Murcko scaffold
1,3,5-Triphenylpyrazole scaffold
89 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 23
- Chemicals
- 89
- With full pages
- 5
Scaffold SMILES
c1ccc(-c2cc(-c3ccccc3)n(-c3ccccc3)n2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 89 chemicals
5-(4-Chlorophenyl)-1,3-diphenylpyrazole
CAS 27293-94-3C21H15ClN2
3-(4-Chlorophenyl)-1,5-diphenyl-1H-pyrazole
CAS 27293-95-4C21H15ClN2
3,5-Bis(4-chlorophenyl)-1-phenyl-1H-pyrazole
CAS 27293-96-5C21H14Cl2N2
5-(4-Chlorophenyl)-3-(4-methoxyphenyl)-1-phenyl-1H-pyrazole
CAS 27301-45-7C22H17ClN2O
1,5-Bis(4-chlorophenyl)-3-phenyl-1H-pyrazole
CAS 27293-97-6C21H14Cl2N2
3-(4-Methylphenyl)-1,5-diphenyl-1H-pyrazole
CAS 16112-34-8C22H18N2
1,3,5-Triphenylpyrazole-4-carboxylic acid
CAS 53685-84-0C22H16N2O2
3-(4-Methoxyphenyl)-1,5-diphenyl-1H-pyrazole
CAS 33045-40-8C22H18N2O
1,3,5-Triphenylpyrazole
CAS 2183-27-9C21H16N2
1H-Pyrazole-4-acetic acid, 3-(4-methoxyphenyl)-1,5-diphenyl-
CAS 51431-04-0C24H20N2O3
1-(4-Nitrophenyl)-3,5-diphenylpyrazole
CAS 10252-51-4C21H15N3O2
1,3,5-Triphenylpyrazole-4-carbaldehyde
CAS 68426-71-1C22H16N2O
4-(3,5-Diphenyl-pyrazol-1-yl)-benzoic acid
CAS 71945-09-0C22H16N2O2
![[4-(3,5-Diphenylpyrazol-1-yl)-2,3,5,6-tetrafluorophenyl]methanol chemical structure, C22H14F4N2O, CAS 312314-10-6](/s/UXEYRWRAHDEGMM-UHFFFAOYSA-N.svg)
[4-(3,5-Diphenylpyrazol-1-yl)-2,3,5,6-tetrafluorophenyl]methanol
CAS 312314-10-6C22H14F4N2O
1H-Pyrazole-4-carboxylic acid, 1,3,5-triphenyl-, ethyl ester
CAS 7189-12-0C24H20N2O2
Trifezolac
CAS 32710-91-1C23H18N2O2
1-(4-Bromo-2-isopropylphenyl)-3,5-diphenyl-1H-pyrazole
CAS 618444-08-9C24H21BrN2
4-Methyl-1,3,5-triphenyl-1H-pyrazole
CAS 42165-20-8C22H18N2
1-(p-Bromophenyl)-3,5-diphenylpyrazole
CAS 58954-05-5C21H15BrN2
4-(3,5-Diphenylpyrazolyl)benzaldehyde
CAS 71945-17-0C22H16N2O
![1-(3-Chlorophenyl)-5-phenyl-3-[3-(trifluoromethyl)phenyl]-1H-pyrazole-4-carboxylic acid chemical structure, C23H14ClF3N2O2, CAS 1024480-45-2](/s/FULDERCFEMKTMR-UHFFFAOYSA-N.svg)
1-(3-Chlorophenyl)-5-phenyl-3-[3-(trifluoromethyl)phenyl]-1H-pyrazole-4-carboxylic acid
CAS 1024480-45-2C23H14ClF3N2O2
Propyl pyrazole triol
CAS 263717-53-9C24H22N2O3
1-(2,4-Dimethylphenyl)-3,5-diphenyl-1H-pyrazole
CAS 618442-06-1C23H20N2
![Benzenesulfonamide, 4-[3,5-bis(4-methoxyphenyl)-1H-pyrazol-1-yl]- chemical structure, C23H21N3O4S, CAS 143809-39-6](/s/JSMWYOPCPZTWAA-UHFFFAOYSA-N.svg)
Benzenesulfonamide, 4-[3,5-bis(4-methoxyphenyl)-1H-pyrazol-1-yl]-
CAS 143809-39-6C23H21N3O4S
- Benzenesulfonamide, 4-[5-(4-chlorophenyl)-3-phenyl-1H-pyrazol-1-yl]-78794-60-2C21H16ClN3O2S
- 1H-Pyrazole, 5-(4-bromophenyl)-1,3-diphenyl-16860-56-3C21H15BrN2
- 3 suppliers1-(2-(Di-tert-butylphosphino)phenyl)-3,5-diphenyl-1H-pyrazole628333-86-8C29H33N2P
- 1H-Pyrazole, 5-(3-chlorophenyl)-1,3-diphenyl-16860-57-4C21H15ClN2
