CompoundList
Sign in
Murcko scaffold

1-(Phenylacetyl)piperazine scaffold

199 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
199
With full pages
19
Scaffold SMILES

O=C(Cc1ccccc1)N1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(Phenylacetyl)piperazine page
Murcko scaffold O=C(Cc1ccccc1)N1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 199 chemicals

2-Hydroxy-1-(4-methylpiperazin-1-yl)-2-phenylethan-1-one chemical structure, C13H18N2O2, CAS 908829-84-5
2-Hydroxy-1-(4-methylpiperazin-1-yl)-2-phenylethan-1-one
CAS 908829-84-5C13H18N2O2
Piperazine, 1-[5-fluoropentyl]-4-[(3,4-dichlorophenyl)acetyl]- chemical structure, C17H23Cl2FN2O, CAS 141044-94-2
Piperazine, 1-[5-fluoropentyl]-4-[(3,4-dichlorophenyl)acetyl]-
CAS 141044-94-2C17H23Cl2FN2O
1-[(4-Methoxyphenyl)acetyl]-4-methylpiperazine chemical structure, C14H20N2O2, CAS 82966-20-9
1-[(4-Methoxyphenyl)acetyl]-4-methylpiperazine
CAS 82966-20-9C14H20N2O2
2-(2-Methoxyphenyl)-1-(4-methylpiperazin-1-yl)ethanone chemical structure, C14H20N2O2, CAS 348613-47-8
2-(2-Methoxyphenyl)-1-(4-methylpiperazin-1-yl)ethanone
CAS 348613-47-8C14H20N2O2
1-(4-Methylsulfonylpiperazin-1-yl)-2-phenylethanone chemical structure, C13H18N2O3S, CAS 5939-62-8
1-(4-Methylsulfonylpiperazin-1-yl)-2-phenylethanone
CAS 5939-62-8C13H18N2O3S
1-Isopropyl-4-(phenylacetyl)piperazine chemical structure, C15H22N2O, CAS 423738-72-1
1-Isopropyl-4-(phenylacetyl)piperazine
CAS 423738-72-1C15H22N2O
Ethyl 4-[2-(4-chlorophenyl)acetyl]piperazine-1-carboxylate chemical structure, C15H19ClN2O3, CAS 356079-80-6
Ethyl 4-[2-(4-chlorophenyl)acetyl]piperazine-1-carboxylate
CAS 356079-80-6C15H19ClN2O3
1-[(4-Chlorophenyl)acetyl]-4-methylpiperazine chemical structure, C13H17ClN2O, CAS 346727-28-4
1-[(4-Chlorophenyl)acetyl]-4-methylpiperazine
CAS 346727-28-4C13H17ClN2O
1-(4-Pentan-3-ylpiperazin-1-yl)-2-phenylethanone chemical structure, C17H26N2O, CAS 461400-69-1
1-(4-Pentan-3-ylpiperazin-1-yl)-2-phenylethanone
CAS 461400-69-1C17H26N2O
1-(4-Methylpiperazin-1-yl)-2-phenylethanone chemical structure, C13H18N2O, CAS 56230-65-0
1-(4-Methylpiperazin-1-yl)-2-phenylethanone
CAS 56230-65-0C13H18N2O
2-(3,4-Dimethoxyphenyl)-1-(4-methylpiperazin-1-yl)ethanone chemical structure, C15H22N2O3, CAS 219901-25-4
2-(3,4-Dimethoxyphenyl)-1-(4-methylpiperazin-1-yl)ethanone
CAS 219901-25-4C15H22N2O3
4-[(4-Nitrophenyl)acetyl]piperazine-1-carbaldehyde chemical structure, C13H15N3O4, CAS 6428-40-6
4-[(4-Nitrophenyl)acetyl]piperazine-1-carbaldehyde
CAS 6428-40-6C13H15N3O4
1-Bromo-4-(4-methylpiperazinocarbonylmethyl)benzene chemical structure, C13H17BrN2O, CAS 349430-56-4
1-Bromo-4-(4-methylpiperazinocarbonylmethyl)benzene
CAS 349430-56-4C13H17BrN2O
Ethyl 4-[(4-methylphenyl)acetyl]piperazine-1-carboxylate chemical structure, C16H22N2O3, CAS 694446-04-3
Ethyl 4-[(4-methylphenyl)acetyl]piperazine-1-carboxylate
CAS 694446-04-3C16H22N2O3
2-Phenyl-1-(4-propylsulfonylpiperazin-1-yl)ethanone chemical structure, C15H22N2O3S, CAS 428843-21-4
2-Phenyl-1-(4-propylsulfonylpiperazin-1-yl)ethanone
CAS 428843-21-4C15H22N2O3S
Ethanone, 2-(4-fluorophenyl)-1-(4-methyl-1-piperazinyl)- chemical structure, C13H17FN2O, CAS 521300-20-9
Ethanone, 2-(4-fluorophenyl)-1-(4-methyl-1-piperazinyl)-
CAS 521300-20-9C13H17FN2O
2-(2-Chloro-6-fluorophenyl)-1-(4-methylpiperazin-1-yl)ethanone chemical structure, C13H16ClFN2O, CAS 710988-51-5
2-(2-Chloro-6-fluorophenyl)-1-(4-methylpiperazin-1-yl)ethanone
CAS 710988-51-5C13H16ClFN2O
2-(2-Chlorophenyl)-1-(4-methylpiperazin-1-yl)ethanone chemical structure, C13H17ClN2O, CAS 777876-65-0
2-(2-Chlorophenyl)-1-(4-methylpiperazin-1-yl)ethanone
CAS 777876-65-0C13H17ClN2O
1-(Phenylacetyl)piperazine chemical structure, C12H16N2O, CAS 88372-33-2
1-(Phenylacetyl)piperazine
CAS 88372-33-2C12H16N2O
1-(4-Ethylsulfonylpiperazin-1-yl)-2-phenylethanone chemical structure, C14H20N2O3S, CAS 429620-40-6
1-(4-Ethylsulfonylpiperazin-1-yl)-2-phenylethanone
CAS 429620-40-6C14H20N2O3S
Ethyl 4-(2-phenylbutanoyl)piperazine-1-carboxylate chemical structure, C17H24N2O3, CAS 434302-99-5
Ethyl 4-(2-phenylbutanoyl)piperazine-1-carboxylate
CAS 434302-99-5C17H24N2O3
1-[(4-Bromophenyl)acetyl]-4-(methylsulfonyl)piperazine chemical structure, C13H17BrN2O3S, CAS 895935-86-1
1-[(4-Bromophenyl)acetyl]-4-(methylsulfonyl)piperazine
CAS 895935-86-1C13H17BrN2O3S
Piperazine, 1-methyl-4-(2-(4-((1-methylethyl)thio)phenyl)-1-oxopropyl)-, hydrochloride chemical structure, C17H27ClN2OS, CAS 129603-00-5
Piperazine, 1-methyl-4-(2-(4-((1-methylethyl)thio)phenyl)-1-oxopropyl)-, hydrochloride
CAS 129603-00-5C17H27ClN2OS
1-[4-(2-Hydroxyethyl)piperazin-1-yl]-2-phenylethan-1-one chemical structure, C14H20N2O2, CAS 349089-68-5
1-[4-(2-Hydroxyethyl)piperazin-1-yl]-2-phenylethan-1-one
CAS 349089-68-5C14H20N2O2