Murcko scaffold
Methylenedinaphthalene scaffold
147 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 21
- Chemicals
- 147
- With full pages
- 15
Scaffold SMILES
c1ccc2c(Cc3cccc4ccccc34)cccc2c1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 147 chemicals
Pamoic acid
CAS 130-85-8C23H16O6
2-Naphthalenecarboxylic acid, 4,4'-methylenebis(3-hydroxy-, compd. with N1,N1-diethyl-N4-(6-methoxy-8-quinolinyl)-1,4-pentanediamine (1:1)
CAS 635-05-2C42H45N3O7
1,1'-Methylenebis(2-naphthalenol)
CAS 1096-84-0C21H16O2
Clamoxyquin pamoate
CAS 2923-09-3C40H40ClN3O7
Chlorcyclizine pamoate
CAS 10450-53-0C41H37ClN2O6
Imipramine pamoate
CAS 10075-24-8C61H64N4O6
Hydroxyzine pamoate
CAS 10246-75-0C44H43ClN2O8
1-Naphthaleneacetic acid, alpha-(1-naphthyl)-, 2-(diethylamino)ethyl ester, hydrochloride
CAS 63905-78-2C28H30ClNO2
4,4'-Methylenebis(3-hydroxynaphthalene-2-carboxylic acid)--N~1~,N~1~-diethyl-N~4~-(6-methoxy-1,2,3,4-tetrahydroquinolin-8-yl)pentane-1,4-diamine (1/1)
CAS 63979-16-8C42H49N3O7
1,3-Naphthalenediol, 4,4'-methylenedi-
CAS 68828-44-4C21H16O4
2,7-Naphthalenediol, 1,1'-methylenedi-
CAS 68828-45-5C21H16O4
1,3-Naphthalenediol, 4,4'-methylenedi-, tetraacetate
CAS 68828-48-8C29H24O8
2-Naphthoic acid, 4,4'-methylenebis(3-acetoxy-
CAS 68828-51-3C27H20O8
4,4'-Methylenebis(3-hydroxy-2-naphthoic) acid, compound with 1,1-dimethylbiguanide (1:2)
CAS 34461-22-8C31H38N10O6
Trimethoprim pamoate
CAS 66934-68-7C37H34N4O9
2-Naphthalenesulfonic acid, 1,1'-methylenebis-
CAS 84-90-2C21H16O6S2
2-Naphthalenesulfonic acid, 1,1'-methylenebis-, sodium salt (1:2)
CAS 2379-92-2C21H14Na2O6S2
![2-Methoxy-1-[(2-methoxynaphthalen-1-yl)methyl]naphthalene chemical structure, C23H20O2, CAS 2212-45-5](/s/WOAKPXSTZYSSEU-UHFFFAOYSA-N.svg)
2-Methoxy-1-[(2-methoxynaphthalen-1-yl)methyl]naphthalene
CAS 2212-45-5C23H20O2
2-Naphthalenol, 1-((2-methoxy-1-naphthalenyl)methyl)-
CAS 33230-77-2C22H18O2
2-Naphthalenol, 1,1'-methylenebis-, diacetate
CAS 60964-81-0C25H20O4
Glycolic acid, dinaphthyl-, 2-(diethylamino)ethyl ester, hydrochloride
CAS 63938-43-2C28H30ClNO3
Naphthalenesulfonic acid, methylenebis-
CAS 25377-91-7C21H16O6S2
Clorprenaline pamoate
CAS 82178-30-1C34H32ClNO7
Pyrimethamine pamoate
CAS 85819-86-9C35H29ClN4O6
- 2,4-Pyridinediamine, 5-(4-chlorophenyl)-6-ethyl-, 4,4'-methylenebis(3-hydroxy-2-naphthalenecarboxylate) (2:1)96283-37-3C47H42Cl2N8O6
- Sulfamethoxazole pamoate100345-21-9C33H27N3O9S
- Benzenamine, 4,4'-sulfonylbis-, 4,4'-methylenebis(3-hydroxy-2-naphthalenecarboxylate) (1:1)106776-92-5C35H28N2O8S
- Ampicillin embonate119229-01-5C55H54N6O14S2
