CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 17 atoms

13 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
13
With full pages
3
Scaffold SMILES

C(#Cc1cccc2[nH]cnc12)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(#Cc1cccc2[nH]cnc12)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

3-(2-(2-(2-Aminoethyl)-1H-1,3-benzodiazol-4-yl)ethynyl)benzamide dihydrochloride chemical structure, C18H18Cl2N4O, CAS 2731014-52-9
3-(2-(2-(2-Aminoethyl)-1H-1,3-benzodiazol-4-yl)ethynyl)benzamide dihydrochloride
CAS 2731014-52-9C18H18Cl2N4O
3-{2-[2-(2-Aminoethyl)-1H-1,3-benzodiazol-4-yl]ethynyl}benzamide chemical structure, C18H16N4O, CAS 2731014-51-8
3-{2-[2-(2-Aminoethyl)-1H-1,3-benzodiazol-4-yl]ethynyl}benzamide
CAS 2731014-51-8C18H16N4O
2-(7-(2-Phenylethynyl)-1H-1,3-benzodiazol-2-yl)ethan-1-amine dihydrochloride chemical structure, C17H17Cl2N3, CAS 2680533-96-2
2-(7-(2-Phenylethynyl)-1H-1,3-benzodiazol-2-yl)ethan-1-amine dihydrochloride
CAS 2680533-96-2C17H17Cl2N3
2-[7-(2-Phenylethynyl)-1H-1,3-benzodiazol-2-yl]ethan-1-amine chemical structure, C17H15N3, CAS 2529198-40-9
2-[7-(2-Phenylethynyl)-1H-1,3-benzodiazol-2-yl]ethan-1-amine
CAS 2529198-40-9C17H15N3
2-(4-(2-(3-Methoxyphenyl)ethynyl)-1H-1,3-benzodiazol-2-yl)ethan-1-amine dihydrochloride chemical structure, C18H19Cl2N3O, CAS 2703779-53-5
2-(4-(2-(3-Methoxyphenyl)ethynyl)-1H-1,3-benzodiazol-2-yl)ethan-1-amine dihydrochloride
CAS 2703779-53-5C18H19Cl2N3O
2-{4-[2-(3-Methoxyphenyl)ethynyl]-1H-1,3-benzodiazol-2-yl}ethan-1-amine chemical structure, C18H17N3O, CAS 2446014-01-1
2-{4-[2-(3-Methoxyphenyl)ethynyl]-1H-1,3-benzodiazol-2-yl}ethan-1-amine
CAS 2446014-01-1C18H17N3O
1-{4-[2-(3-Fluorophenyl)ethynyl]-1H-1,3-benzodiazol-2-yl}methanamine dihydrochloride chemical structure, C16H14Cl2FN3, CAS 2995288-77-0
1-{4-[2-(3-Fluorophenyl)ethynyl]-1H-1,3-benzodiazol-2-yl}methanamine dihydrochloride
CAS 2995288-77-0C16H14Cl2FN3
1-{4-[2-(4-Fluorophenyl)ethynyl]-1H-1,3-benzodiazol-2-yl}methanamine dihydrochloride chemical structure, C16H14Cl2FN3, CAS 2995298-80-9
1-{4-[2-(4-Fluorophenyl)ethynyl]-1H-1,3-benzodiazol-2-yl}methanamine dihydrochloride
CAS 2995298-80-9C16H14Cl2FN3
1-[7-(2-Phenylethynyl)-1H-1,3-benzodiazol-2-yl]methanamine dihydrochloride chemical structure, C16H15Cl2N3, CAS 2995291-89-7
1-[7-(2-Phenylethynyl)-1H-1,3-benzodiazol-2-yl]methanamine dihydrochloride
CAS 2995291-89-7C16H15Cl2N3
1-{4-[2-(4-Chlorophenyl)ethynyl]-1H-1,3-benzodiazol-2-yl}methanamine dihydrochloride chemical structure, C16H14Cl3N3, CAS 2995289-97-7
1-{4-[2-(4-Chlorophenyl)ethynyl]-1H-1,3-benzodiazol-2-yl}methanamine dihydrochloride
CAS 2995289-97-7C16H14Cl3N3
1-{4-[2-(3-Methoxyphenyl)ethynyl]-1H-1,3-benzodiazol-2-yl}methanamine dihydrochloride chemical structure, C17H17Cl2N3O, CAS 2995289-84-2
1-{4-[2-(3-Methoxyphenyl)ethynyl]-1H-1,3-benzodiazol-2-yl}methanamine dihydrochloride
CAS 2995289-84-2C17H17Cl2N3O
(4-((4-Methoxyphenyl)ethynyl)-1H-benzo[d]imidazol-2-yl)methanamine dihydrochloride chemical structure, C17H17Cl2N3O, CAS 2995289-88-6
(4-((4-Methoxyphenyl)ethynyl)-1H-benzo[d]imidazol-2-yl)methanamine dihydrochloride
CAS 2995289-88-6C17H17Cl2N3O
(4-((3-Chlorophenyl)ethynyl)-1H-benzo[d]imidazol-2-yl)methanamine dihydrochloride chemical structure, C16H14Cl3N3, CAS 2995274-15-0
(4-((3-Chlorophenyl)ethynyl)-1H-benzo[d]imidazol-2-yl)methanamine dihydrochloride
CAS 2995274-15-0C16H14Cl3N3