CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 25 atoms

7 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
7
With full pages
5
Scaffold SMILES

O=c1c(-c2ccccc2)nc2ccccc2n1OCc1ccccn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c(-c2ccccc2)nc2ccccc2n1OCc1ccccn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

3-(3,4-Dimethoxyphenyl)-1-(2-pyridinylmethoxy)-2(1H)-quinoxalinone 4-oxide chemical structure, C22H19N3O5, CAS 371206-18-7
3-(3,4-Dimethoxyphenyl)-1-(2-pyridinylmethoxy)-2(1H)-quinoxalinone 4-oxide
CAS 371206-18-7C22H19N3O5
3-(4-Bromophenyl)-4-oxido-1-(pyridin-2-ylmethoxy)quinoxalin-4-ium-2-one chemical structure, C20H14BrN3O3, CAS 700854-44-0
3-(4-Bromophenyl)-4-oxido-1-(pyridin-2-ylmethoxy)quinoxalin-4-ium-2-one
CAS 700854-44-0C20H14BrN3O3
3-(4-Chlorophenyl)-4-oxido-1-(pyridin-2-ylmethoxy)quinoxalin-4-ium-2-one chemical structure, C20H14ClN3O3, CAS 371133-09-4
3-(4-Chlorophenyl)-4-oxido-1-(pyridin-2-ylmethoxy)quinoxalin-4-ium-2-one
CAS 371133-09-4C20H14ClN3O3
3-(4-Methylphenyl)-4-oxido-1-(pyridin-2-ylmethoxy)quinoxalin-4-ium-2-one chemical structure, C21H17N3O3, CAS 371924-25-3
3-(4-Methylphenyl)-4-oxido-1-(pyridin-2-ylmethoxy)quinoxalin-4-ium-2-one
CAS 371924-25-3C21H17N3O3
3-(4-Ethoxyphenyl)-4-oxido-1-(pyridin-2-ylmethoxy)quinoxalin-4-ium-2-one chemical structure, C22H19N3O4, CAS 371219-31-7
3-(4-Ethoxyphenyl)-4-oxido-1-(pyridin-2-ylmethoxy)quinoxalin-4-ium-2-one
CAS 371219-31-7C22H19N3O4
3-(4-Fluorophenyl)-4-oxido-1-(pyridin-2-ylmethoxy)quinoxalin-4-ium-2-one chemical structure, C20H14FN3O3, CAS 384367-45-7
3-(4-Fluorophenyl)-4-oxido-1-(pyridin-2-ylmethoxy)quinoxalin-4-ium-2-one
CAS 384367-45-7C20H14FN3O3
3-(3-Nitrophenyl)-4-oxido-1-(pyridin-2-ylmethoxy)quinoxalin-4-ium-2-one chemical structure, C20H14N4O5, CAS 385419-11-4
3-(3-Nitrophenyl)-4-oxido-1-(pyridin-2-ylmethoxy)quinoxalin-4-ium-2-one
CAS 385419-11-4C20H14N4O5