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Murcko scaffold

4-(2,4-Diphenyl-1H-imidazol-5-yl)pyridine scaffold

29 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
29
With full pages
7
Scaffold SMILES

c1ccc(-c2nc(-c3ccccc3)c(-c3ccncc3)[nH]2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(2,4-Diphenyl-1H-imidazol-5-yl)pyridine page
Murcko scaffold c1ccc(-c2nc(-c3ccccc3)c(-c3ccncc3)[nH]2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 29 of 29 chemicals

4-(4-(3-Iodophenyl)-2-(4-(methylsulfinyl)phenyl)-1H-imidazol-5-yl)pyridine chemical structure, C21H16IN3OS, CAS 189319-35-5
4-(4-(3-Iodophenyl)-2-(4-(methylsulfinyl)phenyl)-1H-imidazol-5-yl)pyridine
CAS 189319-35-5C21H16IN3OS
PD-169316 chemical structure, C20H13FN4O2, CAS 152121-53-4
PD-169316
CAS 152121-53-4C20H13FN4O2
Sb-202190 chemical structure, C20H14FN3O, CAS 152121-30-7
Sb-202190
CAS 152121-30-7C20H14FN3O
Sb-203580 chemical structure, C21H16FN3OS, CAS 152121-47-6
Sb-203580
CAS 152121-47-6C21H16FN3OS
SB 203580, Sulfone chemical structure, C21H16FN3O2S, CAS 152121-46-5
SB 203580, Sulfone
CAS 152121-46-5C21H16FN3O2S
Adezmapimod, (S)- chemical structure, C21H16FN3OS, CAS 896734-47-7
Adezmapimod, (S)-
CAS 896734-47-7C21H16FN3OS
4-[5-(4-Fluoro-phenyl)-2-phenyl-3H-imidazol-4-yl]-pyridine chemical structure, C20H14FN3, CAS 152121-51-2
4-[5-(4-Fluoro-phenyl)-2-phenyl-3H-imidazol-4-yl]-pyridine
CAS 152121-51-2C20H14FN3
4-[4-(4-Fluorophenyl)-2-[4-(methylthio)phenyl]-1H-imidazol-5-yl]pyridine chemical structure, C21H16FN3S, CAS 152121-44-3
4-[4-(4-Fluorophenyl)-2-[4-(methylthio)phenyl]-1H-imidazol-5-yl]pyridine
CAS 152121-44-3C21H16FN3S
4-[2-(2-Bromophenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]pyridine chemical structure, C20H13BrFN3, CAS 384820-17-1
4-[2-(2-Bromophenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]pyridine
CAS 384820-17-1C20H13BrFN3
2-(4-Aminophenyl)-4-(4-fluorophenyl)-5-(4-pyridyl)-1H-imidazole chemical structure, C20H15FN4, CAS 152121-54-5
2-(4-Aminophenyl)-4-(4-fluorophenyl)-5-(4-pyridyl)-1H-imidazole
CAS 152121-54-5C20H15FN4
2-Chloro-5-(2-phenyl-5-pyridin-4-yl-1H-imidazol-4-yl)phenol chemical structure, C20H14ClN3O, CAS 303727-31-3
2-Chloro-5-(2-phenyl-5-pyridin-4-yl-1H-imidazol-4-yl)phenol
CAS 303727-31-3C20H14ClN3O
4-[2-(4-Bromophenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]pyridine chemical structure, C20H13BrFN3, CAS 208182-31-4
4-[2-(4-Bromophenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]pyridine
CAS 208182-31-4C20H13BrFN3
