CompoundList
Sign in
Murcko scaffold

5,6,7,7a-Tetrahydro-2(4H)-benzofuranone scaffold

30 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
30
With full pages
9
Scaffold SMILES

O=C1C=C2CCCCC2O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5,6,7,7a-Tetrahydro-2(4H)-benzofuranone page
Murcko scaffold O=C1C=C2CCCCC2O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 30 of 30 chemicals

6-Hydroxy-4,4,7a-trimethyl-5,6,7,7a-tetrahydro-1-benzofuran-2(4H)-one chemical structure, C11H16O3, CAS 1133-03-5
6-Hydroxy-4,4,7a-trimethyl-5,6,7,7a-tetrahydro-1-benzofuran-2(4H)-one
CAS 1133-03-5C11H16O3
(±)-Dihydroactinidiolide chemical structure, C11H16O2, CAS 15356-74-8
(±)-Dihydroactinidiolide
CAS 15356-74-8C11H16O2
Menthalactone chemical structure, C10H14O2, CAS 13341-72-5
Menthalactone
CAS 13341-72-5C10H14O2
Loliolide chemical structure, C11H16O3, CAS 5989-02-6
Loliolide
CAS 5989-02-6C11H16O3
3,6-Dimethyl-7a-hydroxy-5,6,7,7a-tetrahydrobenzofuran-2(4H)-one chemical structure, C10H14O3, CAS 514-93-2
3,6-Dimethyl-7a-hydroxy-5,6,7,7a-tetrahydrobenzofuran-2(4H)-one
CAS 514-93-2C10H14O3
Dihydroactinidiolide, (+)- chemical structure, C11H16O2, CAS 81800-41-1
Dihydroactinidiolide, (+)-
CAS 81800-41-1C11H16O2
7a-Hydroxy-3-methyl-5,6,7,7a-tetrahydro-1-benzofuran-2(4H)-one chemical structure, C9H12O3, CAS 15210-14-7
7a-Hydroxy-3-methyl-5,6,7,7a-tetrahydro-1-benzofuran-2(4H)-one
CAS 15210-14-7C9H12O3
1,2-Dihydroxymint lactone chemical structure, C10H14O4, CAS 168029-69-4
1,2-Dihydroxymint lactone
CAS 168029-69-4C10H14O4
Deoxysericealactone chemical structure, C16H20O4, CAS 19892-19-4
Deoxysericealactone
CAS 19892-19-4C16H20O4
Methyl 2-(6-ethenyl-7a-hydroxy-3,6-dimethyl-2-oxo-5,7-dihydro-4H-1-benzofuran-5-yl)prop-2-enoate chemical structure, C16H20O5, CAS 19892-18-3
Methyl 2-(6-ethenyl-7a-hydroxy-3,6-dimethyl-2-oxo-5,7-dihydro-4H-1-benzofuran-5-yl)prop-2-enoate
CAS 19892-18-3C16H20O5
(-)-Mintlactone chemical structure, C10H14O2, CAS 38049-04-6
(-)-Mintlactone
CAS 38049-04-6C10H14O2
Isomintlactone chemical structure, C10H14O2, CAS 75684-66-1
Isomintlactone
CAS 75684-66-1C10H14O2
Dihydroactinidiolide chemical structure, C11H16O2, CAS 17092-92-1
Dihydroactinidiolide
CAS 17092-92-1C11H16O2
Mintlactone, (+)- chemical structure, C10H14O2, CAS 166584-27-6
Mintlactone, (+)-
CAS 166584-27-6C10H14O2
(6S,7aS)-5,6,7,7a-Tetrahydro-6-hydroxy-4,4,7a-trimethyl-2(4H)-benzofuranone chemical structure, C11H16O3, CAS 38274-00-9
(6S,7aS)-5,6,7,7a-Tetrahydro-6-hydroxy-4,4,7a-trimethyl-2(4H)-benzofuranone
CAS 38274-00-9C11H16O3
Isomintlactone,(-)- chemical structure, C10H14O2, CAS 208841-46-7
Isomintlactone,(-)-
CAS 208841-46-7C10H14O2
2(4H)-Benzofuranone, 7a-chloro-5,6,7,7a-tetrahydro-3-methyl- chemical structure, C9H11ClO2, CAS 591231-54-8
2(4H)-Benzofuranone, 7a-chloro-5,6,7,7a-tetrahydro-3-methyl-
CAS 591231-54-8C9H11ClO2
5,6,7,7a-Tetrahydro-2(4H)-benzofuranone chemical structure, C8H10O2, CAS 6051-17-8
5,6,7,7a-Tetrahydro-2(4H)-benzofuranone
CAS 6051-17-8C8H10O2
2(4H)-Benzofuranone, 3-ethyl-5,6,7,7a-tetrahydro- chemical structure, C10H14O2, CAS 55229-19-1
2(4H)-Benzofuranone, 3-ethyl-5,6,7,7a-tetrahydro-
CAS 55229-19-1C10H14O2
2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-3-pentyl- chemical structure, C13H20O2, CAS 55229-18-0
2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-3-pentyl-
CAS 55229-18-0C13H20O2
Isocalendin chemical structure, C11H16O3, CAS 10481-90-0
Isocalendin
CAS 10481-90-0C11H16O3
(7R,7aR)-3,5,5,7-Tetramethyl-5,6,7,7a-tetrahydro-1-benzofuran-2(4H)-one chemical structure, C12H18O2, CAS 65745-56-4
(7R,7aR)-3,5,5,7-Tetramethyl-5,6,7,7a-tetrahydro-1-benzofuran-2(4H)-one
CAS 65745-56-4C12H18O2
7-Hydroxy-5,5,7-trimethyl-5,6,7,7a-tetrahydro-1-benzofuran-2(4H)-one chemical structure, C11H16O3, CAS 61173-73-7
7-Hydroxy-5,5,7-trimethyl-5,6,7,7a-tetrahydro-1-benzofuran-2(4H)-one
CAS 61173-73-7C11H16O3
3,4-Dimethyl-5,6,7,7a-tetrahydro-1-benzofuran-2(4H)-one chemical structure, C10H14O2, CAS 74795-76-9
3,4-Dimethyl-5,6,7,7a-tetrahydro-1-benzofuran-2(4H)-one
CAS 74795-76-9C10H14O2