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Murcko scaffold

Ring system with 2 rings and 18 atoms

9 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
18
Chemicals
9
With full pages
3
Scaffold SMILES

O=C1NCCN(C(=O)NCc2ccccc2)C1=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NCCN(C(=O)NCc2ccccc2)C1=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

(R)-(-)-alpha-(((4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl)amino)-4-hydroxybenzeneacetic acid chemical structure, C15H17N3O6, CAS 62893-24-7
(R)-(-)-alpha-(((4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl)amino)-4-hydroxybenzeneacetic acid
CAS 62893-24-7C15H17N3O6
(R)-2-(4-Ethyl-2,3-dioxopiperazine-1-carboxamido)-2-phenylacetic acid chemical structure, C15H17N3O5, CAS 63422-71-9
(R)-2-(4-Ethyl-2,3-dioxopiperazine-1-carboxamido)-2-phenylacetic acid
CAS 63422-71-9C15H17N3O5
(((4-Ethyl-2,3-dioxopiperazin-1-yl)carbonyl)amino)(4-hydroxyphenyl)acetic acid chemical structure, C15H17N3O6, CAS 79868-75-0
(((4-Ethyl-2,3-dioxopiperazin-1-yl)carbonyl)amino)(4-hydroxyphenyl)acetic acid
CAS 79868-75-0C15H17N3O6
(2S)-2-[(4-Ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetic acid chemical structure, C15H17N3O6, CAS 348088-68-6
(2S)-2-[(4-Ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetic acid
CAS 348088-68-6C15H17N3O6
(R)-2-(4-Ethyl-2,3-dioxopiperazine-1-carboxamido)-2-(4-hydroxyphenyl)acetyl chloride chemical structure, C15H16ClN3O5, CAS 74769-12-3
(R)-2-(4-Ethyl-2,3-dioxopiperazine-1-carboxamido)-2-(4-hydroxyphenyl)acetyl chloride
CAS 74769-12-3C15H16ClN3O5
(2S)-2-[(4-Ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-phenylacetic acid chemical structure, C15H17N3O5, CAS 122645-11-8
(2S)-2-[(4-Ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-phenylacetic acid
CAS 122645-11-8C15H17N3O5
Cefoperazone batsi chemical structure, C16H21BN4O7, CAS 1204325-21-2
Cefoperazone batsi
CAS 1204325-21-2C16H21BN4O7
Piperazinedione-carbonyl D-Phenylglycyl-glycine chemical structure, C17H20N4O6, CAS 2170771-47-6
Piperazinedione-carbonyl D-Phenylglycyl-glycine
CAS 2170771-47-6C17H20N4O6
Cefoperazone impurity N6 chemical structure, C15H16N3NaO6, CAS 82778-05-0
Cefoperazone impurity N6
CAS 82778-05-0C15H16N3NaO6