Murcko scaffold
Thieno[2,3-b]thiophene scaffold
82 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 8
- Chemicals
- 82
- With full pages
- 12
Scaffold SMILES
c1cc2ccsc2s1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 82 chemicals
![Thieno[2,3-b]thiophene chemical structure, C6H4S2, CAS 250-84-0](/s/YHBTXTFFTYXOFV-UHFFFAOYSA-N.svg)
Thieno[2,3-b]thiophene
CAS 250-84-0C6H4S2
Thieno(2,3-b)thiophene, 3-methyl-
CAS 1723-34-8C7H6S2
Thieno(2,3-b)thiophene, 2-bromo-
CAS 25121-81-7C6H3BrS2
Thieno(2,3-b)thiophene, 3-bromo-
CAS 25121-84-0C6H3BrS2
Thieno(2,3-b)thiophene, 2,5-dibromo-
CAS 25121-86-2C6H2Br2S2
Thieno(2,3-b)thiophene, 2-iodo-
CAS 53020-10-3C6H3IS2
Thieno(2,3-b)thiophene, 3-iodo-
CAS 53020-11-4C6H3IS2
Thieno(2,3-b)thiophene, 3,4-dibromo-
CAS 53255-78-0C6H2Br2S2
Thieno(2,3-b)thiophene, 2,3,4-tribromo-
CAS 53255-84-8C6HBr3S2
Thieno(2,3-b)thiophene,2,3,5-tribromo-
CAS 53255-85-9C6HBr3S2
Thieno(2,3-b)thiophene, 2,3,4,5-tetrabromo-
CAS 53255-86-0C6Br4S2
5-(((Methoxyethyl)((methoxyethoxy)ethyl)amino)methyl)thieno(2,3-b)thiophene-2-sulfonamide
CAS 128620-92-8C15H24N2O5S3
![5-Methylsulfanylthieno[2,3-b]thiophene chemical structure, C7H6S3, CAS 40985-55-5](/s/WDPWMRMGXRTQEF-UHFFFAOYSA-N.svg)
5-Methylsulfanylthieno[2,3-b]thiophene
CAS 40985-55-5C7H6S3
![3,4-Diaminothieno[2,3-b]thiophene-2,5-dicarbonitrile chemical structure, C8H4N4S2, CAS 3954-26-5](/s/KZBSENMHTIDEHV-UHFFFAOYSA-N.svg)
3,4-Diaminothieno[2,3-b]thiophene-2,5-dicarbonitrile
CAS 3954-26-5C8H4N4S2
Diethyl 3,4-dimethylthieno(2,3-b)thiophene-2,5-dicarboxylate
CAS 152487-69-9C14H16O4S2
![2,4-Dibromothieno[2,3-b]thiophene chemical structure, C6H2Br2S2, CAS 25121-85-1](/s/APGVLNZLGUAMKO-UHFFFAOYSA-N.svg)
2,4-Dibromothieno[2,3-b]thiophene
CAS 25121-85-1C6H2Br2S2
![Thieno[2,3-b]thiophene-2,5-dicarboxylic acid chemical structure, C8H4O4S2, CAS 18647-18-2](/s/ISQJBPFNAXXTCB-UHFFFAOYSA-N.svg)
Thieno[2,3-b]thiophene-2,5-dicarboxylic acid
CAS 18647-18-2C8H4O4S2
![3-Methylthieno[2,3-b]thiophene-2-carboxylic acid chemical structure, C8H6O2S2, CAS 31490-65-0](/s/RGONASJZKXPGFL-UHFFFAOYSA-N.svg)
3-Methylthieno[2,3-b]thiophene-2-carboxylic acid
CAS 31490-65-0C8H6O2S2
![Ethyl 5-acetyl-3-hydroxy-4-methylthieno[2,3-b]thiophene-2-carboxylate chemical structure, C12H12O4S2, CAS 555154-27-3](/s/AHLOHMBMWUCMBZ-UHFFFAOYSA-N.svg)
Ethyl 5-acetyl-3-hydroxy-4-methylthieno[2,3-b]thiophene-2-carboxylate
CAS 555154-27-3C12H12O4S2
![1-(3,4-Dimethylthieno[2,3-B]thiophen-2-yl)ethan-1-one chemical structure, C10H10OS2, CAS 306935-22-8](/s/NZUPKEIODOWCDZ-UHFFFAOYSA-N.svg)
1-(3,4-Dimethylthieno[2,3-B]thiophen-2-yl)ethan-1-one
CAS 306935-22-8C10H10OS2
Thieno(2,3-b)thiophene-2-carboxylic acid
CAS 14756-75-3C7H4O2S2
![Diethyl 3,4-diaminothieno[2,3-b]thiophene-2,5-dicarboxylate chemical structure, C12H14N2O4S2, CAS 4004-20-0](/s/FTGFURZVTLYXEX-UHFFFAOYSA-N.svg)
