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Murcko scaffold

2-(Pyrimidin-5-yl)pyrimidine scaffold

29 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
29
With full pages
3
Scaffold SMILES

c1cnc(-c2cncnc2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Pyrimidin-5-yl)pyrimidine page
Murcko scaffold c1cnc(-c2cncnc2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 29 of 29 chemicals

2-(Pyrimidin-5-yl)pyrimidine chemical structure, C8H6N4, CAS 87780-80-1
2-(Pyrimidin-5-yl)pyrimidine
CAS 87780-80-1C8H6N4
4-Chloro-6-methyl-2-(5-pyrimidyl)pyrimidine chemical structure, C9H7ClN4, CAS 1159815-81-2
4-Chloro-6-methyl-2-(5-pyrimidyl)pyrimidine
CAS 1159815-81-2C9H7ClN4
4-Amino-6-methyl-2-(5-pyrimidyl)pyrimidine chemical structure, C9H9N5, CAS 1159822-06-6
4-Amino-6-methyl-2-(5-pyrimidyl)pyrimidine
CAS 1159822-06-6C9H9N5
4-Chloro-6-bromo-2,5'-bipyrimidine chemical structure, C8H4BrClN4, CAS 1353855-07-8
4-Chloro-6-bromo-2,5'-bipyrimidine
CAS 1353855-07-8C8H4BrClN4
Methyl 2'-amino-6-methoxy[2,5'-bipyrimidine]-4-carboxylate chemical structure, C11H11N5O3, CAS 1244019-25-7
Methyl 2'-amino-6-methoxy[2,5'-bipyrimidine]-4-carboxylate
CAS 1244019-25-7C11H11N5O3
[2,5'-Bipyrimidine]-5-carbonitrile chemical structure, C9H5N5, CAS 1261236-47-8
[2,5'-Bipyrimidine]-5-carbonitrile
CAS 1261236-47-8C9H5N5
2-(Pyrimidin-5-yl)pyrimidine-4-carboxylic acid chemical structure, C9H6N4O2, CAS 1557023-06-9
2-(Pyrimidin-5-yl)pyrimidine-4-carboxylic acid
CAS 1557023-06-9C9H6N4O2
4'-Methyl-[2,5'-bipyrimidine]-4-carboxylic acid chemical structure, C10H8N4O2, CAS 1784266-45-0
4'-Methyl-[2,5'-bipyrimidine]-4-carboxylic acid
CAS 1784266-45-0C10H8N4O2
2-Methoxy-5-pyrimidin-2-ylpyrimidine chemical structure, C9H8N4O, CAS 696602-24-1
2-Methoxy-5-pyrimidin-2-ylpyrimidine
CAS 696602-24-1C9H8N4O
4-Amino-2-(pyrimidin-5-yl)pyrimidine chemical structure, C8H7N5, CAS 1595891-01-2
4-Amino-2-(pyrimidin-5-yl)pyrimidine
CAS 1595891-01-2C8H7N5
(2,5'-Bipyrimidin)-5-amine chemical structure, C8H7N5, CAS 1866300-19-7
(2,5'-Bipyrimidin)-5-amine
CAS 1866300-19-7C8H7N5
5-(Pyrimidin-2-yl)pyrimidin-2-amine chemical structure, C8H7N5, CAS 2167788-07-8
5-(Pyrimidin-2-yl)pyrimidin-2-amine
CAS 2167788-07-8C8H7N5
[2,5'-Bipyrimidine]-5-carbaldehyde chemical structure, C9H6N4O, CAS 1261236-71-8
[2,5'-Bipyrimidine]-5-carbaldehyde
CAS 1261236-71-8C9H6N4O
4-Amino-5-bromo-2-(pyrimidin-5-yl)pyrimidine chemical structure, C8H6BrN5, CAS 1563531-94-1
4-Amino-5-bromo-2-(pyrimidin-5-yl)pyrimidine
CAS 1563531-94-1C8H6BrN5
[2-(Pyrimidin-5-yl)pyrimidin-5-yl]methanol chemical structure, C9H8N4O, CAS 1934638-95-5
[2-(Pyrimidin-5-yl)pyrimidin-5-yl]methanol
CAS 1934638-95-5C9H8N4O
5-(Chloromethyl)-2,5'-bipyrimidine chemical structure, C9H7ClN4, CAS 1935639-29-4
5-(Chloromethyl)-2,5'-bipyrimidine
CAS 1935639-29-4C9H7ClN4
4-(Chloromethyl)-4'-methyl-2,5'-bipyrimidine chemical structure, C10H9ClN4, CAS 1935241-51-2
4-(Chloromethyl)-4'-methyl-2,5'-bipyrimidine
CAS 1935241-51-2C10H9ClN4
4,6-Dichloro-2,5'-bipyrimidine chemical structure, C8H4Cl2N4, CAS 1858039-72-1
4,6-Dichloro-2,5'-bipyrimidine
CAS 1858039-72-1C8H4Cl2N4
5-Bromo-4-chloro-2,5'-bipyrimidine chemical structure, C8H4BrClN4, CAS 1852636-43-1
5-Bromo-4-chloro-2,5'-bipyrimidine
CAS 1852636-43-1C8H4BrClN4
Sodium 2,5'-bipyrimidine-5-carboxylate chemical structure, C9H5N4NaO2, CAS 2197057-27-3
Sodium 2,5'-bipyrimidine-5-carboxylate
CAS 2197057-27-3C9H5N4NaO2
5-(Chloromethyl)-2-pyrimidin-5-ylpyrimidine, hydrochloride chemical structure, C9H8Cl2N4, CAS 2253631-89-7
5-(Chloromethyl)-2-pyrimidin-5-ylpyrimidine, hydrochloride
CAS 2253631-89-7C9H8Cl2N4
2'-Chloro-2,5'-bipyrimidine chemical structure, C8H5ClN4, CAS 2413178-37-5
2'-Chloro-2,5'-bipyrimidine
CAS 2413178-37-5C8H5ClN4
5-Methyl-2-(pyrimidin-5-yl)pyrimidine-4-carboxylic acid chemical structure, C10H8N4O2, CAS 2001339-65-5
5-Methyl-2-(pyrimidin-5-yl)pyrimidine-4-carboxylic acid
CAS 2001339-65-5C10H8N4O2
4-Methyl-[2,5'-bipyrimidine]-5-carboxylic acid chemical structure, C10H8N4O2, CAS 2007477-61-2
4-Methyl-[2,5'-bipyrimidine]-5-carboxylic acid
CAS 2007477-61-2C10H8N4O2