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Murcko scaffold

4-(1H-Imidazol-5-yl)thiazole scaffold

39 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
39
With full pages
1
Scaffold SMILES

c1ncc(-c2cscn2)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(1H-Imidazol-5-yl)thiazole page
Murcko scaffold c1ncc(-c2cscn2)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 39 of 39 chemicals

Zaltidine chemical structure, C8H10N6S, CAS 85604-00-8
Zaltidine
CAS 85604-00-8C8H10N6S
CP-66,948 chemical structure, C13H20N6S, CAS 101189-47-3
CP-66,948
CAS 101189-47-3C13H20N6S
N''-{4-[2-(Methylamino)-1H-imidazol-5-yl]-1,3-thiazol-2-yl}guanidine chemical structure, C8H11N7S, CAS 82982-67-0
N''-{4-[2-(Methylamino)-1H-imidazol-5-yl]-1,3-thiazol-2-yl}guanidine
CAS 82982-67-0C8H11N7S
N''-{4-[2-(Ethylamino)-1H-imidazol-5-yl]-1,3-thiazol-2-yl}guanidine chemical structure, C9H13N7S, CAS 88723-92-6
N''-{4-[2-(Ethylamino)-1H-imidazol-5-yl]-1,3-thiazol-2-yl}guanidine
CAS 88723-92-6C9H13N7S
N''-{4-[2-(Propylamino)-1H-imidazol-5-yl]-1,3-thiazol-2-yl}guanidine chemical structure, C10H15N7S, CAS 88723-93-7
N''-{4-[2-(Propylamino)-1H-imidazol-5-yl]-1,3-thiazol-2-yl}guanidine
CAS 88723-93-7C10H15N7S
N''-(4-{2-[(Propan-2-yl)amino]-1H-imidazol-5-yl}-1,3-thiazol-2-yl)guanidine chemical structure, C10H15N7S, CAS 88723-74-4
N''-(4-{2-[(Propan-2-yl)amino]-1H-imidazol-5-yl}-1,3-thiazol-2-yl)guanidine
CAS 88723-74-4C10H15N7S
N''-{4-[2-(Butylamino)-1H-imidazol-5-yl]-1,3-thiazol-2-yl}guanidine chemical structure, C11H17N7S, CAS 88723-94-8
N''-{4-[2-(Butylamino)-1H-imidazol-5-yl]-1,3-thiazol-2-yl}guanidine
CAS 88723-94-8C11H17N7S
Guanidine, N-heptyl-Na(2)-[4-(2-methyl-1H-imidazol-4-yl)-2-thiazolyl]- chemical structure, C15H24N6S, CAS 101189-60-0
Guanidine, N-heptyl-Na(2)-[4-(2-methyl-1H-imidazol-4-yl)-2-thiazolyl]-
CAS 101189-60-0C15H24N6S
Guanidine, N-(4-(2-methyl-1H-imidazol-4-yl)-2-thiazolyl)-N'-pentyl-, dihydrochloride chemical structure, C13H22Cl2N6S, CAS 103140-97-2
Guanidine, N-(4-(2-methyl-1H-imidazol-4-yl)-2-thiazolyl)-N'-pentyl-, dihydrochloride
CAS 103140-97-2C13H22Cl2N6S
Zaltidine hydrochloride chemical structure, C8H12Cl2N6S, CAS 90274-23-0
Zaltidine hydrochloride
CAS 90274-23-0C8H12Cl2N6S
Guanidine, (4-(2-(hexylamino)-1H-imidazol-4-yl)-2-thiazolyl)- chemical structure, C13H21N7S, CAS 88723-96-0
Guanidine, (4-(2-(hexylamino)-1H-imidazol-4-yl)-2-thiazolyl)-
CAS 88723-96-0C13H21N7S
N''-{4-[2-(Octylamino)-1H-imidazol-5-yl]-1,3-thiazol-2-yl}guanidine chemical structure, C15H25N7S, CAS 88723-71-1
