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Murcko scaffold

Ring system with 3 rings and 27 atoms

247 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
27
Chemicals
247
With full pages
4
Scaffold SMILES

O=C(CN(Cc1ccccc1)S(=O)(=O)c1ccccc1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CN(Cc1ccccc1)S(=O)(=O)c1ccccc1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 247 chemicals

2-{(2-Chlorobenzyl)[(4-methylphenyl)sulfonyl]amino}-N-(3-chloro-4-fluorophenyl)acetamide chemical structure, C22H19Cl2FN2O3S, CAS 593257-52-4
2-{(2-Chlorobenzyl)[(4-methylphenyl)sulfonyl]amino}-N-(3-chloro-4-fluorophenyl)acetamide
CAS 593257-52-4C22H19Cl2FN2O3S
2-[Benzyl-(4-bromophenyl)sulfonylamino]-N-(4-fluorophenyl)acetamide chemical structure, C21H18BrFN2O3S, CAS 428849-15-4
2-[Benzyl-(4-bromophenyl)sulfonylamino]-N-(4-fluorophenyl)acetamide
CAS 428849-15-4C21H18BrFN2O3S
2-[(4-Chlorophenyl)methyl-(4-methylphenyl)sulfonylamino]-N-(4-fluorophenyl)acetamide chemical structure, C22H20ClFN2O3S, CAS 496940-07-9
2-[(4-Chlorophenyl)methyl-(4-methylphenyl)sulfonylamino]-N-(4-fluorophenyl)acetamide
CAS 496940-07-9C22H20ClFN2O3S
2-[Benzyl-(4-fluorophenyl)sulfonylamino]-N-(4-propan-2-ylphenyl)acetamide chemical structure, C24H25FN2O3S, CAS 433252-38-1
2-[Benzyl-(4-fluorophenyl)sulfonylamino]-N-(4-propan-2-ylphenyl)acetamide
CAS 433252-38-1C24H25FN2O3S
2-[Benzenesulfonyl-[(4-bromophenyl)methyl]amino]-N-(2,6-dimethylphenyl)acetamide chemical structure, C23H23BrN2O3S, CAS 440098-22-6
2-[Benzenesulfonyl-[(4-bromophenyl)methyl]amino]-N-(2,6-dimethylphenyl)acetamide
CAS 440098-22-6C23H23BrN2O3S
2-[Benzenesulfonyl-[(4-bromophenyl)methyl]amino]-N-(2-fluorophenyl)acetamide chemical structure, C21H18BrFN2O3S, CAS 431979-70-3
2-[Benzenesulfonyl-[(4-bromophenyl)methyl]amino]-N-(2-fluorophenyl)acetamide
CAS 431979-70-3C21H18BrFN2O3S
N-(2,3-Dimethylphenyl)-2-[(2-fluorophenyl)methyl-(4-methylphenyl)sulfonylamino]acetamide chemical structure, C24H25FN2O3S, CAS 499112-71-9
N-(2,3-Dimethylphenyl)-2-[(2-fluorophenyl)methyl-(4-methylphenyl)sulfonylamino]acetamide
CAS 499112-71-9C24H25FN2O3S
N-(3,4-Dimethoxyphenyl)-2-[(2-fluorophenyl)methyl-(4-methylphenyl)sulfonylamino]acetamide chemical structure, C24H25FN2O5S, CAS 499112-72-0
N-(3,4-Dimethoxyphenyl)-2-[(2-fluorophenyl)methyl-(4-methylphenyl)sulfonylamino]acetamide
CAS 499112-72-0C24H25FN2O5S
N-(2,4-Dimethylphenyl)-2-{(4-fluorobenzyl)[(4-methylphenyl)sulfonyl]amino}acetamide chemical structure, C24H25FN2O3S, CAS 593257-04-6
N-(2,4-Dimethylphenyl)-2-{(4-fluorobenzyl)[(4-methylphenyl)sulfonyl]amino}acetamide
CAS 593257-04-6C24H25FN2O3S
2-[(4-Chlorophenyl)methyl-(4-chlorophenyl)sulfonylamino]-N-(3-methoxyphenyl)acetamide chemical structure, C22H20Cl2N2O4S, CAS 528563-39-5
2-[(4-Chlorophenyl)methyl-(4-chlorophenyl)sulfonylamino]-N-(3-methoxyphenyl)acetamide
CAS 528563-39-5C22H20Cl2N2O4S
N-(3-Acetylphenyl)-2-{(4-chlorobenzyl)[(4-chlorophenyl)sulfonyl]amino}acetamide chemical structure, C23H20Cl2N2O4S, CAS 593244-22-5
N-(3-Acetylphenyl)-2-{(4-chlorobenzyl)[(4-chlorophenyl)sulfonyl]amino}acetamide
CAS 593244-22-5C23H20Cl2N2O4S
