Murcko scaffold
Ring system with 2 rings and 20 atoms
35 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 20
- Chemicals
- 35
- With full pages
- 4
Scaffold SMILES
O=S(=O)(NCCSCc1ccccc1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 35 of 35 chemicals
![3-Benzylsulfanyl-2-[(4-methylphenyl)sulfonylamino]propanoic acid chemical structure, C17H19NO4S2, CAS 4703-36-0](/s/MKQPPJXESXECOF-UHFFFAOYSA-N.svg)
3-Benzylsulfanyl-2-[(4-methylphenyl)sulfonylamino]propanoic acid
CAS 4703-36-0C17H19NO4S2
![Benzyl-N-[(4-methoxyphenyl)sulfonyl]cysteine chemical structure, C17H19NO5S2, CAS 52607-33-7](/s/HOJKNJQOJBDHFC-INIZCTEOSA-N.svg)
Benzyl-N-[(4-methoxyphenyl)sulfonyl]cysteine
CAS 52607-33-7C17H19NO5S2
![N-{2-[(4-Chlorobenzyl)sulfanyl]-2-methylpropyl}-4-methoxybenzenesulfonamide chemical structure, C18H22ClNO3S2, CAS 343372-99-6](/s/TWBMZECMVOFRGD-UHFFFAOYSA-N.svg)
N-{2-[(4-Chlorobenzyl)sulfanyl]-2-methylpropyl}-4-methoxybenzenesulfonamide
CAS 343372-99-6C18H22ClNO3S2
![N-{2-[(4-Chlorobenzyl)sulfanyl]-2-methylpropyl}-4-fluorobenzenesulfonamide chemical structure, C17H19ClFNO2S2, CAS 343373-00-2](/s/LMCZJKTYTRKZLL-UHFFFAOYSA-N.svg)
N-{2-[(4-Chlorobenzyl)sulfanyl]-2-methylpropyl}-4-fluorobenzenesulfonamide
CAS 343373-00-2C17H19ClFNO2S2
![N-{2-[(4-Fluorobenzyl)sulfanyl]-2-methylpropyl}-4-methoxybenzenesulfonamide chemical structure, C18H22FNO3S2, CAS 339104-23-3](/s/UNVKRHXUXICLQB-UHFFFAOYSA-N.svg)
N-{2-[(4-Fluorobenzyl)sulfanyl]-2-methylpropyl}-4-methoxybenzenesulfonamide
CAS 339104-23-3C18H22FNO3S2
![4-Bromo-N-{2-[(4-fluorobenzyl)sulfanyl]-2-methylpropyl}benzenesulfonamide chemical structure, C17H19BrFNO2S2, CAS 339104-26-6](/s/YGQUGMRFEYICGA-UHFFFAOYSA-N.svg)
4-Bromo-N-{2-[(4-fluorobenzyl)sulfanyl]-2-methylpropyl}benzenesulfonamide
CAS 339104-26-6C17H19BrFNO2S2
![2,5-Dichloro-N-{2-[(4-fluorobenzyl)sulfanyl]-2-methylpropyl}benzenesulfonamide chemical structure, C17H18Cl2FNO2S2, CAS 339104-38-0](/s/KHMVXDIFKBJOLX-UHFFFAOYSA-N.svg)
2,5-Dichloro-N-{2-[(4-fluorobenzyl)sulfanyl]-2-methylpropyl}benzenesulfonamide
CAS 339104-38-0C17H18Cl2FNO2S2
![4-Chloro-N-{2-[(4-fluorobenzyl)sulfanyl]-2-methylpropyl}benzenesulfonamide chemical structure, C17H19ClFNO2S2, CAS 339104-53-9](/s/XNTMSQDNNQLOID-UHFFFAOYSA-N.svg)
4-Chloro-N-{2-[(4-fluorobenzyl)sulfanyl]-2-methylpropyl}benzenesulfonamide
CAS 339104-53-9C17H19ClFNO2S2
![N-[2-[(4-Chlorophenyl)methylsulfanyl]ethyl]-4-methylbenzenesulfonamide chemical structure, C16H18ClNO2S2, CAS 335208-62-3](/s/AGPMIUSDQHKAPJ-UHFFFAOYSA-N.svg)
N-[2-[(4-Chlorophenyl)methylsulfanyl]ethyl]-4-methylbenzenesulfonamide
CAS 335208-62-3C16H18ClNO2S2
![N-{2-[(2,4-Dichlorobenzyl)sulfanyl]ethyl}-3,4-dimethoxybenzenesulfonamide chemical structure, C17H19Cl2NO4S2, CAS 432535-49-4](/s/NNJYVCPTAPTYJC-UHFFFAOYSA-N.svg)
