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Murcko scaffold

Isothiazole scaffold

1,868 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
5
Chemicals
1,868
With full pages
279
Scaffold SMILES

c1cnsc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the Isothiazole page
Murcko scaffold c1cnsc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 241 to 288 of 1,868 chemicals

1-(3,5-Dimethylisothiazol-4-yl)ethanol chemical structure, C7H11NOS, CAS 113234-34-7
1-(3,5-Dimethylisothiazol-4-yl)ethanol
CAS 113234-34-7C7H11NOS
(3,5-Dimethyl-1,2-thiazol-4-yl)acetonitrile chemical structure, C7H8N2S, CAS 117504-26-4
(3,5-Dimethyl-1,2-thiazol-4-yl)acetonitrile
CAS 117504-26-4C7H8N2S
3,5-Dimethyl-1,2-thiazole-4-carbaldehyde chemical structure, C6H7NOS, CAS 91367-85-0
3,5-Dimethyl-1,2-thiazole-4-carbaldehyde
CAS 91367-85-0C6H7NOS
(3,5-Dimethyl-1,2-thiazol-4-yl)methanol chemical structure, C6H9NOS, CAS 53064-43-0
(3,5-Dimethyl-1,2-thiazol-4-yl)methanol
CAS 53064-43-0C6H9NOS
4-(Chloromethyl)-3,5-dimethyl-1,2-thiazole chemical structure, C6H8ClNS, CAS 53064-44-1
4-(Chloromethyl)-3,5-dimethyl-1,2-thiazole
CAS 53064-44-1C6H8ClNS
1,2-Thiazole-3-carbaldehyde chemical structure, C4H3NOS, CAS 34490-97-6
1,2-Thiazole-3-carbaldehyde
CAS 34490-97-6C4H3NOS
3-Isothiazolecarboxamide,4-amino-N-methyl-(9CI) chemical structure, C5H7N3OS, CAS 115106-39-3
3-Isothiazolecarboxamide,4-amino-N-methyl-(9CI)
CAS 115106-39-3C5H7N3OS
1-(3,5-Dimethylisothiazol-4-yl)ethan-1-one chemical structure, C7H9NOS, CAS 23031-81-4
1-(3,5-Dimethylisothiazol-4-yl)ethan-1-one
CAS 23031-81-4C7H9NOS
1-(3,5-Dimethyl-1,2-thiazol-4-yl)propan-1-one chemical structure, C8H11NOS, CAS 120507-64-4
1-(3,5-Dimethyl-1,2-thiazol-4-yl)propan-1-one
CAS 120507-64-4C8H11NOS
2-Chloro-N-(3,5-dimethyl-1,2-thiazol-4-yl)-N-(ethoxymethyl)acetamide chemical structure, C10H15ClN2O2S, CAS 87675-15-8
2-Chloro-N-(3,5-dimethyl-1,2-thiazol-4-yl)-N-(ethoxymethyl)acetamide
CAS 87675-15-8C10H15ClN2O2S
2-Chloro-N-(3,5-dimethyl-1,2-thiazol-4-yl)-N-(prop-2-yn-1-yl)acetamide chemical structure, C10H11ClN2OS, CAS 87675-17-0
2-Chloro-N-(3,5-dimethyl-1,2-thiazol-4-yl)-N-(prop-2-yn-1-yl)acetamide
CAS 87675-17-0C10H11ClN2OS
3-Isopropylisothiazol-5-amine chemical structure, C6H10N2S, CAS 95882-25-0
3-Isopropylisothiazol-5-amine
CAS 95882-25-0C6H10N2S
3-Amino-5-(methylamino)isothiazole-4-carbonitrile chemical structure, C5H6N4S, CAS 117377-36-3
3-Amino-5-(methylamino)isothiazole-4-carbonitrile
CAS 117377-36-3C5H6N4S
Ethyl 3-amino-5-(methylamino)isothiazole-4-carboxylate chemical structure, C7H11N3O2S, CAS 117377-37-4
Ethyl 3-amino-5-(methylamino)isothiazole-4-carboxylate
CAS 117377-37-4C7H11N3O2S
3-Amino-5-(ethylamino)-1,2-thiazole-4-carbonitrile chemical structure, C6H8N4S, CAS 117377-38-5
3-Amino-5-(ethylamino)-1,2-thiazole-4-carbonitrile
CAS 117377-38-5C6H8N4S
3,5-Dimethyl-4-nitroisothiazole chemical structure, C5H6N2O2S, CAS 35611-00-8
3,5-Dimethyl-4-nitroisothiazole
CAS 35611-00-8C5H6N2O2S
Ethyl 3,5-dimethyl-1,2-thiazole-4-carboxylate chemical structure, C8H11NO2S, CAS 120586-33-6
Ethyl 3,5-dimethyl-1,2-thiazole-4-carboxylate
CAS 120586-33-6C8H11NO2S
3,5-Dimethoxy-1,2-thiazole chemical structure, C5H7NO2S, CAS 119224-68-9
3,5-Dimethoxy-1,2-thiazole
CAS 119224-68-9C5H7NO2S
4-Bromo-3,5-dimethoxy-1,2-thiazole chemical structure, C5H6BrNO2S, CAS 119224-70-3
4-Bromo-3,5-dimethoxy-1,2-thiazole
CAS 119224-70-3C5H6BrNO2S
5-Bromo-3-methyl-4-isothiazolesulfonyl chloride chemical structure, C4H3BrClNO2S2, CAS 111923-80-9
5-Bromo-3-methyl-4-isothiazolesulfonyl chloride
CAS 111923-80-9C4H3BrClNO2S2
(3-Methyl-1,2-thiazol-5-yl)methanol chemical structure, C5H7NOS, CAS 17265-60-0
(3-Methyl-1,2-thiazol-5-yl)methanol
CAS 17265-60-0C5H7NOS
5-Bromo-3-methyl-isothiazole-4-sulfonic acid chemical structure, C4H4BrNO3S2, CAS 111923-79-6
5-Bromo-3-methyl-isothiazole-4-sulfonic acid
CAS 111923-79-6C4H4BrNO3S2
3-Chloro-5-methyl-1,2-thiazole chemical structure, C4H4ClNS, CAS 14217-67-5
3-Chloro-5-methyl-1,2-thiazole
CAS 14217-67-5C4H4ClNS
4-Isothiazolesulfonyl chloride, 3-methyl-5-(2,2,2-trifluoroethoxy)- chemical structure, C6H5ClF3NO3S2, CAS 111923-86-5
4-Isothiazolesulfonyl chloride, 3-methyl-5-(2,2,2-trifluoroethoxy)-
CAS 111923-86-5C6H5ClF3NO3S2