CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 26 atoms

43 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
43
With full pages
4
Scaffold SMILES

O=C(NCCc1ccncc1)OCC1c2ccccc2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCCc1ccncc1)OCC1c2ccccc2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 43 of 43 chemicals

(2S)-2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(pyridin-4-yl)propanoic acid chemical structure, C23H20N2O4, CAS 169555-95-7
(2S)-2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(pyridin-4-yl)propanoic acid
CAS 169555-95-7C23H20N2O4
Fmoc-D-4-Pyridylalanine chemical structure, C23H20N2O4, CAS 205528-30-9
Fmoc-D-4-Pyridylalanine
CAS 205528-30-9C23H20N2O4
Fmoc-(S)-3-amino-4-(4-pyridyl)-butyric acid chemical structure, C24H22N2O4, CAS 270065-69-5
Fmoc-(S)-3-amino-4-(4-pyridyl)-butyric acid
CAS 270065-69-5C24H22N2O4
2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(pyridin-4-yl)propanoic acid chemical structure, C23H20N2O4, CAS 746672-87-7
2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(pyridin-4-yl)propanoic acid
CAS 746672-87-7C23H20N2O4
Fmoc-(R)-3-amino-4-(4-pyridyl)-butyric acid chemical structure, C24H22N2O4, CAS 269396-69-2
Fmoc-(R)-3-amino-4-(4-pyridyl)-butyric acid
CAS 269396-69-2C24H22N2O4
(S)-4-[2-(Fmoc-amino)-2-carboxyethyl]pyridine 1-oxide chemical structure, C23H20N2O5, CAS 169555-96-8
(S)-4-[2-(Fmoc-amino)-2-carboxyethyl]pyridine 1-oxide
CAS 169555-96-8C23H20N2O5
3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-4-(pyridin-4-yl)butanoic acid chemical structure, C24H22N2O4, CAS 1823712-25-9
3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-4-(pyridin-4-yl)butanoic acid
CAS 1823712-25-9C24H22N2O4
(9H-Fluoren-9-yl)methyl N-[2-hydroxy-2-(pyridin-4-yl)ethyl]carbamate chemical structure, C22H20N2O3, CAS 1823244-47-8
(9H-Fluoren-9-yl)methyl N-[2-hydroxy-2-(pyridin-4-yl)ethyl]carbamate
CAS 1823244-47-8C22H20N2O3
Fmoc-L-4-Pal(2-Cl)-OH chemical structure, C23H19ClN2O4, CAS 1655518-64-1
Fmoc-L-4-Pal(2-Cl)-OH
CAS 1655518-64-1C23H19ClN2O4
3-(3-Chloropyridin-4-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C23H19ClN2O4, CAS 1379878-62-2
3-(3-Chloropyridin-4-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 1379878-62-2C23H19ClN2O4
3-(2-Chloropyridin-4-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C23H19ClN2O4, CAS 1379862-33-5
3-(2-Chloropyridin-4-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 1379862-33-5C23H19ClN2O4
Fmoc-L-3-(2-cyano-4-pyridyl)-alanine chemical structure, C24H19N3O4, CAS 2245755-79-5
Fmoc-L-3-(2-cyano-4-pyridyl)-alanine
CAS 2245755-79-5C24H19N3O4
2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-[2-(trifluoromethyl)pyridin-4-yl]propanoic acid chemical structure, C24H19F3N2O4, CAS 2418641-92-4
2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-[2-(trifluoromethyl)pyridin-4-yl]propanoic acid
CAS 2418641-92-4C24H19F3N2O4
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-(pyridin-4-yl)propanoic acid chemical structure, C24H22N2O4, CAS 2381854-90-4
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-(pyridin-4-yl)propanoic acid
CAS 2381854-90-4C24H22N2O4
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-fluoropyridin-4-yl)propanoic acid chemical structure, C23H19FN2O4, CAS 2349542-06-7
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-fluoropyridin-4-yl)propanoic acid
CAS 2349542-06-7C23H19FN2O4
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-chloropyridin-4-yl)propanoic acid chemical structure, C23H19ClN2O4, CAS 2350289-25-5
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-chloropyridin-4-yl)propanoic acid
CAS 2350289-25-5C23H19ClN2O4
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-hydroxy-3-(pyridin-4-yl)propanoic acid chemical structure, C23H20N2O5, CAS 2137482-27-8
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-hydroxy-3-(pyridin-4-yl)propanoic acid
CAS 2137482-27-8C23H20N2O5
3-[2-(Dimethylamino)pyridin-4-yl]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C25H25N3O4, CAS 2680549-27-1
3-[2-(Dimethylamino)pyridin-4-yl]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 2680549-27-1C25H25N3O4
Fmoc-N-Me-3-(4-Pyridyl)-D-alanine chemical structure, C24H22N2O4, CAS 2243125-97-3
Fmoc-N-Me-3-(4-Pyridyl)-D-alanine
CAS 2243125-97-3C24H22N2O4
4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(pyridin-4-yl)butanoic acid chemical structure, C24H22N2O4, CAS 2137652-12-9
4-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(pyridin-4-yl)butanoic acid
CAS 2137652-12-9C24H22N2O4
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(3-methylpyridin-4-yl)propanoic acid chemical structure, C24H22N2O4, CAS 1379864-10-4
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(3-methylpyridin-4-yl)propanoic acid
CAS 1379864-10-4C24H22N2O4
3-(2-Bromopyridin-4-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C23H19BrN2O4, CAS 1379831-85-2
3-(2-Bromopyridin-4-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 1379831-85-2C23H19BrN2O4
3-(3-Bromopyridin-4-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C23H19BrN2O4, CAS 1379831-45-4
3-(3-Bromopyridin-4-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 1379831-45-4C23H19BrN2O4
3-(3,5-Dichloropyridin-4-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C23H18Cl2N2O4, CAS 1379864-39-7
3-(3,5-Dichloropyridin-4-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 1379864-39-7C23H18Cl2N2O4