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Murcko scaffold

2-(2-Pyridinyl)quinoline scaffold

109 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
109
With full pages
6
Scaffold SMILES

c1ccc(-c2ccc3ccccc3n2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(2-Pyridinyl)quinoline page
Murcko scaffold c1ccc(-c2ccc3ccccc3n2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 109 chemicals

Cinchoninic acid, 6-methyl-2-(2-pyridyl)- chemical structure, C16H12N2O2, CAS 5110-01-0
Cinchoninic acid, 6-methyl-2-(2-pyridyl)-
CAS 5110-01-0C16H12N2O2
2-(Pyridin-2-yl)quinoline-4-carboxylic acid chemical structure, C15H10N2O2, CAS 57882-27-6
2-(Pyridin-2-yl)quinoline-4-carboxylic acid
CAS 57882-27-6C15H10N2O2
Ethyl 2-(pyridin-2-yl)quinoline-4-carboxylate chemical structure, C17H14N2O2, CAS 5110-06-5
Ethyl 2-(pyridin-2-yl)quinoline-4-carboxylate
CAS 5110-06-5C17H14N2O2
N-[2-(Dimethylamino)ethyl]-2-(2-pyridyl)quinolin-4-amine chemical structure, C18H20N4, CAS 133671-55-3
N-[2-(Dimethylamino)ethyl]-2-(2-pyridyl)quinolin-4-amine
CAS 133671-55-3C18H20N4
N-[2-(Dimethylamino)ethyl]-N-ethyl-2-(2-pyridyl)-quinolin-4-amine chemical structure, C20H24N4, CAS 133671-56-4
N-[2-(Dimethylamino)ethyl]-N-ethyl-2-(2-pyridyl)-quinolin-4-amine
CAS 133671-56-4C20H24N4
4-Quinolinamine, 2-(2-pyridinyl)- chemical structure, C14H11N3, CAS 122664-09-9
4-Quinolinamine, 2-(2-pyridinyl)-
CAS 122664-09-9C14H11N3
2-(2-Pyridinyl)quinoline chemical structure, C14H10N2, CAS 7491-86-3
2-(2-Pyridinyl)quinoline
CAS 7491-86-3C14H10N2
6-Bromo-2-pyridin-2-ylquinoline-4-carboxylic acid chemical structure, C15H9BrN2O2, CAS 5109-98-8
6-Bromo-2-pyridin-2-ylquinoline-4-carboxylic acid
CAS 5109-98-8C15H9BrN2O2
6-Bromo-2-pyridin-2-ylquinoline-4-carboxamide chemical structure, C15H10BrN3O, CAS 713114-81-9
6-Bromo-2-pyridin-2-ylquinoline-4-carboxamide
CAS 713114-81-9C15H10BrN3O
6-Chloro-2-pyridin-2-ylquinoline-4-carboxamide chemical structure, C15H10ClN3O, CAS 713119-26-7
6-Chloro-2-pyridin-2-ylquinoline-4-carboxamide
CAS 713119-26-7C15H10ClN3O
6-Ethyl-2-pyridin-2-ylquinoline-4-carboxylic acid chemical structure, C17H14N2O2, CAS 588711-28-8
6-Ethyl-2-pyridin-2-ylquinoline-4-carboxylic acid
CAS 588711-28-8C17H14N2O2
8-Ethyl-2-pyridin-2-ylquinoline-4-carboxylic acid chemical structure, C17H14N2O2, CAS 726144-14-5
8-Ethyl-2-pyridin-2-ylquinoline-4-carboxylic acid
CAS 726144-14-5C17H14N2O2
2-Pyridin-2-ylquinoline-4-carbohydrazide chemical structure, C15H12N4O, CAS 5109-96-6
2-Pyridin-2-ylquinoline-4-carbohydrazide
CAS 5109-96-6C15H12N4O
Sodium 2-(pyridin-2-yl)quinoline-4-carboxylate chemical structure, C15H9N2NaO2, CAS 190895-01-3
Sodium 2-(pyridin-2-yl)quinoline-4-carboxylate
CAS 190895-01-3C15H9N2NaO2
6-Fluoro-2-(pyridin-2-yl)quinoline-4-carboxylic acid chemical structure, C15H9FN2O2, CAS 588681-44-1
6-Fluoro-2-(pyridin-2-yl)quinoline-4-carboxylic acid
CAS 588681-44-1C15H9FN2O2
8-Chloro-2-pyridin-2-ylquinoline-4-carboxylic acid chemical structure, C15H9ClN2O2, CAS 52413-50-0
8-Chloro-2-pyridin-2-ylquinoline-4-carboxylic acid
CAS 52413-50-0C15H9ClN2O2
8-Methyl-2-pyridin-2-ylquinoline-4-carboxylic acid chemical structure, C16H12N2O2, CAS 107027-35-0
8-Methyl-2-pyridin-2-ylquinoline-4-carboxylic acid
CAS 107027-35-0C16H12N2O2
6-Chloro-2-pyridin-2-ylquinoline-4-carboxylic acid chemical structure, C15H9ClN2O2, CAS 667412-62-6
6-Chloro-2-pyridin-2-ylquinoline-4-carboxylic acid
CAS 667412-62-6C15H9ClN2O2
7-Chloro-8-methyl-2-pyridin-2-ylquinoline-4-carboxylic acid chemical structure, C16H11ClN2O2, CAS 588696-82-6
7-Chloro-8-methyl-2-pyridin-2-ylquinoline-4-carboxylic acid
CAS 588696-82-6C16H11ClN2O2
6-Isopropyl-2-pyridin-2-ylquinoline-4-carboxylic acid chemical structure, C18H16N2O2, CAS 897561-16-9
6-Isopropyl-2-pyridin-2-ylquinoline-4-carboxylic acid
CAS 897561-16-9C18H16N2O2
N-(Butan-2-yl)-2-(pyridin-2-yl)quinoline-4-carboxamide chemical structure, C19H19N3O, CAS 690217-66-4
N-(Butan-2-yl)-2-(pyridin-2-yl)quinoline-4-carboxamide
CAS 690217-66-4C19H19N3O
N-(3-Methylbutyl)-2-(pyridin-2-yl)quinoline-4-carboxamide chemical structure, C20H21N3O, CAS 690217-72-2
N-(3-Methylbutyl)-2-(pyridin-2-yl)quinoline-4-carboxamide
CAS 690217-72-2C20H21N3O
Methyl 2-(pyridin-2-yl)quinoline-4-carboxylate chemical structure, C16H12N2O2, CAS 5110-05-4
Methyl 2-(pyridin-2-yl)quinoline-4-carboxylate
CAS 5110-05-4C16H12N2O2
7,8-Dimethyl-2-pyridin-2-ylquinoline-4-carboxylic acid chemical structure, C17H14N2O2, CAS 588681-46-3
7,8-Dimethyl-2-pyridin-2-ylquinoline-4-carboxylic acid
CAS 588681-46-3C17H14N2O2