- 4-Iodo-1,3,5-triphenyl-1H-pyrazole622374-57-6C21H15IN2
- 3-(4-Methoxyphenyl)-5-(3-methylphenyl)-1-phenyl-1H-pyrazole681293-63-0C23H20N2O
- 4-Chloro-1,3-bis(4-methylphenyl)-5-phenyl-1H-pyrazole88039-33-2C23H19ClN2
- 4-Bromo-1,3-bis(4-methylphenyl)-5-phenyl-1H-pyrazole88039-36-5C23H19BrN2
- 4-[5-(4-Methylphenyl)-3-phenyl-1H-pyrazol-1-yl]benzene-1-sulfonamide111607-61-5C22H19N3O2S
- Methyl 5-(2-methoxyphenyl)-1,3-diphenyl-1H-pyrazole-4-carboxylate119824-79-2C24H20N2O3
- 5-(4-Methylphenyl)-1,3-diphenyl-1H-pyrazole16151-06-7C22H18N2
- 5-(4-Methoxyphenyl)-1,3-diphenyl-1H-pyrazole27301-46-8C22H18N2O
- 1-(2-Chlorophenyl)-4-methyl-3,5-bis(4-methylphenyl)-1H-pyrazole1006324-25-9C24H21ClN2
- 1-(3,4-Dichlorophenyl)-3,5-bis(2,4-dimethoxyphenyl)-1H-pyrazole1006332-57-5C25H22Cl2N2O4
- 1-(3-Chlorophenyl)-3,5-bis(3,4-dimethoxyphenyl)-4-methyl-1H-pyrazole1006318-69-9C26H25ClN2O4
- 3,5-Bis(3,4-dichlorophenyl)-1-phenylpyrazole1006339-38-3C21H12Cl4N2
- 1-(3,5-Dichlorophenyl)-3,5-bis(2,4-dimethoxyphenyl)-1H-pyrazole1006339-58-7C25H22Cl2N2O4
- 4-Chloro-1-(4-chlorophenyl)-3,5-bis(3,4-dichlorophenyl)-1H-pyrazole1006336-86-2C21H10Cl6N2
- 4-Chloro-3,5-bis(3,4-dichlorophenyl)-1-phenyl-1H-pyrazole1006352-68-6C21H11Cl5N2
- 3,5-Bis(3,4-dichlorophenyl)-1-(4-methylphenyl)pyrazole1006340-13-1C22H14Cl4N2
- 3,5-Bis(4-bromophenyl)-1-(2-chlorophenyl)-4-methylpyrazole1006354-45-5C22H15Br2ClN2
- 1,3,5-Tris(4-chlorophenyl)-1H-pyrazole360056-46-8C21H13Cl3N2
- 1-(4-Fluorophenyl)-3,5-bis(4-methoxyphenyl)-1H-pyrazole1006340-54-0C23H19FN2O2
- 1-(3-Chloro-4-methylphenyl)-4-ethyl-3,5-bis(4-methoxyphenyl)-1H-pyrazole1006333-19-2C26H25ClN2O2
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold c1ccc(-c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)cc1](/scaffold/RNIPJYFZGXJSDD-UHFFFAOYSA-N/structure.svg)
c1ccc(-c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)cc125 chemicals
c1ccc(C2=NN(c3ccccc3)C(c3ccccc3)C2)cc123 chemicals
O=C1NC=CC(c2cn(-c3ccccc3)nc2-c2ccccc2)N113 chemicalsn2)cc1](/scaffold/LNOBZXNCABUBKK-UHFFFAOYSA-N/structure.svg)
c1ccc(-c2nn(-c3ccccc3)[n+](-c3ccccc3)n2)cc19 chemicals![Scaffold c1ccc(-c2nc(-c3ccccc3)c(-c3ccncc3)[nH]2)cc1](/scaffold/YYQUGNLGTLHJFO-UHFFFAOYSA-N/structure.svg)
c1ccc(-c2nc(-c3ccccc3)c(-c3ccncc3)[nH]2)cc17 chemicals
C1=CC(c2cn(-c3ccccc3)nc2-c2ccccc2)C=CN13 chemicals
S=C1NC=CC(c2cn(-c3ccccc3)nc2-c2ccccc2)N12 chemicals
c1ccc(-c2nc(-c3ccccc3)c(-c3ccccc3)o2)cc12 chemicals
c1ccc(-c2cn(-c3ccccc3)nc2-c2ccccc2)cc11 chemical![Scaffold c1ccc(-c2nc(N3CCOCC3)s[n+]2-c2ccccc2)cc1](/scaffold/HULZMRLVXSOPQJ-UHFFFAOYSA-N/structure.svg)
c1ccc(-c2nc(N3CCOCC3)s[n+]2-c2ccccc2)cc11 chemical
c1ccc(-c2nc(-c3ccccc3)c(-c3ccccc3)s2)cc11 chemical
O=C1C(c2ccccc2)=C(N2CCOCC2)C(=O)N1c1ccccc11 chemical