CompoundList
Sign in
Murcko scaffold

1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((5-phenyl-1,3,4-oxadiazol-2-yl)thio)ethanone scaffold

18 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
18
With full pages
11
Scaffold SMILES

O=C(CSc1nnc(-c2ccccc2)o1)N1CCCc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((5-phenyl-1,3,4-oxadiazol-2-yl)thio)ethanone page
Murcko scaffold O=C(CSc1nnc(-c2ccccc2)o1)N1CCCc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

1-(3,4-Dihydro-2H-quinolin-1-yl)-2-[5-(3,5-dimethoxy-phenyl)-[1,3,4]oxadiazol-2-ylsulfanyl]-ethanone chemical structure, C21H21N3O4S, CAS 460732-67-6
1-(3,4-Dihydro-2H-quinolin-1-yl)-2-[5-(3,5-dimethoxy-phenyl)-[1,3,4]oxadiazol-2-ylsulfanyl]-ethanone
CAS 460732-67-6C21H21N3O4S
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((5-(3,4-dimethoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)ethanone chemical structure, C21H21N3O4S, CAS 486398-16-7
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((5-(3,4-dimethoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)ethanone
CAS 486398-16-7C21H21N3O4S
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)ethanone chemical structure, C20H19N3O3S, CAS 459845-49-9
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)ethanone
CAS 459845-49-9C20H19N3O3S
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl)thio)ethanone chemical structure, C19H16FN3O2S, CAS 459846-54-9
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl)thio)ethanone
CAS 459846-54-9C19H16FN3O2S
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((5-(o-tolyl)-1,3,4-oxadiazol-2-yl)thio)ethanone chemical structure, C20H19N3O2S, CAS 332357-73-0
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((5-(o-tolyl)-1,3,4-oxadiazol-2-yl)thio)ethanone
CAS 332357-73-0C20H19N3O2S
2-{[5-(4-Methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-1-(1,2,3,4-tetrahydroquinolin-1-yl)ethan-1-one chemical structure, C20H19N3O2S, CAS 557778-29-7
2-{[5-(4-Methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-1-(1,2,3,4-tetrahydroquinolin-1-yl)ethan-1-one
CAS 557778-29-7C20H19N3O2S
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((5-phenyl-1,3,4-oxadiazol-2-yl)thio)ethanone chemical structure, C19H17N3O2S, CAS 484694-56-6
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((5-phenyl-1,3,4-oxadiazol-2-yl)thio)ethanone
CAS 484694-56-6C19H17N3O2S
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((5-(m-tolyl)-1,3,4-oxadiazol-2-yl)thio)ethanone chemical structure, C20H19N3O2S, CAS 461001-15-0
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((5-(m-tolyl)-1,3,4-oxadiazol-2-yl)thio)ethanone
CAS 461001-15-0C20H19N3O2S
2-((5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-1-(3,4-dihydroquinolin-1(2H)-yl)ethanone chemical structure, C19H16ClN3O2S, CAS 537702-84-4
2-((5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-1-(3,4-dihydroquinolin-1(2H)-yl)ethanone
CAS 537702-84-4C19H16ClN3O2S
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((5-(2-methoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)ethanone chemical structure, C20H19N3O3S, CAS 850936-90-2
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((5-(2-methoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)ethanone
CAS 850936-90-2C20H19N3O3S
1-({[5-(3-Methoxyphenyl)-1,3,4-oxadiazol-2-yl]thio}acetyl)-1,2,3,4-tetrahydroquinoline chemical structure, C20H19N3O3S, CAS 484695-76-3
1-({[5-(3-Methoxyphenyl)-1,3,4-oxadiazol-2-yl]thio}acetyl)-1,2,3,4-tetrahydroquinoline
CAS 484695-76-3C20H19N3O3S
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((5-(4-fluorophenyl)-1,3,4-oxadiazol-2-yl)thio)ethanone chemical structure, C19H16FN3O2S, CAS 459861-19-9
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((5-(4-fluorophenyl)-1,3,4-oxadiazol-2-yl)thio)ethanone
CAS 459861-19-9C19H16FN3O2S
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((5-(4-ethoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)ethanone chemical structure, C21H21N3O3S, CAS 850937-20-1
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((5-(4-ethoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)ethanone
CAS 850937-20-1C21H21N3O3S
2-((5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-1-(3,4-dihydroquinolin-1(2H)-yl)ethanone chemical structure, C19H16ClN3O2S, CAS 332161-42-9
2-((5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-1-(3,4-dihydroquinolin-1(2H)-yl)ethanone
CAS 332161-42-9C19H16ClN3O2S
2-((5-(3-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-1-(3,4-dihydroquinolin-1(2H)-yl)ethanone chemical structure, C19H16ClN3O2S, CAS 850937-59-6
2-((5-(3-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-1-(3,4-dihydroquinolin-1(2H)-yl)ethanone
CAS 850937-59-6C19H16ClN3O2S
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((5-(3,4,5-trimethoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)ethanone chemical structure, C22H23N3O5S, CAS 851129-31-2
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((5-(3,4,5-trimethoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)ethanone
CAS 851129-31-2C22H23N3O5S
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((5-(3,4-dimethylphenyl)-1,3,4-oxadiazol-2-yl)thio)ethanone chemical structure, C21H21N3O2S, CAS 850379-56-5
1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((5-(3,4-dimethylphenyl)-1,3,4-oxadiazol-2-yl)thio)ethanone
CAS 850379-56-5C21H21N3O2S
1-({[5-(2,5-Dimethoxyphenyl)-1,3,4-oxadiazol-2-yl]thio}acetyl)-1,2,3,4-tetrahydroquinoline chemical structure, C21H21N3O4S, CAS 851129-69-6
1-({[5-(2,5-Dimethoxyphenyl)-1,3,4-oxadiazol-2-yl]thio}acetyl)-1,2,3,4-tetrahydroquinoline
CAS 851129-69-6C21H21N3O4S