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Murcko scaffold

Ring system with 4 rings and 20 atoms

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
6
With full pages
1
Scaffold SMILES

O=C1OCCN1c1cn2c(n1)-c1ccccc1OCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1OCCN1c1cn2c(n1)-c1ccccc1OCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

(S)-3-(9-Bromo-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-2-yl)-4-(difluoromethyl)oxazolidin-2-one chemical structure, C15H12BrF2N3O3, CAS 2060571-10-8
(S)-3-(9-Bromo-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-2-yl)-4-(difluoromethyl)oxazolidin-2-one
CAS 2060571-10-8C15H12BrF2N3O3
Inavolisib chemical structure, C18H19F2N5O4, CAS 2060571-02-8
Inavolisib
CAS 2060571-02-8C18H19F2N5O4
Inavolisib impurity 3 chemical structure, C18H18F2N4O5, CAS 2230508-73-1
Inavolisib impurity 3
CAS 2230508-73-1C18H18F2N4O5
(2-((S)-4-(Difluoromethyl)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)-L-alanine, ammonia salt chemical structure, C18H21F2N5O5, CAS 2230508-74-2
(2-((S)-4-(Difluoromethyl)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)-L-alanine, ammonia salt
CAS 2230508-74-2C18H21F2N5O5
Inavolisib impurity 2 chemical structure, C15H14F2N4O3, CAS 2323538-39-0
Inavolisib impurity 2
CAS 2323538-39-0C15H14F2N4O3
Inavolisib impurity 4 chemical structure, C18H18F2N4O5, CAS 2323538-36-7
Inavolisib impurity 4
CAS 2323538-36-7C18H18F2N4O5