CompoundList
Sign in
Murcko scaffold

1-Phenyl-2-((4-phenyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)ethanone scaffold

24 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
24
With full pages
11
Scaffold SMILES

O=C(CSc1nnc(-c2cccnc2)n1-c1ccccc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Phenyl-2-((4-phenyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)ethanone page
Murcko scaffold O=C(CSc1nnc(-c2cccnc2)n1-c1ccccc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

1-(4-Fluorophenyl)-2-[(4-phenyl-5-pyridin-3-yl-4H-1,2,4-triazol-3-yl)thio]ethanone chemical structure, C21H15FN4OS, CAS 385374-08-3
1-(4-Fluorophenyl)-2-[(4-phenyl-5-pyridin-3-yl-4H-1,2,4-triazol-3-yl)thio]ethanone
CAS 385374-08-3C21H15FN4OS
1-(2,4-Dichlorophenyl)-2-[[4-(4-methoxyphenyl)-5-pyridin-3-yl-1,2,4-triazol-3-yl]sulfanyl]ethanone chemical structure, C22H16Cl2N4O2S, CAS 496776-07-9
1-(2,4-Dichlorophenyl)-2-[[4-(4-methoxyphenyl)-5-pyridin-3-yl-1,2,4-triazol-3-yl]sulfanyl]ethanone
CAS 496776-07-9C22H16Cl2N4O2S
1-(4-Methoxyphenyl)-2-[(4-phenyl-5-pyridin-3-yl-4H-1,2,4-triazol-3-yl)thio]ethanone chemical structure, C22H18N4O2S, CAS 433702-48-8
1-(4-Methoxyphenyl)-2-[(4-phenyl-5-pyridin-3-yl-4H-1,2,4-triazol-3-yl)thio]ethanone
CAS 433702-48-8C22H18N4O2S
2-((4-(4-BR-PH)-5-(3-Pyridinyl)-4H-1,2,4-triazol-3-yl)thio)-1-(4-F-PH)ethanone chemical structure, C21H14BrFN4OS, CAS 477330-58-8
2-((4-(4-BR-PH)-5-(3-Pyridinyl)-4H-1,2,4-triazol-3-yl)thio)-1-(4-F-PH)ethanone
CAS 477330-58-8C21H14BrFN4OS
1-(4-Chlorophenyl)-2-{[4-phenyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone chemical structure, C21H15ClN4OS, CAS 332909-85-0
1-(4-Chlorophenyl)-2-{[4-phenyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone
CAS 332909-85-0C21H15ClN4OS
1-(4-Bromophenyl)-2-{[4-(4-ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone chemical structure, C23H19BrN4O2S, CAS 587002-14-0
1-(4-Bromophenyl)-2-{[4-(4-ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone
CAS 587002-14-0C23H19BrN4O2S
2-((4-(4-Ethoxy-PH)5-(3-pyridinyl)4H-1,2,4-triazol-3-yl)thio)-1-(4-F-PH)ethanone chemical structure, C23H19FN4O2S, CAS 477331-51-4
2-((4-(4-Ethoxy-PH)5-(3-pyridinyl)4H-1,2,4-triazol-3-yl)thio)-1-(4-F-PH)ethanone
CAS 477331-51-4C23H19FN4O2S
1-(3-Nitrophenyl)-2-[(4-phenyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]ethanone chemical structure, C21H15N5O3S, CAS 433702-54-6
1-(3-Nitrophenyl)-2-[(4-phenyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]ethanone
CAS 433702-54-6C21H15N5O3S
1-(3,4-Dimethoxyphenyl)-2-{[4-(4-ethoxyphenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone chemical structure, C25H24N4O4S, CAS 477333-49-6
1-(3,4-Dimethoxyphenyl)-2-{[4-(4-ethoxyphenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone
CAS 477333-49-6C25H24N4O4S
2-((4-(4-Ethoxyphenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl)sulfanyl)-1-(4-methoxyphenyl)ethanone chemical structure, C24H22N4O3S, CAS 477329-43-4
2-((4-(4-Ethoxyphenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl)sulfanyl)-1-(4-methoxyphenyl)ethanone
CAS 477329-43-4C24H22N4O3S
2-((4-(4-BR-PH)-5-(3-Pyridinyl)-4H-1,2,4-triazol-3-yl)thio)-1-(4-meo-PH)ethanone chemical structure, C22H17BrN4O2S, CAS 477330-83-9
2-((4-(4-BR-PH)-5-(3-Pyridinyl)-4H-1,2,4-triazol-3-yl)thio)-1-(4-meo-PH)ethanone
CAS 477330-83-9C22H17BrN4O2S
1-(2,5-Dimethoxyphenyl)-2-{[4-(4-ethoxyphenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone chemical structure, C25H24N4O4S, CAS 477329-67-2
