CompoundList
Sign in
Murcko scaffold

N-Phenyl-2-(pyridin-3-yl)quinoline-4-carboxamide scaffold

49 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
49
With full pages
3
Scaffold SMILES

O=C(Nc1ccccc1)c1cc(-c2cccnc2)nc2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-Phenyl-2-(pyridin-3-yl)quinoline-4-carboxamide page
Murcko scaffold O=C(Nc1ccccc1)c1cc(-c2cccnc2)nc2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 49 chemicals

N-[3-Chloro-4-(difluoromethoxy)phenyl]-6,8-dimethyl-2-pyridin-3-ylquinoline-4-carboxamide chemical structure, C24H18ClF2N3O2, CAS 713117-99-8
N-[3-Chloro-4-(difluoromethoxy)phenyl]-6,8-dimethyl-2-pyridin-3-ylquinoline-4-carboxamide
CAS 713117-99-8C24H18ClF2N3O2
N-(4-Fluoro-2-methylphenyl)-6-methyl-2-pyridin-3-ylquinoline-4-carboxamide chemical structure, C23H18FN3O, CAS 713120-06-0
N-(4-Fluoro-2-methylphenyl)-6-methyl-2-pyridin-3-ylquinoline-4-carboxamide
CAS 713120-06-0C23H18FN3O
N-(2-Methoxy-5-nitrophenyl)-6-methyl-2-pyridin-3-ylquinoline-4-carboxamide chemical structure, C23H18N4O4, CAS 713120-20-8
N-(2-Methoxy-5-nitrophenyl)-6-methyl-2-pyridin-3-ylquinoline-4-carboxamide
CAS 713120-20-8C23H18N4O4
6-Chloro-N-(2-methylsulfanylphenyl)-2-pyridin-3-ylquinoline-4-carboxamide chemical structure, C22H16ClN3OS, CAS 727374-39-2
6-Chloro-N-(2-methylsulfanylphenyl)-2-pyridin-3-ylquinoline-4-carboxamide
CAS 727374-39-2C22H16ClN3OS
N-[2-Fluoro-5-(trifluoromethyl)phenyl]-6-methyl-2-pyridin-3-ylquinoline-4-carboxamide chemical structure, C23H15F4N3O, CAS 713120-87-7
N-[2-Fluoro-5-(trifluoromethyl)phenyl]-6-methyl-2-pyridin-3-ylquinoline-4-carboxamide
CAS 713120-87-7C23H15F4N3O
N-[4-(tert-Butylsulfamoyl)phenyl]-6-methyl-2-pyridin-3-ylquinoline-4-carboxamide chemical structure, C26H26N4O3S, CAS 713121-46-1
N-[4-(tert-Butylsulfamoyl)phenyl]-6-methyl-2-pyridin-3-ylquinoline-4-carboxamide
CAS 713121-46-1C26H26N4O3S
N-(4-Bromophenyl)-8-chloro-2-pyridin-3-ylquinoline-4-carboxamide chemical structure, C21H13BrClN3O, CAS 713121-47-2
N-(4-Bromophenyl)-8-chloro-2-pyridin-3-ylquinoline-4-carboxamide
CAS 713121-47-2C21H13BrClN3O
6-Bromo-N-(3,5-dimethoxyphenyl)-2-pyridin-3-ylquinoline-4-carboxamide chemical structure, C23H18BrN3O3, CAS 713489-79-3
6-Bromo-N-(3,5-dimethoxyphenyl)-2-pyridin-3-ylquinoline-4-carboxamide
CAS 713489-79-3C23H18BrN3O3
N-(3-Ethylphenyl)-7,8-dimethyl-2-pyridin-3-ylquinoline-4-carboxamide chemical structure, C25H23N3O, CAS 713114-47-7
N-(3-Ethylphenyl)-7,8-dimethyl-2-pyridin-3-ylquinoline-4-carboxamide
CAS 713114-47-7C25H23N3O
6-Bromo-N-[2-(difluoromethoxy)-4-methylphenyl]-2-pyridin-3-ylquinoline-4-carboxamide chemical structure, C23H16BrF2N3O2, CAS 713114-99-9
6-Bromo-N-[2-(difluoromethoxy)-4-methylphenyl]-2-pyridin-3-ylquinoline-4-carboxamide
CAS 713114-99-9C23H16BrF2N3O2
