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Murcko scaffold

Ring system with 4 rings and 26 atoms

91 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
91
With full pages
2
Scaffold SMILES

O=C(NCCc1cccnc1)OCC1c2ccccc2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCCc1cccnc1)OCC1c2ccccc2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 91 chemicals

(2R)-2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(pyridin-3-yl)propanoic acid chemical structure, C23H20N2O4, CAS 142994-45-4
(2R)-2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(pyridin-3-yl)propanoic acid
CAS 142994-45-4C23H20N2O4
Fmoc-(S)-3-amino-4-(3-pyridyl)-butyric acid chemical structure, C24H22N2O4, CAS 270063-60-0
Fmoc-(S)-3-amino-4-(3-pyridyl)-butyric acid
CAS 270063-60-0C24H22N2O4
Fmoc-beta-(3-pyridyl)-Ala-OH chemical structure, C23H20N2O4, CAS 746672-88-8
Fmoc-beta-(3-pyridyl)-Ala-OH
CAS 746672-88-8C23H20N2O4
(2S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(pyridin-3-yl)propanoic acid chemical structure, C23H20N2O4, CAS 175453-07-3
(2S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(pyridin-3-yl)propanoic acid
CAS 175453-07-3C23H20N2O4
Fmoc-(R)-3-amino-4-(3-pyridyl)-butyric acid chemical structure, C24H22N2O4, CAS 269396-66-9
Fmoc-(R)-3-amino-4-(3-pyridyl)-butyric acid
CAS 269396-66-9C24H22N2O4
(9H-Fluoren-9-yl)methyl N-[2-hydroxy-2-(pyridin-3-yl)ethyl]carbamate chemical structure, C22H20N2O3, CAS 1822822-81-0
(9H-Fluoren-9-yl)methyl N-[2-hydroxy-2-(pyridin-3-yl)ethyl]carbamate
CAS 1822822-81-0C22H20N2O3
Fmoc-3-(6-bromo-3-pyridyl)-D-alanine chemical structure, C23H19BrN2O4, CAS 2349979-62-8
Fmoc-3-(6-bromo-3-pyridyl)-D-alanine
CAS 2349979-62-8C23H19BrN2O4
Fmoc-L-5-Pal(2-Me)-OH chemical structure, C24H22N2O4, CAS 1997435-75-2
Fmoc-L-5-Pal(2-Me)-OH
CAS 1997435-75-2C24H22N2O4
3-(6-Bromopyridin-3-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid chemical structure, C23H19BrN2O4, CAS 1379836-65-3
3-(6-Bromopyridin-3-yl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
CAS 1379836-65-3C23H19BrN2O4
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(6-methylpyridin-3-yl)propanoic acid chemical structure, C24H22N2O4, CAS 1698350-90-1
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(6-methylpyridin-3-yl)propanoic acid
CAS 1698350-90-1C24H22N2O4
Fmoc-3-(6-bromo-3-pyridyl)-L-alanine chemical structure, C23H19BrN2O4, CAS 916305-40-3
Fmoc-3-(6-bromo-3-pyridyl)-L-alanine
CAS 916305-40-3C23H19BrN2O4
2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(5-methylpyridin-3-yl)propanoic acid chemical structure, C24H22N2O4, CAS 1690487-99-0
2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(5-methylpyridin-3-yl)propanoic acid
CAS 1690487-99-0C24H22N2O4
Fmoc-3-(6-methoxy-3-pyridyl)-DL-alanine chemical structure, C24H22N2O5, CAS 1379836-53-9
Fmoc-3-(6-methoxy-3-pyridyl)-DL-alanine
CAS 1379836-53-9C24H22N2O5
a-(Fmoc-amino)-2-methoxy-3-pyridinepropanoic acid chemical structure, C24H22N2O5, CAS 1379832-78-6
a-(Fmoc-amino)-2-methoxy-3-pyridinepropanoic acid
CAS 1379832-78-6C24H22N2O5
3-(5-Bromopyridin-3-yl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid chemical structure, C23H19BrN2O4, CAS 1379844-78-6
3-(5-Bromopyridin-3-yl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
CAS 1379844-78-6C23H19BrN2O4
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(5-fluoropyridin-3-yl)propanoic acid chemical structure, C23H19FN2O4, CAS 1379878-83-7
2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(5-fluoropyridin-3-yl)propanoic acid
CAS 1379878-83-7C23H19FN2O4
Fmoc-3-(4-methyl-3-pyridyl)-DL-alanine chemical structure, C24H22N2O4, CAS 1691026-27-3
Fmoc-3-(4-methyl-3-pyridyl)-DL-alanine
CAS 1691026-27-3C24H22N2O4
Fmoc-L-5-Pal(2Cl)-OH chemical structure, C23H19ClN2O4, CAS 1241683-12-4
Fmoc-L-5-Pal(2Cl)-OH
CAS 1241683-12-4C23H19ClN2O4
Fmoc-3-(6-fluoro-3-pyridyl)-L-alanine chemical structure, C23H19FN2O4, CAS 1667753-66-3
Fmoc-3-(6-fluoro-3-pyridyl)-L-alanine
CAS 1667753-66-3C23H19FN2O4
Fmoc-3-(6-fluoro-3-pyridyl)-DL-alanine chemical structure, C23H19FN2O4, CAS 1379856-01-5
Fmoc-3-(6-fluoro-3-pyridyl)-DL-alanine
CAS 1379856-01-5C23H19FN2O4
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(6-methoxypyridin-3-yl)propanoic acid chemical structure, C24H22N2O5, CAS 1821775-88-5
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(6-methoxypyridin-3-yl)propanoic acid
CAS 1821775-88-5C24H22N2O5
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(6-cyanopyridin-3-yl)propanoic acid chemical structure, C24H19N3O4, CAS 2245755-80-8
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(6-cyanopyridin-3-yl)propanoic acid
CAS 2245755-80-8C24H19N3O4
Fmoc-3-(6-(dimethylamino)pyridin-3-yl)-Ala chemical structure, C25H25N3O4, CAS 2255321-22-1
Fmoc-3-(6-(dimethylamino)pyridin-3-yl)-Ala
CAS 2255321-22-1C25H25N3O4
(2S)-2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}(methyl)amino)-3-(pyridin-3-yl)propanoic acid chemical structure, C24H22N2O4, CAS 1979173-93-7
(2S)-2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}(methyl)amino)-3-(pyridin-3-yl)propanoic acid
CAS 1979173-93-7C24H22N2O4