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Murcko scaffold

Isothiazole scaffold

1,868 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
5
Chemicals
1,868
With full pages
279
Scaffold SMILES

c1cnsc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the Isothiazole page
Murcko scaffold c1cnsc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 97 to 144 of 1,868 chemicals

N~2~,N~2~-Dimethyl-N-(3-methyl-1,2-thiazol-5-yl)alaninamide chemical structure, C9H15N3OS, CAS 90768-63-1
N~2~,N~2~-Dimethyl-N-(3-methyl-1,2-thiazol-5-yl)alaninamide
CAS 90768-63-1C9H15N3OS
Propionamide, 2-(diethylamino)-N-(3-methyl-5-isothiazolyl)- chemical structure, C11H19N3OS, CAS 91334-60-0
Propionamide, 2-(diethylamino)-N-(3-methyl-5-isothiazolyl)-
CAS 91334-60-0C11H19N3OS
4-Isothiazolecarbonitrile, 5-((cyanomethyl)thio)-3-(methylthio)- chemical structure, C7H5N3S3, CAS 72436-95-4
4-Isothiazolecarbonitrile, 5-((cyanomethyl)thio)-3-(methylthio)-
CAS 72436-95-4C7H5N3S3
Acetamide, 2-((4-cyano-3-(methylthio)-5-isothiazolyl)thio)- chemical structure, C7H7N3OS3, CAS 77726-54-6
Acetamide, 2-((4-cyano-3-(methylthio)-5-isothiazolyl)thio)-
CAS 77726-54-6C7H7N3OS3
4-Isothiazolecarbonitrile, 3-((cyanomethyl)thio)-5-(propylthio)- chemical structure, C9H9N3S3, CAS 135489-11-1
4-Isothiazolecarbonitrile, 3-((cyanomethyl)thio)-5-(propylthio)-
CAS 135489-11-1C9H9N3S3
Acetamide, 2-((4-cyano-5-(propylthio)-3-isothiazolyl)thio)- chemical structure, C9H11N3OS3, CAS 135489-13-3
Acetamide, 2-((4-cyano-5-(propylthio)-3-isothiazolyl)thio)-
CAS 135489-13-3C9H11N3OS3
Acetamide, 2-((4-cyano-3-(propylthio)-5-isothiazolyl)thio)- chemical structure, C9H11N3OS3, CAS 135489-21-3
Acetamide, 2-((4-cyano-3-(propylthio)-5-isothiazolyl)thio)-
CAS 135489-21-3C9H11N3OS3
4-Isothiazolecarbonitrile, 5-((cyanomethyl)thio)-3-(propylthio)- chemical structure, C9H9N3S3, CAS 135518-36-4
4-Isothiazolecarbonitrile, 5-((cyanomethyl)thio)-3-(propylthio)-
CAS 135518-36-4C9H9N3S3
N-(3-Methyl-iosothiazolyl-4)methyl-guanidine hemi-sulfate chemical structure, C12H22N8O4S3, CAS 40064-56-0
N-(3-Methyl-iosothiazolyl-4)methyl-guanidine hemi-sulfate
CAS 40064-56-0C12H22N8O4S3
Isothiazole, 4,5-dichloro-3-(trichloromethyl)- chemical structure, C4Cl5NS, CAS 118888-36-1
Isothiazole, 4,5-dichloro-3-(trichloromethyl)-
CAS 118888-36-1C4Cl5NS
3-Ethyl 5-methyl 4-aminoisothiazole-3,5-dicarboxylate chemical structure, C8H10N2O4S, CAS 632291-73-7
3-Ethyl 5-methyl 4-aminoisothiazole-3,5-dicarboxylate
CAS 632291-73-7C8H10N2O4S
5-Methyl-3-(methylsulfonyl)-4-isothiazolecarbonitrile chemical structure, C6H6N2O2S2, CAS 82000-51-9
5-Methyl-3-(methylsulfonyl)-4-isothiazolecarbonitrile
CAS 82000-51-9C6H6N2O2S2
3-Chloro-5-[(2-cyanoethyl)(methyl)amino]-4-isothiazolecarbonitrile chemical structure, C8H7ClN4S, CAS 866009-35-0
3-Chloro-5-[(2-cyanoethyl)(methyl)amino]-4-isothiazolecarbonitrile
CAS 866009-35-0C8H7ClN4S
5-Methyl-3-methylsulfanyl-1,2-thiazole-4-carboxylic acid chemical structure, C6H7NO2S2, CAS 338778-85-1
5-Methyl-3-methylsulfanyl-1,2-thiazole-4-carboxylic acid
CAS 338778-85-1C6H7NO2S2
3-Bromo-4-iodo-1,2-thiazole chemical structure, C3HBrINS, CAS 202287-54-5
3-Bromo-4-iodo-1,2-thiazole
CAS 202287-54-5C3HBrINS
5-Amino-3-chloro-1,2-thiazole-4-carbonitrile chemical structure, C4H2ClN3S, CAS 3889-68-7
5-Amino-3-chloro-1,2-thiazole-4-carbonitrile
CAS 3889-68-7C4H2ClN3S
2-[(4-Cyano-5-methyl-3-isothiazolyl)sulfanyl]acetohydrazide chemical structure, C7H8N4OS2, CAS 338395-68-9
2-[(4-Cyano-5-methyl-3-isothiazolyl)sulfanyl]acetohydrazide
CAS 338395-68-9C7H8N4OS2
4-Amino-3-isothiazolecarboxamide chemical structure, C4H5N3OS, CAS 4592-54-5
4-Amino-3-isothiazolecarboxamide
CAS 4592-54-5C4H5N3OS
3-Isothiazolecarboxylic acid, 4,5-dichloro-, heptadecyl ester chemical structure, C21H35Cl2NO2S, CAS 696649-34-0
3-Isothiazolecarboxylic acid, 4,5-dichloro-, heptadecyl ester
CAS 696649-34-0C21H35Cl2NO2S
3-Isothiazolecarboxylic acid, 4,5-dichloro-, pentadecyl ester chemical structure, C19H31Cl2NO2S, CAS 696649-38-4
3-Isothiazolecarboxylic acid, 4,5-dichloro-, pentadecyl ester
CAS 696649-38-4C19H31Cl2NO2S
3-Methyl-N-(2-methylpropyl)-1,2-thiazol-5-amine chemical structure, C8H14N2S, CAS 522597-14-4
3-Methyl-N-(2-methylpropyl)-1,2-thiazol-5-amine
CAS 522597-14-4C8H14N2S
Isothiazole, tribromo- chemical structure, C3Br3NS, CAS 71091-87-7
Isothiazole, tribromo-
CAS 71091-87-7C3Br3NS
4-Bromo-isothiazole chemical structure, C3H2BrNS, CAS 24340-77-0
4-Bromo-isothiazole
CAS 24340-77-0C3H2BrNS
Isothiazole-5-carboxylic acid chemical structure, C4H3NO2S, CAS 10271-85-9
Isothiazole-5-carboxylic acid
CAS 10271-85-9C4H3NO2S