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Murcko scaffold

Ring system with 4 rings and 23 atoms

13 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
13
With full pages
8
Scaffold SMILES

O=C1c2ccccc2NC(c2ccccc2)N1Cc1ccco1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1c2ccccc2NC(c2ccccc2)N1Cc1ccco1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

3-(Furan-2-ylmethyl)-2-(4-methylphenyl)-1,2-dihydroquinazolin-4-one chemical structure, C20H18N2O2, CAS 404932-70-3
3-(Furan-2-ylmethyl)-2-(4-methylphenyl)-1,2-dihydroquinazolin-4-one
CAS 404932-70-3C20H18N2O2
2-(3,4-Dimethoxyphenyl)-3-(furan-2-ylmethyl)-1,2-dihydroquinazolin-4-one chemical structure, C21H20N2O4, CAS 381192-27-4
2-(3,4-Dimethoxyphenyl)-3-(furan-2-ylmethyl)-1,2-dihydroquinazolin-4-one
CAS 381192-27-4C21H20N2O4
3-(Furan-2-ylmethyl)-2-(3,4,5-trimethoxyphenyl)-1,2-dihydroquinazolin-4-one chemical structure, C22H22N2O5, CAS 312627-06-8
3-(Furan-2-ylmethyl)-2-(3,4,5-trimethoxyphenyl)-1,2-dihydroquinazolin-4-one
CAS 312627-06-8C22H22N2O5
3-(Furan-2-ylmethyl)-2-(4-hydroxyphenyl)-1,2-dihydroquinazolin-4-one chemical structure, C19H16N2O3, CAS 312627-07-9
3-(Furan-2-ylmethyl)-2-(4-hydroxyphenyl)-1,2-dihydroquinazolin-4-one
CAS 312627-07-9C19H16N2O3
2-(3,4-Dichlorophenyl)-3-(furan-2-ylmethyl)-2,3-dihydroquinazolin-4(1H)-one chemical structure, C19H14Cl2N2O2, CAS 352660-64-1
2-(3,4-Dichlorophenyl)-3-(furan-2-ylmethyl)-2,3-dihydroquinazolin-4(1H)-one
CAS 352660-64-1C19H14Cl2N2O2
2-(2,4-Dichlorophenyl)-3-(furan-2-ylmethyl)-2,3-dihydroquinazolin-4(1H)-one chemical structure, C19H14Cl2N2O2, CAS 383372-82-5
2-(2,4-Dichlorophenyl)-3-(furan-2-ylmethyl)-2,3-dihydroquinazolin-4(1H)-one
CAS 383372-82-5C19H14Cl2N2O2
2-(4-Bromophenyl)-3-(furan-2-ylmethyl)-1,2-dihydroquinazolin-4-one chemical structure, C19H15BrN2O2, CAS 375840-38-3
2-(4-Bromophenyl)-3-(furan-2-ylmethyl)-1,2-dihydroquinazolin-4-one
CAS 375840-38-3C19H15BrN2O2
2-(2-Fluorophenyl)-3-(furan-2-ylmethyl)-1,2-dihydroquinazolin-4-one chemical structure, C19H15FN2O2, CAS 404932-75-8
2-(2-Fluorophenyl)-3-(furan-2-ylmethyl)-1,2-dihydroquinazolin-4-one
CAS 404932-75-8C19H15FN2O2
2-(3-Fluorophenyl)-3-(furan-2-ylmethyl)-1,2-dihydroquinazolin-4-one chemical structure, C19H15FN2O2, CAS 335206-48-9
2-(3-Fluorophenyl)-3-(furan-2-ylmethyl)-1,2-dihydroquinazolin-4-one
CAS 335206-48-9C19H15FN2O2
2-(3-Ethoxy-4-hydroxyphenyl)-3-(furan-2-ylmethyl)-1,2-dihydroquinazolin-4-one chemical structure, C21H20N2O4, CAS 375353-52-9
2-(3-Ethoxy-4-hydroxyphenyl)-3-(furan-2-ylmethyl)-1,2-dihydroquinazolin-4-one
CAS 375353-52-9C21H20N2O4
3-(Furan-2-ylmethyl)-2-(2-hydroxyphenyl)-1,2-dihydroquinazolin-4-one chemical structure, C19H16N2O3, CAS 352660-65-2
3-(Furan-2-ylmethyl)-2-(2-hydroxyphenyl)-1,2-dihydroquinazolin-4-one
CAS 352660-65-2C19H16N2O3
2-(2,6-Dichlorophenyl)-3-(furan-2-ylmethyl)-2,3-dihydroquinazolin-4(1H)-one chemical structure, C19H14Cl2N2O2, CAS 6146-85-6
2-(2,6-Dichlorophenyl)-3-(furan-2-ylmethyl)-2,3-dihydroquinazolin-4(1H)-one
CAS 6146-85-6C19H14Cl2N2O2
3-[(Furan-2-yl)methyl]-2-(3-hydroxyphenyl)-2,3-dihydroquinazolin-4(1H)-one chemical structure, C19H16N2O3, CAS 6142-69-4
3-[(Furan-2-yl)methyl]-2-(3-hydroxyphenyl)-2,3-dihydroquinazolin-4(1H)-one
CAS 6142-69-4C19H16N2O3