Methyl 4-[4-(4-fluorophenyl)-5-(4-pyridyl)-1H-imidazol-2-yl]-benzoate chemical structure, C22H16FN3O2, CAS 152121-45-4
Methyl 4-[4-(4-fluorophenyl)-5-(4-pyridyl)-1H-imidazol-2-yl]-benzoate
CAS 152121-45-4C22H16FN3O2
4-[5-(4-Fluoro-phenyl)-2-(4-methoxy-phenyl)-3H-imidazol-4-yl]-pyridine chemical structure, C21H16FN3O, CAS 152121-61-4
4-[5-(4-Fluoro-phenyl)-2-(4-methoxy-phenyl)-3H-imidazol-4-yl]-pyridine
CAS 152121-61-4C21H16FN3O
4-[5-(4-Fluoro-phenyl)-2-p-tolyl-3H-imidazol-4-yl]-pyridine chemical structure, C21H16FN3, CAS 208182-49-4
4-[5-(4-Fluoro-phenyl)-2-p-tolyl-3H-imidazol-4-yl]-pyridine
CAS 208182-49-4C21H16FN3
Pyridine, 4-[2-(4-methoxyphenyl)-1-methyl-4-phenyl-1H-imidazol-5-yl]- chemical structure, C22H19N3O, CAS 152121-21-6
Pyridine, 4-[2-(4-methoxyphenyl)-1-methyl-4-phenyl-1H-imidazol-5-yl]-
CAS 152121-21-6C22H19N3O
2-(4-Aminomethylphenyl)-4-(4-fluorophenyl)-5-(4-pyridyl)-1H-imidazole chemical structure, C21H17FN4, CAS 152121-34-1
2-(4-Aminomethylphenyl)-4-(4-fluorophenyl)-5-(4-pyridyl)-1H-imidazole
CAS 152121-34-1C21H17FN4
4-(2,4-Diphenyl-1H-imidazol-5-yl)pyridine chemical structure, C20H15N3, CAS 208641-25-2
4-(2,4-Diphenyl-1H-imidazol-5-yl)pyridine
CAS 208641-25-2C20H15N3
4-[4-(4-Fluorophenyl)-5-(4-pyridyl)-1H-imidazol-2-yl]benzoic acid chemical structure, C21H14FN3O2, CAS 152121-32-9
4-[4-(4-Fluorophenyl)-5-(4-pyridyl)-1H-imidazol-2-yl]benzoic acid
CAS 152121-32-9C21H14FN3O2
1H-Imidazole-1-ethanol, 2,4-diphenyl-5-(4-pyridinyl)- chemical structure, C22H19N3O, CAS 676168-42-6
1H-Imidazole-1-ethanol, 2,4-diphenyl-5-(4-pyridinyl)-
CAS 676168-42-6C22H19N3O
2-(4-Cyanophenyl)4-(4-fluorophenyl)-5-(4-pyridyl)-1H-imidazole chemical structure, C21H13FN4, CAS 152121-19-2
2-(4-Cyanophenyl)4-(4-fluorophenyl)-5-(4-pyridyl)-1H-imidazole
CAS 152121-19-2C21H13FN4
4-[5-(4-Fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-4-yl]-pyridine monohydrochloride chemical structure, C21H17ClFN3OS, CAS 869185-85-3
4-[5-(4-Fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-4-yl]-pyridine monohydrochloride
CAS 869185-85-3C21H17ClFN3OS
4-[4-(4-Fluorophenyl)-2-[4-[(R)-methylsulfinyl]phenyl]-1H-imidazol-5-yl]pyridine chemical structure, C21H16FN3OS, CAS 652162-77-1
4-[4-(4-Fluorophenyl)-2-[4-[(R)-methylsulfinyl]phenyl]-1H-imidazol-5-yl]pyridine
CAS 652162-77-1C21H16FN3OS
4-[2-(2-Chlorophenyl)-4-(3-methoxyphenyl)-1H-imidazol-5-yl]pyridine chemical structure, C21H16ClN3O, CAS 192822-34-7
4-[2-(2-Chlorophenyl)-4-(3-methoxyphenyl)-1H-imidazol-5-yl]pyridine
CAS 192822-34-7C21H16ClN3O