N''-{4-[2-(Octylamino)-1H-imidazol-5-yl]-1,3-thiazol-2-yl}guanidine
CAS 88723-71-1C15H25N7S
N''-{4-[2-(Decylamino)-1H-imidazol-5-yl]-1,3-thiazol-2-yl}guanidine chemical structure, C17H29N7S, CAS 88723-73-3
N''-{4-[2-(Decylamino)-1H-imidazol-5-yl]-1,3-thiazol-2-yl}guanidine
CAS 88723-73-3C17H29N7S
N''-(4-{2-[(Butan-2-yl)amino]-1H-imidazol-5-yl}-1,3-thiazol-2-yl)guanidine chemical structure, C11H17N7S, CAS 88723-75-5
N''-(4-{2-[(Butan-2-yl)amino]-1H-imidazol-5-yl}-1,3-thiazol-2-yl)guanidine
CAS 88723-75-5C11H17N7S
N''-{4-[2-(Pentylamino)-1H-imidazol-5-yl]-1,3-thiazol-2-yl}guanidine chemical structure, C12H19N7S, CAS 88723-95-9
N''-{4-[2-(Pentylamino)-1H-imidazol-5-yl]-1,3-thiazol-2-yl}guanidine
CAS 88723-95-9C12H19N7S
N''-{4-[2-(Heptylamino)-1H-imidazol-5-yl]-1,3-thiazol-2-yl}guanidine chemical structure, C14H23N7S, CAS 88723-97-1
N''-{4-[2-(Heptylamino)-1H-imidazol-5-yl]-1,3-thiazol-2-yl}guanidine
CAS 88723-97-1C14H23N7S
N''-{4-[2-(Nonylamino)-1H-imidazol-5-yl]-1,3-thiazol-2-yl}guanidine chemical structure, C16H27N7S, CAS 88723-98-2
N''-{4-[2-(Nonylamino)-1H-imidazol-5-yl]-1,3-thiazol-2-yl}guanidine
CAS 88723-98-2C16H27N7S
N''-(4-{2-[(3-Methylbutyl)amino]-1H-imidazol-5-yl}-1,3-thiazol-2-yl)guanidine chemical structure, C12H19N7S, CAS 88723-99-3
N''-(4-{2-[(3-Methylbutyl)amino]-1H-imidazol-5-yl}-1,3-thiazol-2-yl)guanidine
CAS 88723-99-3C12H19N7S
N''-{4-[2-(Dimethylamino)-1H-imidazol-5-yl]-1,3-thiazol-2-yl}guanidine chemical structure, C9H13N7S, CAS 88724-06-5
N''-{4-[2-(Dimethylamino)-1H-imidazol-5-yl]-1,3-thiazol-2-yl}guanidine
CAS 88724-06-5C9H13N7S
N''-(4-{2-[Ethyl(methyl)amino]-1H-imidazol-5-yl}-1,3-thiazol-2-yl)guanidine chemical structure, C10H15N7S, CAS 88724-07-6
N''-(4-{2-[Ethyl(methyl)amino]-1H-imidazol-5-yl}-1,3-thiazol-2-yl)guanidine
CAS 88724-07-6C10H15N7S
N''-{4-[2-(Diethylamino)-1H-imidazol-5-yl]-1,3-thiazol-2-yl}guanidine chemical structure, C11H17N7S, CAS 88724-08-7
N''-{4-[2-(Diethylamino)-1H-imidazol-5-yl]-1,3-thiazol-2-yl}guanidine
CAS 88724-08-7C11H17N7S
4-(1H-Imidazol-5-yl)thiazole chemical structure, C6H5N3S, CAS 758724-68-4
4-(1H-Imidazol-5-yl)thiazole
CAS 758724-68-4C6H5N3S
4-(4-Methyl-1H-imidazol-5-yl)-1,3-thiazol-2-amine chemical structure, C7H8N4S, CAS 758718-69-3
4-(4-Methyl-1H-imidazol-5-yl)-1,3-thiazol-2-amine
CAS 758718-69-3C7H8N4S
4-(1-Methyl-1H-imidazol-5-yl)-1,3-thiazol-2-amine chemical structure, C7H8N4S, CAS 1554518-35-2
4-(1-Methyl-1H-imidazol-5-yl)-1,3-thiazol-2-amine
CAS 1554518-35-2C7H8N4S