CompoundList
Sign in
Murcko scaffold

3-Phenyl-1-oxa-3,8-diazaspiro(4.5)decan-2-one scaffold

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
16
With full pages
8
Scaffold SMILES

O=C1OC2(CCNCC2)CN1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Phenyl-1-oxa-3,8-diazaspiro(4.5)decan-2-one page
Murcko scaffold O=C1OC2(CCNCC2)CN1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

3-Phenyl-1-oxa-3,8-diazaspiro(4.5)decan-2-one chemical structure, C13H16N2O2, CAS 77211-58-6
3-Phenyl-1-oxa-3,8-diazaspiro(4.5)decan-2-one
CAS 77211-58-6C13H16N2O2
3-(3-Methylphenyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one chemical structure, C14H18N2O2, CAS 1781518-25-9
3-(3-Methylphenyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
CAS 1781518-25-9C14H18N2O2
3-(3-Fluorophenyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one chemical structure, C13H15FN2O2, CAS 1047655-91-3
3-(3-Fluorophenyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
CAS 1047655-91-3C13H15FN2O2
3-Phenyl-1-oxa-3,8-diazaspiro(4.5)decan-2-one hydrochloride chemical structure, C13H17ClN2O2, CAS 320419-82-7
3-Phenyl-1-oxa-3,8-diazaspiro(4.5)decan-2-one hydrochloride
CAS 320419-82-7C13H17ClN2O2
3-(4-Chloro-2-fluorophenyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one chemical structure, C13H14ClFN2O2, CAS 1335220-63-7
3-(4-Chloro-2-fluorophenyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
CAS 1335220-63-7C13H14ClFN2O2
3-(4-Fluorophenyl)-1-oxa-3,8-diazaspiro(4.5)decan-2-one chemical structure, C13H15FN2O2, CAS 1047655-95-7
3-(4-Fluorophenyl)-1-oxa-3,8-diazaspiro(4.5)decan-2-one
CAS 1047655-95-7C13H15FN2O2
3-(3,4-Dimethylphenyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one chemical structure, C15H20N2O2, CAS 1353878-21-3
3-(3,4-Dimethylphenyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
CAS 1353878-21-3C15H20N2O2
3-(2,4-Dichlorophenyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one hydrochloride chemical structure, C13H15Cl3N2O2, CAS 1353878-16-6
3-(2,4-Dichlorophenyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one hydrochloride
CAS 1353878-16-6C13H15Cl3N2O2
3-(3,4-Dimethoxyphenyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one chemical structure, C15H20N2O4, CAS 1353878-11-1
3-(3,4-Dimethoxyphenyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
CAS 1353878-11-1C15H20N2O4
3-(4-Methylphenyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one chemical structure, C14H18N2O2, CAS 1360998-36-2
3-(4-Methylphenyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
CAS 1360998-36-2C14H18N2O2
4-{2-Oxo-1-oxa-3,8-diazaspiro[4.5]decan-3-ylbenzoic acid hydrochloride chemical structure, C14H17ClN2O4, CAS 1360914-54-0
4-{2-Oxo-1-oxa-3,8-diazaspiro[4.5]decan-3-ylbenzoic acid hydrochloride
CAS 1360914-54-0C14H17ClN2O4
4-(2-Oxo-1-oxa-3,8-diazaspiro[4.5]dec-3-yl)benzoic acid chemical structure, C14H16N2O4, CAS 1356386-23-6
4-(2-Oxo-1-oxa-3,8-diazaspiro[4.5]dec-3-yl)benzoic acid
CAS 1356386-23-6C14H16N2O4
3-(4-Methoxyphenyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one chemical structure, C14H18N2O3, CAS 1779849-44-3
3-(4-Methoxyphenyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
CAS 1779849-44-3C14H18N2O3
3-(4-(Methylsulfonyl)phenyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one chemical structure, C14H18N2O4S, CAS 1646637-63-9
3-(4-(Methylsulfonyl)phenyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
CAS 1646637-63-9C14H18N2O4S
3-(4-Aminophenyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one chemical structure, C13H17N3O2, CAS 1780733-86-9
3-(4-Aminophenyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
CAS 1780733-86-9C13H17N3O2
tert-Butyl 3-[4-(2-ethoxy-2-oxoethyl)phenyl]-2-oxo-1-oxa-3,8-diazaspiro[4.5]decane-8-carboxylate chemical structure, C22H30N2O6, CAS 1356386-13-4
tert-Butyl 3-[4-(2-ethoxy-2-oxoethyl)phenyl]-2-oxo-1-oxa-3,8-diazaspiro[4.5]decane-8-carboxylate
CAS 1356386-13-4C22H30N2O6