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Murcko scaffold

Thiouracil scaffold

261 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
8
Chemicals
261
With full pages
43
Scaffold SMILES

O=c1cc[nH]c(=S)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Thiouracil page
Murcko scaffold O=c1cc[nH]c(=S)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 261 chemicals

1H,3H-Pyrimidine-4-one-2-thione, 1,3-dimethyl- chemical structure, C6H8N2OS, CAS 1194-71-4
1H,3H-Pyrimidine-4-one-2-thione, 1,3-dimethyl-
CAS 1194-71-4C6H8N2OS
6-Amino-1,3-diethyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one chemical structure, C8H13N3OS, CAS 3120-51-2
6-Amino-1,3-diethyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
CAS 3120-51-2C8H13N3OS
6-Amino-1,3-dimethyl-5-nitroso-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone chemical structure, C6H8N4O2S, CAS 6501-95-7
6-Amino-1,3-dimethyl-5-nitroso-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone
CAS 6501-95-7C6H8N4O2S
RefChem:357218 chemical structure, C6H9N3OS, CAS 3120-52-3
RefChem:357218
CAS 3120-52-3C6H9N3OS
5,6-Diamino-1,3-dimethyl-2-sulfanylidene-2,3-dihydropyrimidin-4(1H)-one chemical structure, C6H10N4OS, CAS 6501-96-8
5,6-Diamino-1,3-dimethyl-2-sulfanylidene-2,3-dihydropyrimidin-4(1H)-one
CAS 6501-96-8C6H10N4OS
Propylthiouracil chemical structure, C7H10N2OS, CAS 51-52-5
Propylthiouracil
CAS 51-52-5C7H10N2OS
Methylthiouracil chemical structure, C5H6N2OS, CAS 56-04-2
Methylthiouracil
CAS 56-04-2C5H6N2OS
(2-Mercapto-4-methyl-6-oxo-1,6-dihydropyrimidin-5-yl)acetic acid chemical structure, C7H8N2O3S, CAS 62214-19-1
(2-Mercapto-4-methyl-6-oxo-1,6-dihydropyrimidin-5-yl)acetic acid
CAS 62214-19-1C7H8N2O3S
3-(2-Mercapto-4-methyl-6-oxo-1,6-dihydropyrimidin-5-yl)propanoic acid chemical structure, C8H10N2O3S, CAS 945-12-0
3-(2-Mercapto-4-methyl-6-oxo-1,6-dihydropyrimidin-5-yl)propanoic acid
CAS 945-12-0C8H10N2O3S
Uracil, 5-allyl-6-methyl-2-thio- chemical structure, C8H10N2OS, CAS 102613-14-9
Uracil, 5-allyl-6-methyl-2-thio-
CAS 102613-14-9C8H10N2OS
6-(Methoxymethyl)-2-sulfanylidene-2,3-dihydropyrimidin-4(1H)-one chemical structure, C6H8N2O2S, CAS 175205-07-9
6-(Methoxymethyl)-2-sulfanylidene-2,3-dihydropyrimidin-4(1H)-one
CAS 175205-07-9C6H8N2O2S
5-Isopentyl-2-mercapto-6-methylpyrimidin-4-ol chemical structure, C10H16N2OS, CAS 17005-48-0
5-Isopentyl-2-mercapto-6-methylpyrimidin-4-ol
CAS 17005-48-0C10H16N2OS
2-Thiothymine chemical structure, C5H6N2OS, CAS 636-26-0
2-Thiothymine
CAS 636-26-0C5H6N2OS
Ethyl 1,2,3,4-tetrahydro-4-oxo-2-thioxo-5-pyrimidinecarboxylate chemical structure, C7H8N2O3S, CAS 38026-46-9
Ethyl 1,2,3,4-tetrahydro-4-oxo-2-thioxo-5-pyrimidinecarboxylate
CAS 38026-46-9C7H8N2O3S
6-tert-Butyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one chemical structure, C8H12N2OS, CAS 66698-66-6
6-tert-Butyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
CAS 66698-66-6C8H12N2OS
5-Isopropyl-6-methyl-2-thiouracil chemical structure, C8H12N2OS, CAS 72306-27-5
5-Isopropyl-6-methyl-2-thiouracil
CAS 72306-27-5C8H12N2OS
6-Amino-1-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one chemical structure, C5H7N3OS, CAS 16837-08-4
6-Amino-1-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
CAS 16837-08-4C5H7N3OS
6-Amino-2,3-dihydro-1-propyl-2-thioxo-4(1H)-pyrimidinone chemical structure, C7H11N3OS, CAS 16837-09-5
6-Amino-2,3-dihydro-1-propyl-2-thioxo-4(1H)-pyrimidinone
CAS 16837-09-5C7H11N3OS
3-Amino-6-methyl-2-thioxo-2,3-dihyd chemical structure, C5H7N3OS, CAS 35523-72-9
3-Amino-6-methyl-2-thioxo-2,3-dihyd
CAS 35523-72-9C5H7N3OS
4-Hydroxy-2-sulfanylpyrimidine-5-carbonitrile chemical structure, C5H3N3OS, CAS 23945-49-5
4-Hydroxy-2-sulfanylpyrimidine-5-carbonitrile
CAS 23945-49-5C5H3N3OS
5-Acetyl-6-hydroxy-1,3-dimethyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one chemical structure, C8H10N2O3S, CAS 34925-00-3
5-Acetyl-6-hydroxy-1,3-dimethyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
CAS 34925-00-3C8H10N2O3S
1-(2-Hydroxyethyl)-6-methyl-2-sulfanylidenepyrimidin-4-one chemical structure, C7H10N2O2S, CAS 61736-35-4
1-(2-Hydroxyethyl)-6-methyl-2-sulfanylidenepyrimidin-4-one
CAS 61736-35-4C7H10N2O2S
Ethyl 3-(4-hydroxy-6-methyl-2-sulfanylpyrimidin-5-yl)propanoate chemical structure, C10H14N2O3S, CAS 18149-74-1
Ethyl 3-(4-hydroxy-6-methyl-2-sulfanylpyrimidin-5-yl)propanoate
CAS 18149-74-1C10H14N2O3S
AC1Lipiu chemical structure, C8H10N2OS, CAS 60478-14-0
AC1Lipiu
CAS 60478-14-0C8H10N2OS