CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 14 atoms

32 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
14
Chemicals
32
With full pages
8
Scaffold SMILES

c1ncc2ccc(C3CCCO3)n2n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ncc2ccc(C3CCCO3)n2n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 32 of 32 chemicals

Antiviral agent 17 chemical structure, C11H14N4O4, CAS 158227-81-7
Antiviral agent 17
CAS 158227-81-7C11H14N4O4
Gs-441524 chemical structure, C12H13N5O4, CAS 1191237-69-0
Gs-441524
CAS 1191237-69-0C12H13N5O4
(2R,3R,4R,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolane-2-carbonitrile chemical structure, C13H15N5O4, CAS 1191237-49-6
(2R,3R,4R,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolane-2-carbonitrile
CAS 1191237-49-6C13H15N5O4
GS-441524 triphosphate chemical structure, C12H16N5O13P3, CAS 1355149-45-9
GS-441524 triphosphate
CAS 1355149-45-9C12H16N5O13P3
(2S,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile chemical structure, C12H13N5O4, CAS 1355049-95-4
(2S,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile
CAS 1355049-95-4C12H13N5O4
L-Arabinononitrile, 5-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-4-deoxy-4-fluoro-2-C-(hydroxymethyl)-, (5S)- chemical structure, C12H12FN5O3, CAS 1770840-77-1
L-Arabinononitrile, 5-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-4-deoxy-4-fluoro-2-C-(hydroxymethyl)-, (5S)-
CAS 1770840-77-1C12H12FN5O3
(2R,3S,4R,5S)-5-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-2-(hydroxymethyl)oxolane-2-carbonitrile chemical structure, C12H13N5O4, CAS 1770840-57-7
(2R,3S,4R,5S)-5-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-2-(hydroxymethyl)oxolane-2-carbonitrile
CAS 1770840-57-7C12H13N5O4
GS-441524 monophosphate chemical structure, C12H14N5O7P, CAS 1911578-74-9
GS-441524 monophosphate
CAS 1911578-74-9C12H14N5O7P
((2R,3S,4R,5R)-5-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methyl trihydrogen diphosphate chemical structure, C12H15N5O10P2, CAS 1911578-77-2
((2R,3S,4R,5R)-5-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methyl trihydrogen diphosphate
CAS 1911578-77-2C12H15N5O10P2
Dephenoxy hydroxy remdesivir chemical structure, C15H19N6O8P, CAS 1911579-04-8
Dephenoxy hydroxy remdesivir
CAS 1911579-04-8C15H19N6O8P
GS-441524 sodium chemical structure, C12H12N5Na4O13P3, CAS 1355050-21-3
GS-441524 sodium
CAS 1355050-21-3C12H12N5Na4O13P3
7QK7Uhp3TK chemical structure, C12H14ClN5O4, CAS 2378280-82-9
7QK7Uhp3TK
CAS 2378280-82-9C12H14ClN5O4
GS-443902 (trisodium) chemical structure, C12H13N5Na3O13P3
GS-443902 (trisodium)
C12H13N5Na3O13P3
(2R)-5-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-4-fluoro-3-hydroxy-2-(hydroxymethyl)oxolane-2-carbonitrile chemical structure, C12H12FN5O3
(2R)-5-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-4-fluoro-3-hydroxy-2-(hydroxymethyl)oxolane-2-carbonitrile
C12H12FN5O3
(2R,3R,4R,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile chemical structure, C12H13N5O4, CAS 2324118-50-3
(2R,3R,4R,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile
CAS 2324118-50-3C12H13N5O4
GS-443902 trisodium chemical structure, C12H14N5Na3O13P3+
GS-443902 trisodium
C12H14N5Na3O13P3+
(2S,3R,4R,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile chemical structure, C12H13N5O4, CAS 2324118-49-0
(2S,3R,4R,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile
CAS 2324118-49-0C12H13N5O4
Obeldesivir chemical structure, C16H19N5O5, CAS 2647441-36-7
Obeldesivir
CAS 2647441-36-7C16H19N5O5
GS-621763 chemical structure, C24H31N5O7, CAS 2647442-13-3
GS-621763
CAS 2647442-13-3C24H31N5O7
Antiviral agent 18 chemical structure, C11H13ClN4O4, CAS 2170185-97-2
Antiviral agent 18
CAS 2170185-97-2C11H13ClN4O4
GS-441524 tris-isobutyryl ester chemical structure, C24H31N5O7, CAS 2563617-99-0
GS-441524 tris-isobutyryl ester
CAS 2563617-99-0C24H31N5O7
RefChem:934152 chemical structure, C24H31N5O7, CAS 2647442-33-7
RefChem:934152
CAS 2647442-33-7C24H31N5O7
Deuremidevir hydrobromide chemical structure, C24H32BrN5O7, CAS 2779498-79-0
Deuremidevir hydrobromide
CAS 2779498-79-0C24H32BrN5O7
Des-phenyl-remdesivir chemical structure, C21H31N6O8P, CAS 2768006-90-0
Des-phenyl-remdesivir
CAS 2768006-90-0C21H31N6O8P