Murcko scaffold
N-Thiophen-3-ylbenzenesulfonamide scaffold
68 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 15
- Chemicals
- 68
- With full pages
- 4
Scaffold SMILES
O=S(=O)(Nc1ccsc1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 68 chemicals
![Methyl 3-{[(4-chlorophenyl)sulfonyl]amino}thiophene-2-carboxylate chemical structure, C12H10ClNO4S2, CAS 438613-88-8](/s/KJVFBQUJFMDZCF-UHFFFAOYSA-N.svg)
Methyl 3-{[(4-chlorophenyl)sulfonyl]amino}thiophene-2-carboxylate
CAS 438613-88-8C12H10ClNO4S2
Methyl 3-(4-methoxybenzenesulfonamido)thiophene-2-carboxylate
CAS 206192-42-9C13H13NO5S2
![Methyl 3-[(2,5-dichlorophenyl)sulfonylamino]thiophene-2-carboxylate chemical structure, C12H9Cl2NO4S2, CAS 5693-34-5](/s/XEYNCYLUBROHMJ-UHFFFAOYSA-N.svg)
Methyl 3-[(2,5-dichlorophenyl)sulfonylamino]thiophene-2-carboxylate
CAS 5693-34-5C12H9Cl2NO4S2
N-(2-Acetyl-3-thienyl)-4-chlorobenzenesulfonamide
CAS 676120-27-7C12H10ClNO3S2
![Methyl 3-{[(4-methylphenyl)sulfonyl]amino}-2-thiophenecarboxylate chemical structure, C13H13NO4S2, CAS 79128-72-6](/s/JTRQMORGBIFWFY-UHFFFAOYSA-N.svg)
Methyl 3-{[(4-methylphenyl)sulfonyl]amino}-2-thiophenecarboxylate
CAS 79128-72-6C13H13NO4S2
![Methyl 3-[[[4-(acetylamino)phenyl]sulfonyl]amino]-2-thiophenecarboxylate chemical structure, C14H14N2O5S2, CAS 544462-64-8](/s/LPSONDAXRDNWQR-UHFFFAOYSA-N.svg)
Methyl 3-[[[4-(acetylamino)phenyl]sulfonyl]amino]-2-thiophenecarboxylate
CAS 544462-64-8C14H14N2O5S2
![Methyl 3-[[(3,5-dichlorophenyl)sulfonyl]amino]-2-thiophenecarboxylate chemical structure, C12H9Cl2NO4S2, CAS 682741-23-7](/s/KRHGLEYNYMDZLW-UHFFFAOYSA-N.svg)
Methyl 3-[[(3,5-dichlorophenyl)sulfonyl]amino]-2-thiophenecarboxylate
CAS 682741-23-7C12H9Cl2NO4S2
N-(2-Cyano-3-thienyl)-4-methylbenzenesulfonamide
CAS 866009-12-3C12H10N2O2S2
![Methyl 3-{[(3-chlorophenyl)sulfonyl]amino}-4-methyl-2-thiophenecarboxylate chemical structure, C13H12ClNO4S2, CAS 866150-21-2](/s/SXZSSKSAJOEBQK-UHFFFAOYSA-N.svg)
Methyl 3-{[(3-chlorophenyl)sulfonyl]amino}-4-methyl-2-thiophenecarboxylate
CAS 866150-21-2C13H12ClNO4S2
Methyl 3-(((2,4-dichlorophenyl)sulfonyl)amino)thiophene-2-carboxylate
CAS 1023511-50-3C12H9Cl2NO4S2
![Methyl 3-[(phenylsulfonyl)amino]thiophene-2-carboxylate chemical structure, C12H11NO4S2, CAS 409364-77-8](/s/DOSQXDPMQNFOHS-UHFFFAOYSA-N.svg)
Methyl 3-[(phenylsulfonyl)amino]thiophene-2-carboxylate
CAS 409364-77-8C12H11NO4S2
![Methyl 3-{[(4-ethoxyphenyl)sulfonyl]amino}thiophene-2-carboxylate chemical structure, C14H15NO5S2, CAS 898088-43-2](/s/KNRIOEYBYPDUCA-UHFFFAOYSA-N.svg)
Methyl 3-{[(4-ethoxyphenyl)sulfonyl]amino}thiophene-2-carboxylate
CAS 898088-43-2C14H15NO5S2
![Methyl 3-{[(2,5-difluorophenyl)sulfonyl]amino}thiophene-2-carboxylate chemical structure, C12H9F2NO4S2, CAS 898088-55-6](/s/WDJSGSDPRUMTDJ-UHFFFAOYSA-N.svg)
Methyl 3-{[(2,5-difluorophenyl)sulfonyl]amino}thiophene-2-carboxylate