N-(3-Acetylphenyl)-2-[[(4-chlorophenyl)sulfonyl](2,4-dichlorobenzyl)amino]acetamide chemical structure, C23H19Cl3N2O4S, CAS 499114-31-7
N-(3-Acetylphenyl)-2-[[(4-chlorophenyl)sulfonyl](2,4-dichlorobenzyl)amino]acetamide
CAS 499114-31-7C23H19Cl3N2O4S
N-(3-Bromophenyl)-2-[(4-methylphenyl)methyl-(4-methylphenyl)sulfonylamino]acetamide chemical structure, C23H23BrN2O3S, CAS 500133-48-2
N-(3-Bromophenyl)-2-[(4-methylphenyl)methyl-(4-methylphenyl)sulfonylamino]acetamide
CAS 500133-48-2C23H23BrN2O3S
Methyl 2-{[N-(4-chlorobenzyl)-N-(phenylsulfonyl)glycyl]amino}benzoate chemical structure, C23H21ClN2O5S, CAS 500133-73-3
Methyl 2-{[N-(4-chlorobenzyl)-N-(phenylsulfonyl)glycyl]amino}benzoate
CAS 500133-73-3C23H21ClN2O5S
N-(4-Ethoxyphenyl)-2-[(4-methylphenyl)methyl-(4-methylphenyl)sulfonylamino]acetamide chemical structure, C25H28N2O4S, CAS 500133-76-6
N-(4-Ethoxyphenyl)-2-[(4-methylphenyl)methyl-(4-methylphenyl)sulfonylamino]acetamide
CAS 500133-76-6C25H28N2O4S
N-(2-Methoxyphenyl)-2-[(4-methylphenyl)methyl-(4-methylphenyl)sulfonylamino]acetamide chemical structure, C24H26N2O4S, CAS 500133-90-4
N-(2-Methoxyphenyl)-2-[(4-methylphenyl)methyl-(4-methylphenyl)sulfonylamino]acetamide
CAS 500133-90-4C24H26N2O4S
N-(3-Acetylphenyl)-2-[(4-chlorophenyl)methyl-(4-methylphenyl)sulfonylamino]acetamide chemical structure, C24H23ClN2O4S, CAS 431054-93-2
N-(3-Acetylphenyl)-2-[(4-chlorophenyl)methyl-(4-methylphenyl)sulfonylamino]acetamide
CAS 431054-93-2C24H23ClN2O4S
Methyl 4-({N-(4-chlorobenzyl)-N-[(4-methylphenyl)sulfonyl]glycyl}amino)benzoate chemical structure, C24H23ClN2O5S, CAS 431983-70-9
Methyl 4-({N-(4-chlorobenzyl)-N-[(4-methylphenyl)sulfonyl]glycyl}amino)benzoate
CAS 431983-70-9C24H23ClN2O5S
2-[Benzenesulfonyl-[(3,4-dichlorophenyl)methyl]amino]-N-(2-ethoxyphenyl)acetamide chemical structure, C23H22Cl2N2O4S, CAS 500134-22-5
2-[Benzenesulfonyl-[(3,4-dichlorophenyl)methyl]amino]-N-(2-ethoxyphenyl)acetamide
CAS 500134-22-5C23H22Cl2N2O4S
2-(N-Benzyl-4-methylphenylsulfonamido)-N-(5-chloro-2-methoxyphenyl)acetamide chemical structure, C23H23ClN2O4S, CAS 332163-70-9
2-(N-Benzyl-4-methylphenylsulfonamido)-N-(5-chloro-2-methoxyphenyl)acetamide
CAS 332163-70-9C23H23ClN2O4S
2-[Benzenesulfonyl(benzyl)amino]-N-(2,4-dimethylphenyl)acetamide chemical structure, C23H24N2O3S, CAS 352562-63-1
2-[Benzenesulfonyl(benzyl)amino]-N-(2,4-dimethylphenyl)acetamide
CAS 352562-63-1C23H24N2O3S
2-[Benzyl-(2,5-dichlorophenyl)sulfonylamino]-N-(2-ethylphenyl)acetamide chemical structure, C23H22Cl2N2O3S, CAS 432021-15-3
2-[Benzyl-(2,5-dichlorophenyl)sulfonylamino]-N-(2-ethylphenyl)acetamide
CAS 432021-15-3C23H22Cl2N2O3S
2-[Benzyl-(2,5-dichlorophenyl)sulfonylamino]-N-(2-ethoxyphenyl)acetamide chemical structure, C23H22Cl2N2O4S, CAS 522662-04-0
2-[Benzyl-(2,5-dichlorophenyl)sulfonylamino]-N-(2-ethoxyphenyl)acetamide
CAS 522662-04-0C23H22Cl2N2O4S
2-[(3,4-Dichlorophenyl)methyl-(4-methylphenyl)sulfonylamino]-N-(3-fluorophenyl)acetamide chemical structure, C22H19Cl2FN2O3S, CAS 432517-12-9
2-[(3,4-Dichlorophenyl)methyl-(4-methylphenyl)sulfonylamino]-N-(3-fluorophenyl)acetamide
CAS 432517-12-9C22H19Cl2FN2O3S