- 4,4'-Methylenebis(3-hydroxynaphthalene-2-carboxylic acid)--2-(diethylamino)-1-(6-methoxyquinolin-4-yl)ethan-1-ol (1/1)5423-42-7C39H38N2O8
- 4-[(3-Carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid, N',N'-dibutyl-N-[(4-chlorophenyl)-(4-methoxyphenyl)methyl]ethane-1,2-diamine6279-76-1C47H51ClN2O7
- 4-[(3-Carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid, N',N'-dibutyl-N-[(4-chlorophenyl)-(4-methoxyphenyl)methyl]propane-1,3-diamine6288-45-5C48H53ClN2O7
- 4,4'-Methylenebis(3-hydroxynaphthalene-2-carboxylic acid)--2-chloro-4-{[4-(diethylamino)phenyl]methyl}-N,N-dimethylaniline (1/1)5427-70-3C42H41ClN2O6
- 4-[(3-Carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid, 4-N-(6-chloro-3-methylquinolin-4-yl)-1-N,1-N-diethylpentane-1,4-diamine5427-71-4C42H44ClN3O6
- 4,4'-Methylenebis(3-hydroxynaphthalene-2-carboxylic acid)--2-chloro-4-{[2-(diethylamino)-5-methoxyphenyl]methyl}-N,N-dimethylaniline (1/1)5427-73-6C43H43ClN2O7
- 4,4'-Methylenebis(3-hydroxynaphthalene-2-carboxylic acid)--2-chloro-4-{[4-(dipropylamino)phenyl]methyl}-N,N-dimethylaniline (1/1)5427-75-8C44H45ClN2O6
- 4,4'-Methylenebis(3-hydroxynaphthalene-2-carboxylic acid)--2-chloro-4-{[4-(dibutylamino)phenyl]methyl}-N,N-dimethylaniline (1/1)5427-77-0C46H49ClN2O6
- 1-(Bromo(1-naphthyl)methyl)naphthalene5467-20-9C21H15Br
- 1,1'-Methylenebis(4-methoxynaphthalene)2388-43-4C23H20O2
- 1-[[2-(Methylideneamino)naphthalen-1-yl]methyl]naphthalen-2-ol6341-74-8C22H17NO
- Ethyl 2-cyano-3,3-DI(1-naphthyl)propionate62875-52-9C26H21NO2
- 1-[(2-Amino-1-naphthalenyl)methyl]-2-naphthalenol28306-30-1C21H17NO
- 3,3-Dinaphthalen-1-ylpropanoic acid7499-41-4C23H18O2
- Diethyl 2-(dinaphthalen-1-ylmethyl)propanedioate7597-92-4C28H26O4
- 2-(Dinaphthalen-1-ylmethyl)propane-1,3-diol7495-56-9C24H22O2
- 3-(Dinaphthalen-1-ylmethyl)pentanedinitrile7504-41-8C26H20N2
- 2-Naphthalenecarboxylic acid, 4,4'-methylenebis(1-hydroxy-1175-41-3C23H16O6
- Methylenedinaphthalene28515-57-3C21H16
- Di-1-naphthylmethanol62784-66-1C21H16O
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(c1cccc2ccccc12)c1cccc2ccccc122 chemicals
c1ccc2c(c1)CCNC2Cc1cccc2ccccc122 chemicals
C1=CC(=Cc2ccnc3ccccc23)c2ccccc2N12 chemicals
c1cc(Cc2cccc3ncccc23)c2cccnc2c12 chemicals
c1ccc2c(Sc3cccc4ccccc34)cccc2c12 chemicals
c1cc2c(c(Nc3ccnc4ccccc34)c1)CCCC22 chemicals
O=S(=O)(c1cccc2ccccc12)c1cccc2ccccc121 chemical
c1ccc2c(Oc3cccc4ccccc34)cccc2c11 chemical
c1ccc2c(Nc3ncnc4ccccc34)cccc2c11 chemical
O=C(c1cccc2ccccc12)N1CCCc2ccccc211 chemical
O=c1cc(Nc2cccc3ccccc23)c2ccccc2o11 chemical![Scaffold c1ccc2c(C[n+]3cccc4ccccc43)cccc2c1](/scaffold/LBLMSLFZKCAHRB-UHFFFAOYSA-N/structure.svg)
c1ccc2c(C[n+]3cccc4ccccc43)cccc2c11 chemical