CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 27 atoms

59 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
59
With full pages
20
Scaffold SMILES

O=C(CSc1nnc(-c2ccccc2)n1-c1ccccc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1nnc(-c2ccccc2)n1-c1ccccc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 59 chemicals

2-{[5-(4-Chlorophenyl)-4-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone chemical structure, C23H18ClN3O2S, CAS 681226-14-2
2-{[5-(4-Chlorophenyl)-4-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone
CAS 681226-14-2C23H18ClN3O2S
2-{[5-(2-Chlorophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone chemical structure, C22H16ClN3OS, CAS 397290-86-7
2-{[5-(2-Chlorophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone
CAS 397290-86-7C22H16ClN3OS
2-[[5-(3,4-Dimethoxyphenyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]-1-(4-methoxyphenyl)ethanone chemical structure, C25H23N3O4S, CAS 324052-32-6
2-[[5-(3,4-Dimethoxyphenyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]-1-(4-methoxyphenyl)ethanone
CAS 324052-32-6C25H23N3O4S
2-[(4,5-Diphenyl-1,2,4-triazol-3-yl)sulfanyl]-1-(4-methoxyphenyl)ethanone chemical structure, C23H19N3O2S, CAS 633322-30-2
2-[(4,5-Diphenyl-1,2,4-triazol-3-yl)sulfanyl]-1-(4-methoxyphenyl)ethanone
CAS 633322-30-2C23H19N3O2S
1-(4-Chlorophenyl)-2-{[5-(4-methoxyphenyl)-4-phenyl-4H-1,2,4-triazol-3-yl]thio}ethanone chemical structure, C23H18ClN3O2S, CAS 332906-28-2
1-(4-Chlorophenyl)-2-{[5-(4-methoxyphenyl)-4-phenyl-4H-1,2,4-triazol-3-yl]thio}ethanone
CAS 332906-28-2C23H18ClN3O2S
2-{[4-(4-Chlorophenyl)-5-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-methoxyphenyl)ethanone chemical structure, C24H20ClN3O3S, CAS 498547-07-2
2-{[4-(4-Chlorophenyl)-5-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(4-methoxyphenyl)ethanone
CAS 498547-07-2C24H20ClN3O3S
2-[[5-(3,4-Dimethoxyphenyl)-4-(4-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]-1-(3-nitrophenyl)ethanone chemical structure, C25H22N4O5S, CAS 412921-52-9
2-[[5-(3,4-Dimethoxyphenyl)-4-(4-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]-1-(3-nitrophenyl)ethanone
CAS 412921-52-9C25H22N4O5S
1-Phenyl-2-((4-phenyl-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)ethanone chemical structure, C25H23N3O4S, CAS 327094-29-1
1-Phenyl-2-((4-phenyl-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)ethanone
CAS 327094-29-1C25H23N3O4S
2-{[5-(4-Methylphenyl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone chemical structure, C23H19N3OS, CAS 332922-94-8
2-{[5-(4-Methylphenyl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone
CAS 332922-94-8C23H19N3OS
2-{[5-(4-Nitrophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone chemical structure, C22H16N4O3S, CAS 500210-83-3
2-{[5-(4-Nitrophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone
CAS 500210-83-3C22H16N4O3S
1-(4-Methoxyphenyl)-2-[[5-(3-methylphenyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]ethanone chemical structure, C24H21N3O2S, CAS 767326-61-4
1-(4-Methoxyphenyl)-2-[[5-(3-methylphenyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]ethanone
CAS 767326-61-4C24H21N3O2S
2-[(4,5-Diphenyl-1,2,4-triazol-3-yl)sulfanyl]-1-(4-fluorophenyl)ethanone chemical structure, C22H16FN3OS, CAS 482290-62-0
2-[(4,5-Diphenyl-1,2,4-triazol-3-yl)sulfanyl]-1-(4-fluorophenyl)ethanone
CAS 482290-62-0C22H16FN3OS
