chemical structure, C15H18N2O2, CAS 923975-89-7
3-(4-Methoxyphenyl)-1,4-diazaspiro[4.5]dec-3-en-2-one
CAS 923975-89-7C15H18N2O2
8-Methyl-3-phenyl-1,4-diazaspiro[4.5]dec-3-en-2-one chemical structure, C15H18N2O, CAS 1202247-39-9
8-Methyl-3-phenyl-1,4-diazaspiro[4.5]dec-3-en-2-one
CAS 1202247-39-9C15H18N2O
2-(2-Oxo-3-phenyl-1,4-diazaspiro[4.5]dec-3-en-1-yl)acetic acid chemical structure, C16H18N2O3, CAS 1234508-94-1
2-(2-Oxo-3-phenyl-1,4-diazaspiro[4.5]dec-3-en-1-yl)acetic acid
CAS 1234508-94-1C16H18N2O3