CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 25 atoms

9 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
9
With full pages
0
Scaffold SMILES

O=C(CN1CCN(c2ccccc2)CC1)Nc1c[nH]c2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CN1CCN(c2ccccc2)CC1)Nc1c[nH]c2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

Methyl 1,5-dimethyl-3-[[2-(4-phenylpiperazin-1-yl)acetyl]amino]indole-2-carboxylate chemical structure, C24H28N4O3, CAS 899394-93-5
Methyl 1,5-dimethyl-3-[[2-(4-phenylpiperazin-1-yl)acetyl]amino]indole-2-carboxylate
CAS 899394-93-5C24H28N4O3
Methyl 3-[[2-[4-(2,3-dimethylphenyl)piperazin-1-yl]acetyl]amino]-4-methyl-1H-indole-2-carboxylate chemical structure, C25H30N4O3, CAS 848930-99-4
Methyl 3-[[2-[4-(2,3-dimethylphenyl)piperazin-1-yl]acetyl]amino]-4-methyl-1H-indole-2-carboxylate
CAS 848930-99-4C25H30N4O3
Methyl 3-({[4-(5-chloro-2-methylphenyl)-1-piperazinyl]acetyl}amino)-4-methyl-1H-indole-2-carboxylate chemical structure, C24H27ClN4O3, CAS 849009-38-7
Methyl 3-({[4-(5-chloro-2-methylphenyl)-1-piperazinyl]acetyl}amino)-4-methyl-1H-indole-2-carboxylate
CAS 849009-38-7C24H27ClN4O3
Methyl 3-({[(3R)-4-(4-methoxyphenyl)-3-methylpiperazin-1-yl]acetyl}amino)-5-methyl-1H-indole-2-carboxylate chemical structure, C25H30N4O4, CAS 890092-30-5
Methyl 3-({[(3R)-4-(4-methoxyphenyl)-3-methylpiperazin-1-yl]acetyl}amino)-5-methyl-1H-indole-2-carboxylate
CAS 890092-30-5C25H30N4O4
Methyl 3-({[4-(2-fluorophenyl)piperazin-1-yl]acetyl}amino)-5,6-dimethoxy-1H-indole-2-carboxylate chemical structure, C24H27FN4O5, CAS 890092-48-5
Methyl 3-({[4-(2-fluorophenyl)piperazin-1-yl]acetyl}amino)-5,6-dimethoxy-1H-indole-2-carboxylate
CAS 890092-48-5C24H27FN4O5
Ethyl 3-[[2-[4-(2,4-dimethylphenyl)piperazin-1-yl]acetyl]amino]-5-methoxy-1H-indole-2-carboxylate chemical structure, C26H32N4O4, CAS 847244-24-0
Ethyl 3-[[2-[4-(2,4-dimethylphenyl)piperazin-1-yl]acetyl]amino]-5-methoxy-1H-indole-2-carboxylate
CAS 847244-24-0C26H32N4O4
Ethyl 5-methoxy-3-({2-[4-(2-methoxyphenyl)piperazin-1-yl]propanoyl}amino)-1H-indole-2-carboxylate chemical structure, C26H32N4O5, CAS 890092-11-2
Ethyl 5-methoxy-3-({2-[4-(2-methoxyphenyl)piperazin-1-yl]propanoyl}amino)-1H-indole-2-carboxylate
CAS 890092-11-2C26H32N4O5
Methyl 4-methoxy-3-[2-(4-phenylpiperazin-1-yl)propanoylamino]-1H-indole-2-carboxylate chemical structure, C24H28N4O4, CAS 877787-80-9
Methyl 4-methoxy-3-[2-(4-phenylpiperazin-1-yl)propanoylamino]-1H-indole-2-carboxylate
CAS 877787-80-9C24H28N4O4
AC1Nrdvx chemical structure, C26H32N4O3, CAS 4801-81-4
AC1Nrdvx
CAS 4801-81-4C26H32N4O3