6-Chloro-N-[2-(difluoromethoxy)-4-methylphenyl]-2-pyridin-3-ylquinoline-4-carboxamide chemical structure, C23H16ClF2N3O2, CAS 777869-90-6
6-Chloro-N-[2-(difluoromethoxy)-4-methylphenyl]-2-pyridin-3-ylquinoline-4-carboxamide
CAS 777869-90-6C23H16ClF2N3O2
6-Chloro-N-(2-methyl-3-nitrophenyl)-2-pyridin-3-ylquinoline-4-carboxamide chemical structure, C22H15ClN4O3, CAS 777870-14-1
6-Chloro-N-(2-methyl-3-nitrophenyl)-2-pyridin-3-ylquinoline-4-carboxamide
CAS 777870-14-1C22H15ClN4O3
6-Methyl-N-(2-nitrophenyl)-2-pyridin-3-ylquinoline-4-carboxamide chemical structure, C22H16N4O3, CAS 713119-79-0
6-Methyl-N-(2-nitrophenyl)-2-pyridin-3-ylquinoline-4-carboxamide
CAS 713119-79-0C22H16N4O3
N-Phenyl-2-(pyridin-3-yl)quinoline-4-carboxamide chemical structure, C21H15N3O, CAS 940749-44-0
N-Phenyl-2-(pyridin-3-yl)quinoline-4-carboxamide
CAS 940749-44-0C21H15N3O
N-(4-Bromophenyl)-6-methyl-2-(pyridin-3-yl)quinoline-4-carboxamide chemical structure, C22H16BrN3O, CAS 667440-64-4
N-(4-Bromophenyl)-6-methyl-2-(pyridin-3-yl)quinoline-4-carboxamide
CAS 667440-64-4C22H16BrN3O
N-(3-Chloro-4-fluorophenyl)-2-(pyridin-3-yl)quinoline-4-carboxamide chemical structure, C21H13ClFN3O, CAS 931366-76-6
N-(3-Chloro-4-fluorophenyl)-2-(pyridin-3-yl)quinoline-4-carboxamide
CAS 931366-76-6C21H13ClFN3O
N-(4-Methylphenyl)-2-(pyridin-3-yl)quinoline-4-carboxamide chemical structure, C22H17N3O, CAS 954772-55-5
N-(4-Methylphenyl)-2-(pyridin-3-yl)quinoline-4-carboxamide
CAS 954772-55-5C22H17N3O
N-(4-Methoxyphenyl)-2-(pyridin-3-yl)quinoline-4-carboxamide chemical structure, C22H17N3O2, CAS 954358-63-5
N-(4-Methoxyphenyl)-2-(pyridin-3-yl)quinoline-4-carboxamide
CAS 954358-63-5C22H17N3O2
N-(3-Methoxyphenyl)-2-(pyridin-3-yl)quinoline-4-carboxamide chemical structure, C22H17N3O2, CAS 954772-58-8
N-(3-Methoxyphenyl)-2-(pyridin-3-yl)quinoline-4-carboxamide
CAS 954772-58-8C22H17N3O2
N-(2,5-Dichlorophenyl)-2-(pyridin-3-yl)quinoline-4-carboxamide chemical structure, C21H13Cl2N3O, CAS 954828-02-5
N-(2,5-Dichlorophenyl)-2-(pyridin-3-yl)quinoline-4-carboxamide
CAS 954828-02-5C21H13Cl2N3O
N-(2,4-Dichlorophenyl)-2-(pyridin-3-yl)quinoline-4-carboxamide chemical structure, C21H13Cl2N3O, CAS 954305-02-3
N-(2,4-Dichlorophenyl)-2-(pyridin-3-yl)quinoline-4-carboxamide
CAS 954305-02-3C21H13Cl2N3O
N-(4-Chlorophenyl)-2-(pyridin-3-yl)quinoline-4-carboxamide chemical structure, C21H14ClN3O, CAS 954358-71-5
N-(4-Chlorophenyl)-2-(pyridin-3-yl)quinoline-4-carboxamide
CAS 954358-71-5C21H14ClN3O
N-(3-Chlorophenyl)-2-(pyridin-3-yl)quinoline-4-carboxamide chemical structure, C21H14ClN3O, CAS 954772-64-6
N-(3-Chlorophenyl)-2-(pyridin-3-yl)quinoline-4-carboxamide
CAS 954772-64-6C21H14ClN3O
N-(2-Chlorophenyl)-2-(pyridin-3-yl)quinoline-4-carboxamide chemical structure, C21H14ClN3O, CAS 954828-05-8
N-(2-Chlorophenyl)-2-(pyridin-3-yl)quinoline-4-carboxamide
CAS 954828-05-8C21H14ClN3O