CompoundList
Sign in
Murcko scaffold

Isothiazole scaffold

1,868 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
5
Chemicals
1,868
With full pages
279
Scaffold SMILES

c1cnsc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the Isothiazole page
Murcko scaffold c1cnsc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,825 to 1,868 of 1,868 chemicals

5-Amino-3-(difluoromethyl)-1,2-thiazole-4-carbonitrile chemical structure, C5H3F2N3S, CAS 2913245-23-3
5-Amino-3-(difluoromethyl)-1,2-thiazole-4-carbonitrile
CAS 2913245-23-3C5H3F2N3S
3-(Trifluoromethyl)-1,2-thiazol-4-amine hydrochloride chemical structure, C4H4ClF3N2S, CAS 2913278-99-4
3-(Trifluoromethyl)-1,2-thiazol-4-amine hydrochloride
CAS 2913278-99-4C4H4ClF3N2S
4-(Trifluoromethyl)-1,2-thiazole-5-carboxylic acid chemical structure, C5H2F3NO2S, CAS 2901095-57-4
4-(Trifluoromethyl)-1,2-thiazole-5-carboxylic acid
CAS 2901095-57-4C5H2F3NO2S
1-(3-Methyl-1,2-thiazol-4-yl)methanamine dihydrochloride chemical structure, C5H10Cl2N2S, CAS 2901099-22-5
1-(3-Methyl-1,2-thiazol-4-yl)methanamine dihydrochloride
CAS 2901099-22-5C5H10Cl2N2S
Ethyl 4-amino-5-iodo-1,2-thiazole-3-carboxylate chemical structure, C6H7IN2O2S, CAS 2913410-97-4
Ethyl 4-amino-5-iodo-1,2-thiazole-3-carboxylate
CAS 2913410-97-4C6H7IN2O2S
tert-Butyl 4-amino-5-iodo-1,2-thiazole-3-carboxylate chemical structure, C8H11IN2O2S, CAS 2913411-98-8
tert-Butyl 4-amino-5-iodo-1,2-thiazole-3-carboxylate
CAS 2913411-98-8C8H11IN2O2S
3-(2-Methoxyethoxy)-1,2-thiazole-5-carbaldehyde chemical structure, C7H9NO3S, CAS 2913403-83-3
3-(2-Methoxyethoxy)-1,2-thiazole-5-carbaldehyde
CAS 2913403-83-3C7H9NO3S
3-(Trifluoromethyl)-1,2-thiazol-5-amine hydrochloride chemical structure, C4H4ClF3N2S, CAS 2901066-98-4
3-(Trifluoromethyl)-1,2-thiazol-5-amine hydrochloride
CAS 2901066-98-4C4H4ClF3N2S
3-(Propan-2-yloxy)-1,2-thiazole-5-carbaldehyde chemical structure, C7H9NO2S, CAS 2901105-23-3
3-(Propan-2-yloxy)-1,2-thiazole-5-carbaldehyde
CAS 2901105-23-3C7H9NO2S
tert-Butyl N-[(3-methyl-1,2-thiazol-4-yl)methyl]carbamate chemical structure, C10H16N2O2S, CAS 2913403-11-7
tert-Butyl N-[(3-methyl-1,2-thiazol-4-yl)methyl]carbamate
CAS 2913403-11-7C10H16N2O2S
4-Bromo-3-ethoxy-1,2-thiazole chemical structure, C5H6BrNOS, CAS 2913268-20-7
4-Bromo-3-ethoxy-1,2-thiazole
CAS 2913268-20-7C5H6BrNOS
Sodium (4-bromo-3-methoxy-1,2-thiazol-5-yl)(hydroxy)methanesulfonate chemical structure, C5H5BrNNaO5S2, CAS 2105009-14-9
Sodium (4-bromo-3-methoxy-1,2-thiazol-5-yl)(hydroxy)methanesulfonate
CAS 2105009-14-9C5H5BrNNaO5S2
3-(Chloromethyl)-4-methyl-1,2-thiazole chemical structure, C5H6ClNS, CAS 2840831-46-9
3-(Chloromethyl)-4-methyl-1,2-thiazole
CAS 2840831-46-9C5H6ClNS
Ethyl 4-iodo-5-methylisothiazole-3-carboxylate chemical structure, C7H8INO2S, CAS 2924155-90-6
Ethyl 4-iodo-5-methylisothiazole-3-carboxylate
CAS 2924155-90-6C7H8INO2S
(1,2-Thiazol-3-yl)methanesulfonyl chloride chemical structure, C4H4ClNO2S2, CAS 2162745-61-9
(1,2-Thiazol-3-yl)methanesulfonyl chloride
CAS 2162745-61-9C4H4ClNO2S2
Ethyl 4-bromoisothiazole-5-carboxylate chemical structure, C6H6BrNO2S, CAS 2168896-84-0
Ethyl 4-bromoisothiazole-5-carboxylate
CAS 2168896-84-0C6H6BrNO2S
Methyl 5-bromo-4-[(2,2,2-trifluoroacetyl)amino]-3-isothiazolecarboxylate chemical structure, C7H4BrF3N2O3S, CAS 2180122-21-6
Methyl 5-bromo-4-[(2,2,2-trifluoroacetyl)amino]-3-isothiazolecarboxylate
CAS 2180122-21-6C7H4BrF3N2O3S
5-Neopentylisothiazol-3-amine chemical structure, C8H14N2S, CAS 2892670-44-7
5-Neopentylisothiazol-3-amine
CAS 2892670-44-7C8H14N2S
(E)-3-Methyl-5-(prop-1-en-1-yl)isothiazole-4-carboxylic acid chemical structure, C8H9NO2S, CAS 2924153-90-0
(E)-3-Methyl-5-(prop-1-en-1-yl)isothiazole-4-carboxylic acid
CAS 2924153-90-0C8H9NO2S
1-(4-Bromo-1,2-thiazol-5-yl)-2-chloroethan-1-one chemical structure, C5H3BrClNOS, CAS 2167590-05-6
1-(4-Bromo-1,2-thiazol-5-yl)-2-chloroethan-1-one
CAS 2167590-05-6C5H3BrClNOS
3-IsothiaZolemethanamine dihydrochloride chemical structure, C4H8Cl2N2S, CAS 2995276-24-7
3-IsothiaZolemethanamine dihydrochloride
CAS 2995276-24-7C4H8Cl2N2S
Methyl 5-bromo-3-chloroisothiazole-4-carboxylate chemical structure, C5H3BrClNO2S, CAS 2947425-56-9
Methyl 5-bromo-3-chloroisothiazole-4-carboxylate
CAS 2947425-56-9C5H3BrClNO2S
Methyl 4-(methylthio)isothiazole-3-carboxylate chemical structure, C6H7NO2S2, CAS 2794197-46-7
Methyl 4-(methylthio)isothiazole-3-carboxylate
CAS 2794197-46-7C6H7NO2S2
1-(3-Chloroisothiazol-5-yl)ethan-1-amine chemical structure, C5H7ClN2S, CAS 2838661-70-2
1-(3-Chloroisothiazol-5-yl)ethan-1-amine
CAS 2838661-70-2C5H7ClN2S