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Murcko scaffold

Ring system with 3 rings and 21 atoms

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
9
With full pages
3
Scaffold SMILES

c1ccc(COCCCN2CCc3ccccc3C2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(COCCCN2CCc3ccccc3C2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

1-((4-Chlorobenzyl)oxy)-3-(3,4-dihydroisoquinolin-2(1H)-yl)propan-2-ol hydrochloride chemical structure, C19H23Cl2NO2, CAS 473267-36-6
1-((4-Chlorobenzyl)oxy)-3-(3,4-dihydroisoquinolin-2(1H)-yl)propan-2-ol hydrochloride
CAS 473267-36-6C19H23Cl2NO2
1-[(4-Chlorophenyl)methoxy]-3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propan-2-ol chemical structure, C19H22ClNO2, CAS 380192-76-7
1-[(4-Chlorophenyl)methoxy]-3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propan-2-ol
CAS 380192-76-7C19H22ClNO2
1-(Benzyloxy)-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-propanol hydrochloride chemical structure, C19H24ClNO2, CAS 473268-42-7
1-(Benzyloxy)-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-propanol hydrochloride
CAS 473268-42-7C19H24ClNO2
1-(Benzyloxy)-3-(3,4-dihydroisoquinolin-2(1H)-yl)propan-2-ol chemical structure, C19H23NO2, CAS 325820-88-0
1-(Benzyloxy)-3-(3,4-dihydroisoquinolin-2(1H)-yl)propan-2-ol
CAS 325820-88-0C19H23NO2
1-(3,4-Dihydroisoquinolin-2(1H)-yl)-3-((2,5-dimethoxybenzyl)oxy)propan-2-ol hydrochloride chemical structure, C21H28ClNO4, CAS 1185548-93-9
1-(3,4-Dihydroisoquinolin-2(1H)-yl)-3-((2,5-dimethoxybenzyl)oxy)propan-2-ol hydrochloride
CAS 1185548-93-9C21H28ClNO4
1-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-3-((2,5-dimethoxybenzyl)oxy)propan-2-ol hydrochloride chemical structure, C23H32ClNO6, CAS 1217055-16-7
1-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-3-((2,5-dimethoxybenzyl)oxy)propan-2-ol hydrochloride
CAS 1217055-16-7C23H32ClNO6
1-((2,4-Dichlorobenzyl)oxy)-3-(3,4-dihydroisoquinolin-2(1H)-yl)propan-2-ol chemical structure, C19H21Cl2NO2, CAS 1616098-52-2
1-((2,4-Dichlorobenzyl)oxy)-3-(3,4-dihydroisoquinolin-2(1H)-yl)propan-2-ol
CAS 1616098-52-2C19H21Cl2NO2
1-((2,6-Dichlorobenzyl)oxy)-3-(3,4-dihydroisoquinolin-2(1H)-yl)propan-2-ol chemical structure, C19H21Cl2NO2, CAS 1616098-51-1
1-((2,6-Dichlorobenzyl)oxy)-3-(3,4-dihydroisoquinolin-2(1H)-yl)propan-2-ol
CAS 1616098-51-1C19H21Cl2NO2
1-(3,4-Dihydroisoquinolin-2(1H)-yl)-3-((3-methoxybenzyl)oxy)propan-2-ol chemical structure, C20H25NO3, CAS 1616098-58-8
1-(3,4-Dihydroisoquinolin-2(1H)-yl)-3-((3-methoxybenzyl)oxy)propan-2-ol
CAS 1616098-58-8C20H25NO3