N-{2-[(2,4-Dichlorobenzyl)sulfanyl]ethyl}-3,4-dimethoxybenzenesulfonamide
CAS 432535-49-4C17H19Cl2NO4S2
![N-{2-[(2,4-Dichlorobenzyl)sulfanyl]ethyl}-4-methoxybenzenesulfonamide chemical structure, C16H17Cl2NO3S2, CAS 432017-44-2](/s/HHYNBZCOKPSSSF-UHFFFAOYSA-N.svg)
N-{2-[(2,4-Dichlorobenzyl)sulfanyl]ethyl}-4-methoxybenzenesulfonamide
CAS 432017-44-2C16H17Cl2NO3S2
![N-{2-[(2,6-Dichlorobenzyl)sulfanyl]ethyl}-3,4-dimethoxybenzenesulfonamide chemical structure, C17H19Cl2NO4S2, CAS 462089-24-3](/s/QQWSUJCGJQPQEY-UHFFFAOYSA-N.svg)
N-{2-[(2,6-Dichlorobenzyl)sulfanyl]ethyl}-3,4-dimethoxybenzenesulfonamide
CAS 462089-24-3C17H19Cl2NO4S2
![N-{2-[(2-Methylbenzyl)sulfanyl]ethyl}benzenesulfonamide chemical structure, C16H19NO2S2, CAS 528533-56-4](/s/IRIGKCTVOHWLJQ-UHFFFAOYSA-N.svg)
N-{2-[(2-Methylbenzyl)sulfanyl]ethyl}benzenesulfonamide
CAS 528533-56-4C16H19NO2S2
![N-[4-[2-[(2,6-Dichlorophenyl)methylsulfanyl]ethylsulfamoyl]phenyl]acetamide chemical structure, C17H18Cl2N2O3S2, CAS 462089-95-8](/s/WSSZGAOWUUSADN-UHFFFAOYSA-N.svg)
N-[4-[2-[(2,6-Dichlorophenyl)methylsulfanyl]ethylsulfamoyl]phenyl]acetamide
CAS 462089-95-8C17H18Cl2N2O3S2
![4-Chloro-N-{2-[(2,6-dichlorobenzyl)sulfanyl]ethyl}benzenesulfonamide chemical structure, C15H14Cl3NO2S2, CAS 461646-59-3](/s/UIBGTFZSIVXWLR-UHFFFAOYSA-N.svg)
4-Chloro-N-{2-[(2,6-dichlorobenzyl)sulfanyl]ethyl}benzenesulfonamide
CAS 461646-59-3C15H14Cl3NO2S2
![3-Bromo-N-{2-[(2-chloro-6-fluorobenzyl)sulfanyl]ethyl}-4-methoxybenzenesulfonamide chemical structure, C16H16BrClFNO3S2, CAS 528863-06-1](/s/OSZRZOMYNWAFRQ-UHFFFAOYSA-N.svg)
3-Bromo-N-{2-[(2-chloro-6-fluorobenzyl)sulfanyl]ethyl}-4-methoxybenzenesulfonamide
CAS 528863-06-1C16H16BrClFNO3S2
![2,5-Dichloro-N-{2-[(2-chloro-6-fluorobenzyl)sulfanyl]ethyl}benzenesulfonamide chemical structure, C15H13Cl3FNO2S2, CAS 446261-79-6](/s/SMWASMFNWWNEDF-UHFFFAOYSA-N.svg)
2,5-Dichloro-N-{2-[(2-chloro-6-fluorobenzyl)sulfanyl]ethyl}benzenesulfonamide
CAS 446261-79-6C15H13Cl3FNO2S2
![4-Fluoro-N-{2-[(2-methylbenzyl)sulfanyl]ethyl}benzenesulfonamide chemical structure, C16H18FNO2S2, CAS 532950-13-3](/s/RRXWDWDHJBUFPF-UHFFFAOYSA-N.svg)
4-Fluoro-N-{2-[(2-methylbenzyl)sulfanyl]ethyl}benzenesulfonamide
CAS 532950-13-3C16H18FNO2S2
![3,4-Dimethoxy-N-{2-[(2-methylbenzyl)sulfanyl]ethyl}benzenesulfonamide chemical structure, C18H23NO4S2, CAS 461647-73-4](/s/VBOWMXJCLDZPJK-UHFFFAOYSA-N.svg)
3,4-Dimethoxy-N-{2-[(2-methylbenzyl)sulfanyl]ethyl}benzenesulfonamide
CAS 461647-73-4C18H23NO4S2
![N-{2-[(2,6-Dichlorobenzyl)sulfanyl]ethyl}-4-methoxybenzenesulfonamide chemical structure, C16H17Cl2NO3S2, CAS 535943-37-4](/s/DSMUXXPVIPLKHW-UHFFFAOYSA-N.svg)
