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Murcko scaffold

Ring system with 2 rings and 13 atoms

61 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
61
With full pages
4
Scaffold SMILES

C(=Cc1ncco1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(=Cc1ncco1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 61 chemicals

5-((3-Ethoxypropyl)amino)-2-(3,4,5-trimethoxystyryl)oxazole-4-carbonitrile chemical structure, C20H25N3O5, CAS 882246-17-5
5-((3-Ethoxypropyl)amino)-2-(3,4,5-trimethoxystyryl)oxazole-4-carbonitrile
CAS 882246-17-5C20H25N3O5
Ethyl 2-[(E)-2-phenylethenyl]-1,3-oxazole-4-carboxylate chemical structure, C14H13NO3, CAS 107367-69-1
Ethyl 2-[(E)-2-phenylethenyl]-1,3-oxazole-4-carboxylate
CAS 107367-69-1C14H13NO3
2-[(E)-2-Phenylethenyl]-5-(prop-2-enylamino)-1,3-oxazole-4-carbonitrile chemical structure, C15H13N3O, CAS 1164464-46-3
2-[(E)-2-Phenylethenyl]-5-(prop-2-enylamino)-1,3-oxazole-4-carbonitrile
CAS 1164464-46-3C15H13N3O
2-[(E)-2-(4-Ethoxyphenyl)ethenyl]-5-(ethylamino)-1,3-oxazole-4-carbonitrile chemical structure, C16H17N3O2, CAS 882246-29-9
2-[(E)-2-(4-Ethoxyphenyl)ethenyl]-5-(ethylamino)-1,3-oxazole-4-carbonitrile
CAS 882246-29-9C16H17N3O2
5-[3-(Dimethylamino)propylamino]-2-[(E)-2-(4-ethoxyphenyl)ethenyl]-1,3-oxazole-4-carbonitrile chemical structure, C19H24N4O2, CAS 882244-70-4
5-[3-(Dimethylamino)propylamino]-2-[(E)-2-(4-ethoxyphenyl)ethenyl]-1,3-oxazole-4-carbonitrile
CAS 882244-70-4C19H24N4O2
5-(3-Methoxypropylamino)-2-[(E)-2-phenylethenyl]-1,3-oxazole-4-carbonitrile chemical structure, C16H17N3O2, CAS 848917-13-5
5-(3-Methoxypropylamino)-2-[(E)-2-phenylethenyl]-1,3-oxazole-4-carbonitrile
CAS 848917-13-5C16H17N3O2
2-Styryloxazole-4-carbaldehyde chemical structure, C12H9NO2, CAS 259809-67-1
2-Styryloxazole-4-carbaldehyde
CAS 259809-67-1C12H9NO2
4-(Hydroxymethyl)-2-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1,3-oxazole chemical structure, C13H10F3NO2, CAS 832730-23-1
4-(Hydroxymethyl)-2-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1,3-oxazole
CAS 832730-23-1C13H10F3NO2
2-(2-Chlorostyryl)-5-methyloxazole-4-carboxylic acid chemical structure, C13H10ClNO3
2-(2-Chlorostyryl)-5-methyloxazole-4-carboxylic acid
C13H10ClNO3
2-(4-Chlorostyryl)-5-methyloxazole-4-carboxylic acid chemical structure, C13H10ClNO3
2-(4-Chlorostyryl)-5-methyloxazole-4-carboxylic acid
C13H10ClNO3
2-(3-Chlorostyryl)-5-methyloxazole-4-carboxylic acid chemical structure, C13H10ClNO3
2-(3-Chlorostyryl)-5-methyloxazole-4-carboxylic acid
C13H10ClNO3
5-Ethyl-2-styryloxazole-4-carboxylic acid chemical structure, C14H13NO3
5-Ethyl-2-styryloxazole-4-carboxylic acid
C14H13NO3
5-Isopropyl-2-styryloxazole-4-carboxylic acid chemical structure, C15H15NO3
5-Isopropyl-2-styryloxazole-4-carboxylic acid
C15H15NO3
5-Hexyl-2-styryloxazole-4-carboxylic acid chemical structure, C18H21NO3
5-Hexyl-2-styryloxazole-4-carboxylic acid
C18H21NO3
(5-Methyl-2-styryloxazol-4-yl)methanol chemical structure, C13H13NO2, CAS 89723-86-4
(5-Methyl-2-styryloxazol-4-yl)methanol
CAS 89723-86-4C13H13NO2
(2-(2-Chlorostyryl)-5-methyloxazol-4-yl)methanol chemical structure, C13H12ClNO2
(2-(2-Chlorostyryl)-5-methyloxazol-4-yl)methanol
C13H12ClNO2
(2-(3-Chlorostyryl)-5-methyloxazol-4-yl)methanol chemical structure, C13H12ClNO2, CAS 89724-05-0
(2-(3-Chlorostyryl)-5-methyloxazol-4-yl)methanol
CAS 89724-05-0C13H12ClNO2
(2-(4-Chlorostyryl)-5-methyloxazol-4-yl)methanol chemical structure, C13H12ClNO2
(2-(4-Chlorostyryl)-5-methyloxazol-4-yl)methanol
C13H12ClNO2
(5-Methyl-2-(3-(trifluoromethyl)styryl)oxazol-4-yl)methanol chemical structure, C14H12F3NO2
(5-Methyl-2-(3-(trifluoromethyl)styryl)oxazol-4-yl)methanol
C14H12F3NO2
(5-Ethyl-2-styryloxazol-4-yl)methanol chemical structure, C14H15NO2
(5-Ethyl-2-styryloxazol-4-yl)methanol
C14H15NO2
(5-Isopropyl-2-styryloxazol-4-yl)methanol chemical structure, C15H17NO2
(5-Isopropyl-2-styryloxazol-4-yl)methanol
C15H17NO2
(5-Hexyl-2-styryloxazol-4-yl)methanol chemical structure, C18H23NO2
(5-Hexyl-2-styryloxazol-4-yl)methanol
C18H23NO2
2-(5-Hexyl-2-styryloxazol-4-yl)acetic acid chemical structure, C19H23NO3
2-(5-Hexyl-2-styryloxazol-4-yl)acetic acid
C19H23NO3
2-(4-(Trifluoromethyl)styryl)oxazole-4-carboxylic acid chemical structure, C13H8F3NO3, CAS 832730-40-2
2-(4-(Trifluoromethyl)styryl)oxazole-4-carboxylic acid
CAS 832730-40-2C13H8F3NO3