1-(2,5-Dimethoxyphenyl)-2-{[4-(4-ethoxyphenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone
CAS 477329-67-2C25H24N4O4S
1-Phenyl-2-((4-phenyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)ethanone chemical structure, C21H16N4OS, CAS 635701-33-6
1-Phenyl-2-((4-phenyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)ethanone
CAS 635701-33-6C21H16N4OS
2-{[4-(4-Ethoxyphenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-methylphenyl)ethanone chemical structure, C24H22N4O2S, CAS 613227-23-9
2-{[4-(4-Ethoxyphenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-methylphenyl)ethanone
CAS 613227-23-9C24H22N4O2S
2-{[4-(4-Bromophenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-methylphenyl)ethanone chemical structure, C22H17BrN4OS, CAS 679421-31-9
2-{[4-(4-Bromophenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-methylphenyl)ethanone
CAS 679421-31-9C22H17BrN4OS
2-((4-(4-BR-PH)-5-(3-Pyridinyl)-4H-1,2,4-triazol-3-yl)thio)-1-phenylethanone chemical structure, C21H15BrN4OS, CAS 738604-79-0
2-((4-(4-BR-PH)-5-(3-Pyridinyl)-4H-1,2,4-triazol-3-yl)thio)-1-phenylethanone
CAS 738604-79-0C21H15BrN4OS
2-{[4-(4-Bromophenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(3,4-dichlorophenyl)ethanone chemical structure, C21H13BrCl2N4OS, CAS 578000-53-0
2-{[4-(4-Bromophenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(3,4-dichlorophenyl)ethanone
CAS 578000-53-0C21H13BrCl2N4OS
1-(4-Bromophenyl)-2-{[4-phenyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethan-1-one chemical structure, C21H15BrN4OS, CAS 847471-94-7
1-(4-Bromophenyl)-2-{[4-phenyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethan-1-one
CAS 847471-94-7C21H15BrN4OS
2-({5-(6-Chloro-3-pyridyl)-4-[3-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-3-yl}thio)-1-phenylethan-1-one chemical structure, C22H14ClF3N4OS, CAS 680217-01-0
2-({5-(6-Chloro-3-pyridyl)-4-[3-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-3-yl}thio)-1-phenylethan-1-one
CAS 680217-01-0C22H14ClF3N4OS
1-(4-Chlorophenyl)-2-({5-(6-chloro-3-pyridyl)-4-[3-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-3-yl}thio)ethan-1-one chemical structure, C22H13Cl2F3N4OS, CAS 680217-02-1
1-(4-Chlorophenyl)-2-({5-(6-chloro-3-pyridyl)-4-[3-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-3-yl}thio)ethan-1-one
CAS 680217-02-1C22H13Cl2F3N4OS
2-[[5-(6-Chloropyridin-3-yl)-4-[3-(trifluoromethyl)phenyl]-1,2,4-triazol-3-yl]sulfanyl]-1-[3-(trifluoromethyl)phenyl]ethanone chemical structure, C23H13ClF6N4OS, CAS 680217-03-2
2-[[5-(6-Chloropyridin-3-yl)-4-[3-(trifluoromethyl)phenyl]-1,2,4-triazol-3-yl]sulfanyl]-1-[3-(trifluoromethyl)phenyl]ethanone
CAS 680217-03-2C23H13ClF6N4OS
2-((4-(4-BR-PH)-5-(3-Pyridinyl)-4H-1,2,4-triazol-3-yl)thio)-1-(2-CL-PH)ethanone chemical structure, C21H14BrClN4OS, CAS 577765-88-9
2-((4-(4-BR-PH)-5-(3-Pyridinyl)-4H-1,2,4-triazol-3-yl)thio)-1-(2-CL-PH)ethanone
CAS 577765-88-9C21H14BrClN4OS
1-(4-Ethylphenyl)-2-[[4-(2-methylphenyl)-5-pyridin-3-yl-1,2,4-triazol-3-yl]sulfanyl]propan-1-one chemical structure, C25H24N4OS, CAS 5650-82-8
1-(4-Ethylphenyl)-2-[[4-(2-methylphenyl)-5-pyridin-3-yl-1,2,4-triazol-3-yl]sulfanyl]propan-1-one
CAS 5650-82-8C25H24N4OS
1-(4-Methylphenyl)-2-{[4-phenyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethan-1-one chemical structure, C22H18N4OS, CAS 901109-22-6
1-(4-Methylphenyl)-2-{[4-phenyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethan-1-one
CAS 901109-22-6C22H18N4OS