CAS 898088-55-6C12H9F2NO4S2
![Methyl 3-{[(3,4-dimethylphenyl)sulfonyl]amino}thiophene-2-carboxylate chemical structure, C14H15NO4S2, CAS 879844-17-4](/s/GWNPQVUBVIIIGX-UHFFFAOYSA-N.svg)
Methyl 3-{[(3,4-dimethylphenyl)sulfonyl]amino}thiophene-2-carboxylate
CAS 879844-17-4C14H15NO4S2
![3-{[(4-Chlorophenyl)sulfonyl]amino}thiophene-2-carboxylic acid chemical structure, C11H8ClNO4S2, CAS 254878-28-9](/s/KFSMKLIYYYGIKW-UHFFFAOYSA-N.svg)
3-{[(4-Chlorophenyl)sulfonyl]amino}thiophene-2-carboxylic acid
CAS 254878-28-9C11H8ClNO4S2
![3-{[(4-Bromophenyl)sulfonyl]amino}thiophene-2-carboxylic acid chemical structure, C11H8BrNO4S2, CAS 959352-55-7](/s/WTKNIIJLHKRYGT-UHFFFAOYSA-N.svg)
3-{[(4-Bromophenyl)sulfonyl]amino}thiophene-2-carboxylic acid
CAS 959352-55-7C11H8BrNO4S2
![3-{[(4-Methylphenyl)sulfonyl]amino}thiophene-2-carboxylic acid chemical structure, C12H11NO4S2, CAS 926213-55-0](/s/QMGTZNNYUCJDJV-UHFFFAOYSA-N.svg)
3-{[(4-Methylphenyl)sulfonyl]amino}thiophene-2-carboxylic acid
CAS 926213-55-0C12H11NO4S2
![3-{[(4-Fluorophenyl)sulfonyl]amino}thiophene-2-carboxylic acid chemical structure, C11H8FNO4S2, CAS 926227-92-1](/s/CASGSTUQAISKTI-UHFFFAOYSA-N.svg)
3-{[(4-Fluorophenyl)sulfonyl]amino}thiophene-2-carboxylic acid
CAS 926227-92-1C11H8FNO4S2
![3-[(Phenylsulfonyl)amino]thiophene-2-carboxylic acid chemical structure, C11H9NO4S2, CAS 409364-78-9](/s/BFPYDKRUFUMDTD-UHFFFAOYSA-N.svg)
3-[(Phenylsulfonyl)amino]thiophene-2-carboxylic acid
CAS 409364-78-9C11H9NO4S2
3-(4-Methoxybenzenesulfonamido)thiophene-2-carboxylic acid
CAS 1153392-91-6C12H11NO5S2
amino]thiophene-2-carboxylic acid chemical structure, C16H19NO4S2, CAS 1111300-43-6](/s/NSBXTNQCAWMEFB-UHFFFAOYSA-N.svg)
3-[[(4-tert-Butylphenyl)sulfonyl](methyl)amino]thiophene-2-carboxylic acid
CAS 1111300-43-6C16H19NO4S2
![3-{[(4-Isopropylphenyl)sulfonyl]amino}thiophene-2-carboxylic acid chemical structure, C14H15NO4S2, CAS 1111301-77-9](/s/JYRORHOEQDBFGG-UHFFFAOYSA-N.svg)
3-{[(4-Isopropylphenyl)sulfonyl]amino}thiophene-2-carboxylic acid
CAS 1111301-77-9C14H15NO4S2
![Methyl 3-[[(3-amino-2-methylphenyl)sulfonyl]amino]-2-thiophenecarboxylate chemical structure, C13H14N2O4S2, CAS 1038729-37-1](/s/BQGIAHBUHNFPPW-UHFFFAOYSA-N.svg)
Methyl 3-[[(3-amino-2-methylphenyl)sulfonyl]amino]-2-thiophenecarboxylate
CAS 1038729-37-1C13H14N2O4S2
![3-{[(4-Propylphenyl)sulfonyl]amino}thiophene-2-carboxylic acid chemical structure, C14H15NO4S2, CAS 1153238-87-9](/s/XKOUFSNMMOVZFU-UHFFFAOYSA-N.svg)
3-{[(4-Propylphenyl)sulfonyl]amino}thiophene-2-carboxylic acid
CAS 1153238-87-9C14H15NO4S2
- 3-(2,4,6-Trimethylbenzenesulfonamido)thiophene-2-carboxylic acid1153238-91-5C14H15NO4S2
- 3-[[(3,5-Dichlorophenyl)sulfonyl]amino]-2-thiophenecarboxylic acid1153028-62-6C11H7Cl2NO4S2
- 3-{[(3,4-Dimethylphenyl)sulfonyl]amino}thiophene-2-carboxylic acid1153392-73-4C13H13NO4S2