2-[[5-(3-Aminophenyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]-1-(4-fluorophenyl)ethanone chemical structure, C22H17FN4OS, CAS 701231-23-4
2-[[5-(3-Aminophenyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]-1-(4-fluorophenyl)ethanone
CAS 701231-23-4C22H17FN4OS
2-[(4,5-Diphenyl-1,2,4-triazol-3-yl)sulfanyl]-1-(3-nitrophenyl)ethanone chemical structure, C22H16N4O3S, CAS 381710-95-8
2-[(4,5-Diphenyl-1,2,4-triazol-3-yl)sulfanyl]-1-(3-nitrophenyl)ethanone
CAS 381710-95-8C22H16N4O3S
2-{[4-(4-Chlorophenyl)-5-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(2,5-dimethoxyphenyl)ethanone chemical structure, C25H22ClN3O4S, CAS 498547-09-4
2-{[4-(4-Chlorophenyl)-5-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(2,5-dimethoxyphenyl)ethanone
CAS 498547-09-4C25H22ClN3O4S
1-(4-Methoxyphenyl)-2-((5-(4-methoxyphenyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)ethanone chemical structure, C24H21N3O3S, CAS 326881-81-6
1-(4-Methoxyphenyl)-2-((5-(4-methoxyphenyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)ethanone
CAS 326881-81-6C24H21N3O3S
1-(4-Fluorophenyl)-2-((5-(4-methoxyphenyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)ethanone chemical structure, C23H18FN3O2S, CAS 326007-57-2
1-(4-Fluorophenyl)-2-((5-(4-methoxyphenyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)ethanone
CAS 326007-57-2C23H18FN3O2S
1-(3-Nitrophenyl)-2-[[4-phenyl-5-(3,4,5-trimethoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]ethanone chemical structure, C25H22N4O6S, CAS 327093-32-3
1-(3-Nitrophenyl)-2-[[4-phenyl-5-(3,4,5-trimethoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]ethanone
CAS 327093-32-3C25H22N4O6S
1-(4-Chlorophenyl)-2-{[4-phenyl-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone chemical structure, C25H22ClN3O4S, CAS 327094-35-9
1-(4-Chlorophenyl)-2-{[4-phenyl-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}ethanone
CAS 327094-35-9C25H22ClN3O4S
2-((5-(3-Chlorophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-1-(3-nitrophenyl)ethanone chemical structure, C22H15ClN4O3S, CAS 325694-42-6
2-((5-(3-Chlorophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-1-(3-nitrophenyl)ethanone
CAS 325694-42-6C22H15ClN4O3S
2-{[5-(3-Chlorophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone chemical structure, C22H16ClN3OS, CAS 324774-84-7
2-{[5-(3-Chlorophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenylethanone
CAS 324774-84-7C22H16ClN3OS
2-{[4-(4-Chlorophenyl)-5-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(3-methoxyphenyl)ethanone chemical structure, C24H20ClN3O3S, CAS 498547-10-7
2-{[4-(4-Chlorophenyl)-5-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(3-methoxyphenyl)ethanone
CAS 498547-10-7C24H20ClN3O3S
2-{[5-(4-Chlorophenyl)-4-(4-methylphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(3,4-dimethoxyphenyl)ethanone chemical structure, C25H22ClN3O3S, CAS 477332-89-1
2-{[5-(4-Chlorophenyl)-4-(4-methylphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(3,4-dimethoxyphenyl)ethanone
CAS 477332-89-1C25H22ClN3O3S
2-{[5-(4-Chlorophenyl)-4-(4-methylphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(2,5-dimethoxyphenyl)ethanone chemical structure, C25H22ClN3O3S, CAS 477331-66-1
2-{[5-(4-Chlorophenyl)-4-(4-methylphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(2,5-dimethoxyphenyl)ethanone
CAS 477331-66-1C25H22ClN3O3S