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Murcko scaffold

3-Phenylethynyl-pyridine scaffold

65 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
65
With full pages
3
Scaffold SMILES

C(#Cc1cccnc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Phenylethynyl-pyridine page
Murcko scaffold C(#Cc1cccnc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 65 chemicals

Ethyl 5-(2-phenyleth-1-ynyl)nicotinate chemical structure, C16H13NO2, CAS 175203-65-3
Ethyl 5-(2-phenyleth-1-ynyl)nicotinate
CAS 175203-65-3C16H13NO2
5-(2-Phenyleth-1-ynyl)nicotinic acid chemical structure, C14H9NO2, CAS 175203-69-7
5-(2-Phenyleth-1-ynyl)nicotinic acid
CAS 175203-69-7C14H9NO2
5-(2-Phenylethynyl)nicotinonitrile chemical structure, C14H8N2, CAS 845266-26-4
5-(2-Phenylethynyl)nicotinonitrile
CAS 845266-26-4C14H8N2
3-Phenylethynyl-pyridine chemical structure, C13H9N, CAS 13238-38-5
3-Phenylethynyl-pyridine
CAS 13238-38-5C13H9N
3-(4-Methoxy-phenyl-1-ethynyl)-pyridine chemical structure, C14H11NO, CAS 817574-43-9
3-(4-Methoxy-phenyl-1-ethynyl)-pyridine
CAS 817574-43-9C14H11NO
Pyridine, 3-[(4-methylphenyl)ethynyl]- chemical structure, C14H11N, CAS 733035-88-6
Pyridine, 3-[(4-methylphenyl)ethynyl]-
CAS 733035-88-6C14H11N
2-Chloro-5-(phenylethynyl)pyridine chemical structure, C13H8ClN, CAS 87148-60-5
2-Chloro-5-(phenylethynyl)pyridine
CAS 87148-60-5C13H8ClN
Benzenamine, 2-(3-pyridinylethynyl)- chemical structure, C13H10N2, CAS 124643-40-9
Benzenamine, 2-(3-pyridinylethynyl)-
CAS 124643-40-9C13H10N2
Benzaldehyde, 4-[(5-bromo-3-pyridinyl)ethynyl]- chemical structure, C14H8BrNO, CAS 650606-56-7
Benzaldehyde, 4-[(5-bromo-3-pyridinyl)ethynyl]-
CAS 650606-56-7C14H8BrNO
2-Chloro-3-(2-phenylethynyl)pyridine chemical structure, C13H8ClN, CAS 111079-39-1
2-Chloro-3-(2-phenylethynyl)pyridine
CAS 111079-39-1C13H8ClN
3-(2-Phenylethynyl)-4-pyridinecarboxaldehyde chemical structure, C14H9NO, CAS 222167-48-8
3-(2-Phenylethynyl)-4-pyridinecarboxaldehyde
CAS 222167-48-8C14H9NO
5-Bromo-3-(phenylethynyl)pyridin-2-amine chemical structure, C13H9BrN2, CAS 953414-71-6
5-Bromo-3-(phenylethynyl)pyridin-2-amine
CAS 953414-71-6C13H9BrN2
5-Phenylethynyl-pyridin-2-ylamine chemical structure, C13H10N2, CAS 94920-96-4
5-Phenylethynyl-pyridin-2-ylamine
CAS 94920-96-4C13H10N2
2-Pyridinecarbonitrile, 6-chloro-3-[2-[4-(dimethylamino)phenyl]ethynyl]- chemical structure, C16H12ClN3, CAS 1276688-39-1
2-Pyridinecarbonitrile, 6-chloro-3-[2-[4-(dimethylamino)phenyl]ethynyl]-
CAS 1276688-39-1C16H12ClN3
5-((3-Fluorophenyl)ethynyl)picolinic acid chemical structure, C14H8FNO2, CAS 1403771-21-0
5-((3-Fluorophenyl)ethynyl)picolinic acid
CAS 1403771-21-0C14H8FNO2
5-[2-(3-Fluorophenyl)ethynyl]-N-[(2R)-3-hydroxy-3-methylbutan-2-yl]pyridine-2-carboxamide chemical structure, C19H19FN2O2, CAS 1428630-85-6
5-[2-(3-Fluorophenyl)ethynyl]-N-[(2R)-3-hydroxy-3-methylbutan-2-yl]pyridine-2-carboxamide
CAS 1428630-85-6C19H19FN2O2
5-[2-(3-Fluorophenyl)ethynyl]-N-(2-hydroxy-1,1-dimethylethyl)-2-pyridinecarboxamide chemical structure, C18H17FN2O2, CAS 1428630-88-9
5-[2-(3-Fluorophenyl)ethynyl]-N-(2-hydroxy-1,1-dimethylethyl)-2-pyridinecarboxamide
CAS 1428630-88-9C18H17FN2O2
3-Fluoro-5-(phenylethynyl)pyridin-2-amine chemical structure, C13H9FN2, CAS 1686186-44-6
3-Fluoro-5-(phenylethynyl)pyridin-2-amine
CAS 1686186-44-6C13H9FN2
4-Methyl-3-[2-(3-pyridinyl)ethynyl]benzoic acid chemical structure, C15H11NO2, CAS 1388805-31-9
4-Methyl-3-[2-(3-pyridinyl)ethynyl]benzoic acid
CAS 1388805-31-9C15H11NO2
3-Chloro-5-[2-(4-methoxy-2-methylphenyl)ethynyl]-2-pyridinecarbonitrile chemical structure, C16H11ClN2O, CAS 1186637-69-3
3-Chloro-5-[2-(4-methoxy-2-methylphenyl)ethynyl]-2-pyridinecarbonitrile
CAS 1186637-69-3C16H11ClN2O
tert-Butyl{4-chloro-2-[(2-methylpyridin-3-yl)ethynyl]phenoxy}acetate chemical structure, C20H20ClNO3, CAS 1240286-92-3
tert-Butyl{4-chloro-2-[(2-methylpyridin-3-yl)ethynyl]phenoxy}acetate
CAS 1240286-92-3C20H20ClNO3
tert-Butyl[(5-chloro-3-{[3-(propylsulfonyl)phenyl]ethynyl}pyridin-2-yl)oxy]acetate chemical structure, C22H24ClNO5S, CAS 1240288-30-5
tert-Butyl[(5-chloro-3-{[3-(propylsulfonyl)phenyl]ethynyl}pyridin-2-yl)oxy]acetate
CAS 1240288-30-5C22H24ClNO5S
tert-Butyl{4-chloro-2-[(4-methylpyridin-3-yl)ethynyl]phenoxy}acetate chemical structure, C20H20ClNO3, CAS 1240286-89-8
tert-Butyl{4-chloro-2-[(4-methylpyridin-3-yl)ethynyl]phenoxy}acetate
CAS 1240286-89-8C20H20ClNO3
tert-Butyl{4-chloro-2-[(4-propylpyridin-3-yl)ethynyl]phenoxy}acetate chemical structure, C22H24ClNO3, CAS 1240287-13-1
tert-Butyl{4-chloro-2-[(4-propylpyridin-3-yl)ethynyl]phenoxy}acetate
CAS 1240287-13-1C22H24ClNO3