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Murcko scaffold

2-[(4-Oxo-3-phenyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)sulfanyl]-N-phenylacetamide scaffold

223 chemicals on CompoundList share this ring system.

Rings: 5
Scaffold atoms: 31
Chemicals: 223
With full pages: 118

Scaffold SMILES

O=C(CSc1nc2sc3c(c2c(=O)n1-c1ccccc1)CCCC3)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 2-[(4-Oxo-3-phenyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)sulfanyl]-N-phenylacetamide page

Murcko scaffold O=C(CSc1nc2sc3c(c2c(=O)n1-c1ccccc1)CCCC3)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 223 chemicals

N-(3-Methoxyphenyl)-2-{[3-(4-methylphenyl)-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-2-yl]sulfanyl}acetamide chemical structure, C26H25N3O3S2, CAS 499124-29-7

N-(3-Methoxyphenyl)-2-{[3-(4-methylphenyl)-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-2-yl]sulfanyl}acetamide

CAS 499124-29-7C₂₆H₂₅N₃O₃S₂

N-(3,4-Dimethoxyphenyl)-2-{[3-(4-methylphenyl)-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-2-yl]sulfanyl}acetamide chemical structure, C27H27N3O4S2, CAS 499124-31-1

N-(3,4-Dimethoxyphenyl)-2-{[3-(4-methylphenyl)-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-2-yl]sulfanyl}acetamide

CAS 499124-31-1C₂₇H₂₇N₃O₄S₂

2-[[3-(4-Fluorophenyl)-4-oxo-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl]sulfanyl]-N-phenylacetamide chemical structure, C24H20FN3O2S2, CAS 496968-78-6

2-[[3-(4-Fluorophenyl)-4-oxo-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl]sulfanyl]-N-phenylacetamide

CAS 496968-78-6C₂₄H₂₀FN₃O₂S₂

N-(4-Methoxyphenyl)-2-[[3-(4-methylphenyl)-4-oxo-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl]sulfanyl]acetamide chemical structure, C26H25N3O3S2, CAS 332947-19-0

N-(4-Methoxyphenyl)-2-[[3-(4-methylphenyl)-4-oxo-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl]sulfanyl]acetamide

CAS 332947-19-0C₂₆H₂₅N₃O₃S₂

N-(2,4-Dimethoxyphenyl)-2-[[3-(4-methylphenyl)-4-oxo-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl]sulfanyl]acetamide chemical structure, C27H27N3O4S2, CAS 332947-30-5

N-(2,4-Dimethoxyphenyl)-2-[[3-(4-methylphenyl)-4-oxo-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl]sulfanyl]acetamide

CAS 332947-30-5C₂₇H₂₇N₃O₄S₂

N-(4-Fluorophenyl)-2-[(4-oxo-3-phenyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)sulfanyl]acetamide chemical structure, C24H20FN3O2S2, CAS 332869-64-4

N-(4-Fluorophenyl)-2-[(4-oxo-3-phenyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)sulfanyl]acetamide

CAS 332869-64-4C₂₄H₂₀FN₃O₂S₂

2-[(4-Oxo-3-phenyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)sulfanyl]-N-phenylacetamide chemical structure, C24H21N3O2S2, CAS 332412-66-5

2-[(4-Oxo-3-phenyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)sulfanyl]-N-phenylacetamide

CAS 332412-66-5C₂₄H₂₁N₃O₂S₂

N-(4-Acetylphenyl)-2-((4-oxo-3-(p-tolyl)-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamide chemical structure, C27H25N3O3S2, CAS 332947-18-9

N-(4-Acetylphenyl)-2-((4-oxo-3-(p-tolyl)-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamide

CAS 332947-18-9C₂₇H₂₅N₃O₃S₂

$N-(2-Methoxyphenyl)-2-({3-oxo-4-phenyl-8-thia-4,6-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),5-trien-5-yl}sulfanyl)acetamide chemical structure, C25H23N3O3S2, CAS 500112-78-7$

N-(2-Methoxyphenyl)-2-({3-oxo-4-phenyl-8-thia-4,6-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),5-trien-5-yl}sulfanyl)acetamide

CAS 500112-78-7C₂₅H₂₃N₃O₃S₂

N-(2,4-Dimethoxyphenyl)-2-((3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro(1)benzothieno(2,3-D)pyrimidin-2-yl)sulfanyl)acetamide chemical structure, C27H27N3O5S2, CAS 477330-27-1

N-(2,4-Dimethoxyphenyl)-2-((3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro(1)benzothieno(2,3-D)pyrimidin-2-yl)sulfanyl)acetamide

CAS 477330-27-1C₂₇H₂₇N₃O₅S₂

2-{[3-(4-Methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-2-yl]sulfanyl}-N-(4-methylphenyl)acetamide chemical structure, C26H25N3O3S2, CAS 498569-87-2

2-{[3-(4-Methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-2-yl]sulfanyl}-N-(4-methylphenyl)acetamide

CAS 498569-87-2C₂₆H₂₅N₃O₃S₂

2-{[3-(4-Methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-D]pyrimidin-2-yl]sulfanyl}-N-(2-methylphenyl)acetamide chemical structure, C26H25N3O3S2, CAS 476485-66-2