- 3-(4-tert-Butylbenzenesulfonamido)thiophene-2-carboxylic acid1111300-51-6C15H17NO4S2
- 3-(N-Methylbenzenesulfonamido)-N-pentylthiophene-2-carboxamide1116082-45-1C17H22N2O3S2
- N-(3-Methylbutyl)-3-[methyl(phenylsulfonyl)amino]thiophene-2-carboxamide1115933-45-3C17H22N2O3S2
- N-Butyl-3-(N-methylbenzenesulfonamido)thiophene-2-carboxamide1116017-30-1C16H20N2O3S2
- 3-(N-Methyl4-methoxybenzenesulfonamido)-N-propylthiophene-2-carboxamide1115871-59-4C16H20N2O4S2
- N-(4-Chlorobenzyl)-4-[6-(2-methoxyphenoxy)pyrimidin-4-yl]benzamide1116082-57-5C17H22N2O4S2
- N-(2,5-Dimethylphenyl)-N'-[3-(1H-indol-2-yl)phenyl]urea1115933-56-6C17H22N2O4S2
- 3-{[(4-Methoxyphenyl)sulfonyl](methyl)amino}-N-(prop-2-en-1-yl)thiophene-2-carboxamide1115871-60-7C16H18N2O4S2
- N-Butyl-3-(N-methyl4-methoxybenzenesulfonamido)thiophene-2-carboxamide1116082-59-7C17H22N2O4S2
- Methyl 2-{[3-(N-methyl4-chlorobenzenesulfonamido)thiophen-2-yl]formamido}acetate1251549-87-7C15H15ClN2O5S2
- N-Butyl-3-(N-methyl3-chloro-4-methylbenzenesulfonamido)thiophene-2-carboxamide1251605-04-5C17H21ClN2O3S2
- N-Ethyl-3-(N-methyl3-chloro-4-methylbenzenesulfonamido)thiophene-2-carboxamide1251625-30-5C15H17ClN2O3S2
- N-Allyl-3-(N-ethylphenylsulfonamido)thiophene-2-carboxamide1251605-98-7C16H18N2O3S2
- 3-(4-Methoxy-N-methylphenylsulfonamido)-N-methylthiophene-2-carboxamide1251549-32-2C14H16N2O4S2
- 3-(N-Methyl4-methylbenzenesulfonamido)-N-(2-methylpropyl)thiophene-2-carboxamide1226442-15-4C17H22N2O3S2
- 3-{[(4-Ethylphenyl)sulfonyl](methyl)amino}thiophene-2-carboxylic acid1291486-63-9C14H15NO4S2
- 3-(N-Methyl4-fluorobenzenesulfonamido)thiophene-2-carboxylic acid1291486-61-7C12H10FNO4S2
- 3-{[(4-Bromophenyl)sulfonyl](methyl)amino}thiophene-2-carboxylic acid1291486-57-1C12H10BrNO4S2
- Methyl 3-(methyl{[4-(propan-2-yl)phenyl]sulfonyl}amino)thiophene-2-carboxylate1325304-90-2C16H19NO4S2
- 3-{[(3-Chloro-4-methylphenyl)sulfonyl]amino}thiophene-2-carboxylic acid1325304-03-7C12H10ClNO4S2
- 3-{Methyl[(2,4,6-trimethylphenyl)sulfonyl]amino}thiophene-2-carboxylic acid1325306-81-7C15H17NO4S2
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1ccccc1)c1ccco1208 chemicals
O=C(Nc1ccccc1)c1cccs1150 chemicals
O=C(Nc1nccs1)c1ccccc1121 chemicals![Scaffold O=C(N=c1[nH]ncs1)c1ccccc1](/scaffold/RWOUBULBQYRRNL-UHFFFAOYSA-N/structure.svg)
O=C(N=c1[nH]ncs1)c1ccccc187 chemicals
c1ccc(OCc2ccco2)cc175 chemicals
O=S(=O)(Nc1nccs1)c1ccccc161 chemicals![Scaffold c1ccc(CSc2ncn[nH]2)cc1](/scaffold/IQQYSQRJFHUASD-UHFFFAOYSA-N/structure.svg)
c1ccc(CSc2ncn[nH]2)cc160 chemicals![Scaffold O=C(Nc1ccccc1)c1cc[nH]n1](/scaffold/WMZYZYFPPQOFKY-UHFFFAOYSA-N/structure.svg)
O=C(Nc1ccccc1)c1cc[nH]n160 chemicals
O=C(Nc1cccs1)c1ccccc152 chemicals
O=C(Nc1ccccc1)C1CCCO150 chemicals
O=C(Nc1ccccc1)c1ccoc148 chemicals
c1ccc(CSc2nncs2)cc144 chemicals