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Murcko scaffold

Piperidin-1-yl(thiophen-2-yl)methanone scaffold

164 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
164
With full pages
9
Scaffold SMILES

O=C(c1cccs1)N1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Piperidin-1-yl(thiophen-2-yl)methanone page
Murcko scaffold O=C(c1cccs1)N1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 164 chemicals

N-[3-Cyano-4-methyl-5-(1-piperidinylcarbonyl)-2-thienyl]-2,3,3,3-tetrafluoro-2-methoxypropanamide chemical structure, C16H17F4N3O3S, CAS 442629-94-9
N-[3-Cyano-4-methyl-5-(1-piperidinylcarbonyl)-2-thienyl]-2,3,3,3-tetrafluoro-2-methoxypropanamide
CAS 442629-94-9C16H17F4N3O3S
(4-Methylpiperidin-1-yl)-thiophen-2-ylmethanone chemical structure, C11H15NOS, CAS 296244-18-3
(4-Methylpiperidin-1-yl)-thiophen-2-ylmethanone
CAS 296244-18-3C11H15NOS
Piperidin-1-yl(thiophen-2-yl)methanone chemical structure, C10H13NOS, CAS 31330-58-2
Piperidin-1-yl(thiophen-2-yl)methanone
CAS 31330-58-2C10H13NOS
2-Amino-4-methyl-5-(piperidin-1-ylcarbonyl)thiophene-3-carbonitrile chemical structure, C12H15N3OS, CAS 313971-49-2
2-Amino-4-methyl-5-(piperidin-1-ylcarbonyl)thiophene-3-carbonitrile
CAS 313971-49-2C12H15N3OS
Ethyl 2-amino-4-methyl-5-(piperidine-1-carbonyl)thiophene-3-carboxylate chemical structure, C14H20N2O3S, CAS 297182-53-7
Ethyl 2-amino-4-methyl-5-(piperidine-1-carbonyl)thiophene-3-carboxylate
CAS 297182-53-7C14H20N2O3S
Ethyl 1-(2-thienylcarbonyl)-4-piperidinecarboxylate chemical structure, C13H17NO3S, CAS 307524-34-1
Ethyl 1-(2-thienylcarbonyl)-4-piperidinecarboxylate
CAS 307524-34-1C13H17NO3S
1-(Thiophene-2-carbonyl)-piperidine-4-carboxylic acid chemical structure, C11H13NO3S, CAS 147636-34-8
1-(Thiophene-2-carbonyl)-piperidine-4-carboxylic acid
CAS 147636-34-8C11H13NO3S
N-Methyl-1-(thiophene-2-carbonyl)piperidine-4-carboxamide chemical structure, C12H16N2O2S, CAS 797813-63-9
N-Methyl-1-(thiophene-2-carbonyl)piperidine-4-carboxamide
CAS 797813-63-9C12H16N2O2S
tert-Butyl (1-(thiophene-2-carbonyl)piperidin-4-yl)carbamate chemical structure, C15H22N2O3S, CAS 651292-83-0
tert-Butyl (1-(thiophene-2-carbonyl)piperidin-4-yl)carbamate
CAS 651292-83-0C15H22N2O3S
(2-Ethylpiperidin-1-yl)-thiophen-2-ylmethanone chemical structure, C12H17NOS, CAS 315672-38-9
(2-Ethylpiperidin-1-yl)-thiophen-2-ylmethanone
CAS 315672-38-9C12H17NOS
Ethyl 2-amino-5-(3-carbamoylpiperidine-1-carbonyl)-4-methylthiophene-3-carboxylate chemical structure, C15H21N3O4S, CAS 5787-75-7
Ethyl 2-amino-5-(3-carbamoylpiperidine-1-carbonyl)-4-methylthiophene-3-carboxylate
CAS 5787-75-7C15H21N3O4S
Ethyl 1-(2-thienylcarbonyl)-3-piperidinecarboxylate chemical structure, C13H17NO3S, CAS 310454-56-9
Ethyl 1-(2-thienylcarbonyl)-3-piperidinecarboxylate
CAS 310454-56-9C13H17NO3S
Methyl 4-methyl-2-[(2-methylpropanoyl)amino]-5-(piperidin-1-ylcarbonyl)thiophene-3-carboxylate chemical structure, C17H24N2O4S, CAS 832124-84-2
Methyl 4-methyl-2-[(2-methylpropanoyl)amino]-5-(piperidin-1-ylcarbonyl)thiophene-3-carboxylate
CAS 832124-84-2C17H24N2O4S
1-(Thiophene-2-carbonyl)piperidine-3-carboxylic acid chemical structure, C11H13NO3S, CAS 436093-08-2
1-(Thiophene-2-carbonyl)piperidine-3-carboxylic acid
CAS 436093-08-2C11H13NO3S
(3-(Hydroxymethyl)piperidin-1-yl)(thiophen-2-yl)methanone chemical structure, C11H15NO2S, CAS 349097-58-1
(3-(Hydroxymethyl)piperidin-1-yl)(thiophen-2-yl)methanone
CAS 349097-58-1C11H15NO2S
2-Methylpiperidyl 2-thienyl ketone chemical structure, C11H15NOS, CAS 346694-86-8
2-Methylpiperidyl 2-thienyl ketone
CAS 346694-86-8C11H15NOS
Methyl 1-(thiophene-2-carbonyl)piperidine-4-carboxylate chemical structure, C12H15NO3S, CAS 349620-26-4
Methyl 1-(thiophene-2-carbonyl)piperidine-4-carboxylate
CAS 349620-26-4C12H15NO3S
(4-Bromo-5-propylthiophen-2-yl)(2-ethylpiperidin-1-yl)methanone chemical structure, C15H22BrNOS, CAS 588676-75-9
(4-Bromo-5-propylthiophen-2-yl)(2-ethylpiperidin-1-yl)methanone
CAS 588676-75-9C15H22BrNOS
(4-Aminopiperidin-1-yl)(thiophen-2-yl)methanone chemical structure, C10H14N2OS, CAS 886497-83-2
(4-Aminopiperidin-1-yl)(thiophen-2-yl)methanone
CAS 886497-83-2C10H14N2OS
(2-(Hydroxymethyl)piperidin-1-yl)(thiophen-2-yl)methanone chemical structure, C11H15NO2S, CAS 349097-60-5
(2-(Hydroxymethyl)piperidin-1-yl)(thiophen-2-yl)methanone
CAS 349097-60-5C11H15NO2S
1-(4,5-Dibromothiophene-2-carbonyl)piperidine-4-carboxamide chemical structure, C11H12Br2N2O2S, CAS 870769-18-9
1-(4,5-Dibromothiophene-2-carbonyl)piperidine-4-carboxamide
CAS 870769-18-9C11H12Br2N2O2S
1-(Thiophene-2-carbonyl)piperidine-2-carboxylic acid chemical structure, C11H13NO3S, CAS 1032056-92-0
1-(Thiophene-2-carbonyl)piperidine-2-carboxylic acid
CAS 1032056-92-0C11H13NO3S
1-(5-Bromothiophene-2-carbonyl)piperidine-2-carboxamide chemical structure, C11H13BrN2O2S, CAS 1008409-87-7
1-(5-Bromothiophene-2-carbonyl)piperidine-2-carboxamide
CAS 1008409-87-7C11H13BrN2O2S
(4-Aminopiperidin-1-yl)(thiophen-2-yl)methanone hydrochloride chemical structure, C10H15ClN2OS, CAS 1158299-69-4
(4-Aminopiperidin-1-yl)(thiophen-2-yl)methanone hydrochloride
CAS 1158299-69-4C10H15ClN2OS