2-{[3-(4-Methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-D]pyrimidin-2-yl]sulfanyl}-N-(2-methylphenyl)acetamide

CAS 476485-66-2C₂₆H₂₅N₃O₃S₂

N-(4-Methoxyphenyl)-2-((3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro(1)benzothieno(2,3-D)pyrimidin-2-yl)sulfanyl)acetamide chemical structure, C26H25N3O4S2, CAS 477329-07-0

N-(4-Methoxyphenyl)-2-((3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro(1)benzothieno(2,3-D)pyrimidin-2-yl)sulfanyl)acetamide

CAS 477329-07-0C₂₆H₂₅N₃O₄S₂

2-{[3-(4-Ethoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-2-yl]sulfanyl}-N-(3-methoxyphenyl)acetamide chemical structure, C27H27N3O4S2, CAS 499125-41-6

2-{[3-(4-Ethoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-2-yl]sulfanyl}-N-(3-methoxyphenyl)acetamide

CAS 499125-41-6C₂₇H₂₇N₃O₄S₂

N-(4-Fluorophenyl)-2-{[3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-D]pyrimidin-2-yl]sulfanyl}acetamide chemical structure, C25H22FN3O3S2, CAS 477329-47-8

N-(4-Fluorophenyl)-2-{[3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-D]pyrimidin-2-yl]sulfanyl}acetamide

CAS 477329-47-8C₂₅H₂₂FN₃O₃S₂

N-(2-Ethoxyphenyl)-2-{[3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-D]pyrimidin-2-yl]sulfanyl}acetamide chemical structure, C27H27N3O4S2, CAS 477331-41-2

N-(2-Ethoxyphenyl)-2-{[3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-D]pyrimidin-2-yl]sulfanyl}acetamide

CAS 477331-41-2C₂₇H₂₇N₃O₄S₂

N-[4-(Acetylamino)phenyl]-2-{[3-(4-methylphenyl)-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-2-yl]sulfanyl}acetamide chemical structure, C27H26N4O3S2, CAS 499124-17-3

N-[4-(Acetylamino)phenyl]-2-{[3-(4-methylphenyl)-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-2-yl]sulfanyl}acetamide

CAS 499124-17-3C₂₇H₂₆N₄O₃S₂

N-(2-Methoxy-5-methylphenyl)-2-{[3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-H exahydro[1]benzothieno[2,3-D]pyrimidin-2-yl]sulfanyl}acetamide chemical structure, C27H27N3O4S2, CAS 477330-54-4

N-(2-Methoxy-5-methylphenyl)-2-{[3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-H exahydro[1]benzothieno[2,3-D]pyrimidin-2-yl]sulfanyl}acetamide

CAS 477330-54-4C₂₇H₂₇N₃O₄S₂

N-(3-Methoxyphenyl)-2-{[3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-D]pyrimidin-2-yl]sulfanyl}acetamide chemical structure, C26H25N3O4S2, CAS 477330-86-2

N-(3-Methoxyphenyl)-2-{[3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-D]pyrimidin-2-yl]sulfanyl}acetamide

CAS 477330-86-2C₂₆H₂₅N₃O₄S₂

N-(2-Fluorophenyl)-2-((3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro(1)benzothieno(2,3-D)pyrimidin-2-yl)sulfanyl)acetamide chemical structure, C25H22FN3O3S2, CAS 477331-63-8

N-(2-Fluorophenyl)-2-((3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro(1)benzothieno(2,3-D)pyrimidin-2-yl)sulfanyl)acetamide

CAS 477331-63-8C₂₅H₂₂FN₃O₃S₂

N-(3-Fluorophenyl)-2-{[3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-D]pyrimidin-2-yl]sulfanyl}acetamide chemical structure, C25H22FN3O3S2, CAS 477331-47-8

N-(3-Fluorophenyl)-2-{[3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-D]pyrimidin-2-yl]sulfanyl}acetamide

CAS 477331-47-8C₂₅H₂₂FN₃O₃S₂

2-{[3-(4-Methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-D]pyrimidin-2-yl]sulfanyl}-N-(3-methylphenyl)acetamide chemical structure, C26H25N3O3S2, CAS 477330-41-9

2-{[3-(4-Methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-D]pyrimidin-2-yl]sulfanyl}-N-(3-methylphenyl)acetamide

CAS 477330-41-9C₂₆H₂₅N₃O₃S₂

N-(4-Ethoxyphenyl)-2-{[3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-D]pyrimidin-2-yl]sulfanyl}acetamide chemical structure, C27H27N3O4S2, CAS 477330-94-2

N-(4-Ethoxyphenyl)-2-{[3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-D]pyrimidin-2-yl]sulfanyl}acetamide

CAS 477330-94-2C₂₇H₂₇N₃O₄S₂

N-(3,5-Dimethoxyphenyl)-2-((3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro(1)benzothieno(2,3-D)pyrimidin-2-yl)sulfanyl)acetamide chemical structure, C27H27N3O5S2, CAS 477329-44-5

N-(3,5-Dimethoxyphenyl)-2-((3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydro(1)benzothieno(2,3-D)pyrimidin-2-yl)sulfanyl)acetamide

CAS 477329-44-5C₂₇H₂₇N₃O₅S₂