Diethyl 3,4-diaminothieno[2,3-b]thiophene-2,5-dicarboxylate
CAS 4004-20-0C12H14N2O4S2
![5-Cyano-3,4-diaminothieno[2,3-b]thiophene-2-carboxylic acid ethyl ester chemical structure, C10H9N3O2S2, CAS 148835-32-9](/s/IMTRPRVGIABPNK-UHFFFAOYSA-N.svg)
5-Cyano-3,4-diaminothieno[2,3-b]thiophene-2-carboxylic acid ethyl ester
CAS 148835-32-9C10H9N3O2S2
3,4-Dimethylthieno(2,3-b)thiophene-2,5-dicarboxylic acid
CAS 175202-55-8C10H8O4S2
- Ethyl 5-cyano-3,4-dimethylthieno[2,3-b]thiophene-2-carboxylate175202-57-0C12H11NO2S2
- 3,4-Dimethylthieno[2,3-B]thiophene-2-carbaldehyde159709-36-1C9H8OS2
- (3,4-Dimethylthieno[2,3-b]thiophen-2-yl)methanol175202-60-5C9H10OS2
- Methyl 3,4-dimethylthieno[2,3-b]thiophene-2-carboxylate175202-66-1C10H10O2S2
- 3,4-Dimethylthieno(2,3-b)thiophene175202-58-1C8H8S2
- 5-Acetyl-3,4-dimethylthieno[2,3-b]thiophene-2-carbonitrile845266-23-1C11H9NOS2
- 2,5-Dibromo-3,4-dimethylthieno[2,3-b]thiophene845778-61-2C8H6Br2S2
- Ethyl 5-acetyl-3,4-dimethylthieno[2,3-b]thiophene-2-carboxylate555154-25-1C13H14O3S2
- Thieno[2,3-b]thiophene-2-carboxylic acid, 5-acetyl-3,4-dimethyl-175602-09-2C11H10O3S2
- 1-(5-Bromo-3,4-dimethylthieno[2,3-b]thiophen-2-yl)ethanone210098-33-2C10H9BrOS2
- Thieno[2,3-b]thiophene-2-carboxaldehyde31486-85-8C7H4OS2
- 3-Chlorothieno[2,3-b]thiophene-2-carbonyl chloride39244-06-9C7H2Cl2OS2
- 3-Chlorothieno[2,3-b]thiophene-2-carboxylic acid39244-08-1C7H3ClO2S2
- Thieno[2,3-b]thiophene-2-carbonitrile40985-59-9C7H3NS2
- Diethyl thieno[2,3-b]thiophene-2,5-dicarboxylate398117-94-7C12H12O4S2
- 3,4-Dimethylthieno[2,3-b]thiophene-2,5-dicarbonitrile152487-70-2C10H6N2S2
- Methyl thieno[2,3-b]thiophene-2-carboxylate20969-37-3C8H6O2S2
- 2-Methylthieno[2,3-b]thiophene26238-22-2C7H6S2
- 2-{5-Methylthieno[2,3-b]thiophen-3-yl}acetic acid85504-38-7C9H8O2S2
- 2-{5-Ethylthieno[2,3-b]thiophen-3-yl}acetic acid85504-39-8C10H10O2S2
- Thieno[2,3-b]thiophene-2-methanol122267-21-4C7H6OS2
- 5-Methylaminomethyl-thieno[2,3-b]thiophene-2-sulfonic acid amide122266-89-1C8H10N2O2S3
- 5-[[(2-Hydroxyethyl)amino]methyl]thieno[2,3-b]thiophene-2-sulfonamide122266-93-7C9H12N2O3S3
- 5-[[(2-Methoxyethyl)amino]methyl]thieno[2,3-b]thiophene-2-sulfonamide122266-90-4C10H14N2O3S3
Related scaffolds
Same ring framework with different atoms or bond orders
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c1cn2c(n1)CCC236 chemicals
C1CC2OCCC2O129 chemicals
O=C1NC2CSCC2N129 chemicals![Scaffold c1[nH]nc2c1CCC2](/scaffold/TUVBJSPUCMUOSD-UHFFFAOYSA-N/structure.svg)
c1[nH]nc2c1CCC228 chemicals![Scaffold c1cc2sccc2[nH]1](/scaffold/DWAIOCIOSRZZHO-UHFFFAOYSA-N/structure.svg)
c1cc2sccc2[nH]125 chemicals
c1cc2sccc2s125 chemicals
C1CC2CCCN2C124 chemicals![Scaffold c1n[nH]c2c1CNC2](/scaffold/CVRWHBCQJCUBFE-UHFFFAOYSA-N/structure.svg)
c1n[nH]c2c1CNC223 chemicals