N-{2-[(2,6-Dichlorobenzyl)sulfanyl]ethyl}-4-methoxybenzenesulfonamide
CAS 535943-37-4C16H17Cl2NO3S2
![2,3-Dichloro-N-{2-[(3-chlorobenzyl)sulfanyl]ethyl}-4-methoxybenzenesulfonamide chemical structure, C16H16Cl3NO3S2, CAS 640716-94-5](/s/SHXXFYPNHLQYGT-UHFFFAOYSA-N.svg)
2,3-Dichloro-N-{2-[(3-chlorobenzyl)sulfanyl]ethyl}-4-methoxybenzenesulfonamide
CAS 640716-94-5C16H16Cl3NO3S2
![2,4,6-Trimethyl-N-{2-[(2-methylbenzyl)sulfanyl]ethyl}benzenesulfonamide chemical structure, C19H25NO2S2, CAS 642995-72-0](/s/XMSQPPSNNYFBCV-UHFFFAOYSA-N.svg)
2,4,6-Trimethyl-N-{2-[(2-methylbenzyl)sulfanyl]ethyl}benzenesulfonamide
CAS 642995-72-0C19H25NO2S2
![N-{2-[(2-Chloro-6-fluorobenzyl)sulfanyl]ethyl}-4-methoxy-3-methylbenzenesulfonamide chemical structure, C17H19ClFNO3S2, CAS 641601-75-4](/s/DOPKYHRVDNEVLH-UHFFFAOYSA-N.svg)
N-{2-[(2-Chloro-6-fluorobenzyl)sulfanyl]ethyl}-4-methoxy-3-methylbenzenesulfonamide
CAS 641601-75-4C17H19ClFNO3S2
![2,5-Dichloro-N-{2-[(3-methylbenzyl)sulfanyl]ethyl}benzenesulfonamide chemical structure, C16H17Cl2NO2S2, CAS 641603-37-4](/s/RMSAJGYWHTZFJZ-UHFFFAOYSA-N.svg)
2,5-Dichloro-N-{2-[(3-methylbenzyl)sulfanyl]ethyl}benzenesulfonamide
CAS 641603-37-4C16H17Cl2NO2S2
- N-[2-[(4-Methylphenyl)methylsulfanyl]ethyl]-4-methylsulfanylbenzenesulfonamide831243-56-2C17H21NO2S3
- N-[2-[(3,4-Dichlorophenyl)methylsulfanyl]ethyl]-4-methylsulfanylbenzenesulfonamide832681-07-9C16H17Cl2NO2S3
- 4-Bromo-N-[2-[(4-chlorophenyl)methylsulfanyl]ethyl]benzenesulfonamide355414-63-0C15H15BrClNO2S2
- N-[2-(Benzylsulfanyl)ethyl]-4-chlorobenzenesulfonamide6247-92-3C15H16ClNO2S2
- 4-Fluoro-N-[2-[(4-methylphenyl)methylsulfanyl]ethyl]benzenesulfonamide425651-96-3C16H18FNO2S2
- N-{2-[(4-Chlorobenzyl)sulfanyl]ethyl}-4-methoxybenzenesulfonamide335212-15-2C16H18ClNO3S2
- N-[2-[(4-Chlorophenyl)methylsulfanyl]ethyl]benzenesulfonamide426217-67-6C15H16ClNO2S2
- N-[4-(2-Benzylsulfanylethylsulfamoyl)phenyl]acetamide28194-78-7C17H20N2O3S2
- N-(2-Benzylsulfanylethyl)-4-methylbenzenesulfonamide28194-69-6C16H19NO2S2
- N-{2-[(4-Methylbenzyl)sulfanyl]ethyl}benzenesulfonamide428481-01-0C16H19NO2S2
- 4-Butoxy-N-{2-[(4-fluorobenzyl)sulfanyl]-2-methylpropyl}benzenesulfonamide478245-95-3C21H28FNO3S2
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(COc1ccccc1)NN=Cc1ccccc1255 chemicals
O=C(NN=Cc1ccccc1)C(=O)Nc1ccccc1251 chemicals
O=C(NCNC(=S)Nc1ccccc1)c1ccccc179 chemicals
O=C(C=Cc1ccccc1)NCCc1ccccc145 chemicals
O=C(NCCc1ccccc1)OCc1ccccc142 chemicals
O=C(CCc1ccccc1)NCCc1ccccc138 chemicals
c1ccc(CCCNCCc2ccccc2)cc138 chemicals
O=C(CNc1ccccc1)NN=Cc1ccccc126 chemicals
O=S(=O)(NC=NCCc1ccccc1)c1ccccc126 chemicals
c1ccc(CCNCCOc2ccccc2)cc126 chemicals
O=C(CCCOc1ccccc1)Nc1ccccc121 chemicals
O=C(COc1ccccc1)NCCc1ccccc120 chemicals