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Murcko scaffold

Ring system with 4 rings and 20 atoms

187 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
187
With full pages
3
Scaffold SMILES

c1ccc(C2CC(c3ccc4c(c3)OCO4)CN2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(C2CC(c3ccc4c(c3)OCO4)CN2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 187 chemicals

Atrasentan chemical structure, C29H38N2O6, CAS 173937-91-2
Atrasentan
CAS 173937-91-2C29H38N2O6
Atrasentan hydrochloride chemical structure, C29H39ClN2O6, CAS 195733-43-8
Atrasentan hydrochloride
CAS 195733-43-8C29H39ClN2O6
(2S,3S,4R)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid chemical structure, C29H38N2O6, CAS 173864-34-1
(2S,3S,4R)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid
CAS 173864-34-1C29H38N2O6
Atrasentan impurity 201 chemical structure, C29H38N2O6, CAS 1797510-53-2
Atrasentan impurity 201
CAS 1797510-53-2C29H38N2O6
4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid chemical structure, C29H38N2O6, CAS 2469258-87-3
4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid
CAS 2469258-87-3C29H38N2O6
3M7QW42Gdh chemical structure, C25H30N2O6, CAS 1140617-21-5
3M7QW42Gdh
CAS 1140617-21-5C25H30N2O6
Atrasentan impurity 30 chemical structure, C27H34N2O6, CAS 1058393-07-9
Atrasentan impurity 30
CAS 1058393-07-9C27H34N2O6
Atrasentan impurity 131 chemical structure, C32H44N2O6, CAS 1058349-04-4
Atrasentan impurity 131
CAS 1058349-04-4C32H44N2O6
Atrasentan impurity 41 chemical structure, C30H40N2O6, CAS 178738-93-7
Atrasentan impurity 41
CAS 178738-93-7C30H40N2O6
Atrasentan impurity 40 chemical structure, C30H40N2O6, CAS 178738-92-6
Atrasentan impurity 40
CAS 178738-92-6C30H40N2O6
Atrasentan impurity 116 chemical structure, C31H43N3O6, CAS 220584-55-4
Atrasentan impurity 116
CAS 220584-55-4C31H43N3O6
Atrasentan impurity 39 chemical structure, C30H40N2O6, CAS 178738-91-5
Atrasentan impurity 39
CAS 178738-91-5C30H40N2O6
Atrasentan impurity 162 chemical structure, C29H39N3O6, CAS 1063836-10-1
Atrasentan impurity 162
CAS 1063836-10-1C29H39N3O6
Atrasentan impurity 23 chemical structure, C27H34N2O6, CAS 1058393-35-3
Atrasentan impurity 23
CAS 1058393-35-3C27H34N2O6
Atrasentan impurity 38 chemical structure, C30H40N2O6, CAS 178607-92-6
Atrasentan impurity 38
CAS 178607-92-6C30H40N2O6
Atrasentan impurity 34 chemical structure, C26H32N2O6, CAS 1058392-78-1
Atrasentan impurity 34
CAS 1058392-78-1C26H32N2O6
Atrasentan impurity 29 chemical structure, C25H30N2O6, CAS 1058392-69-0
Atrasentan impurity 29
CAS 1058392-69-0C25H30N2O6
Atrasentan impurity 120 chemical structure, C30H40N2O7, CAS 474010-47-4
Atrasentan impurity 120
CAS 474010-47-4C30H40N2O7
(2R)-1-[(Dibutylcarbamoyl)methyl]-2beta-(4-methoxyphenyl)-4beta-(1,3-benzodioxole-5-yl)pyrrolidine-3alpha-carboxylic acid ethyl ester chemical structure, C31H42N2O6, CAS 195708-08-8
(2R)-1-[(Dibutylcarbamoyl)methyl]-2beta-(4-methoxyphenyl)-4beta-(1,3-benzodioxole-5-yl)pyrrolidine-3alpha-carboxylic acid ethyl ester
CAS 195708-08-8C31H42N2O6
(2S,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid chemical structure, C29H38N2O6, CAS 173937-92-3
(2S,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid
CAS 173937-92-3C29H38N2O6
1,3-Pyrrolidinedicarboxylic acid, 4-(1,3-benzodioxol-5-yl)-2-(4-methoxyphenyl)-, 1-(1,1-dimethylethyl) 3-ethyl ester, (2R,3R,4S)-rel- chemical structure, C26H31NO7, CAS 209214-29-9
1,3-Pyrrolidinedicarboxylic acid, 4-(1,3-benzodioxol-5-yl)-2-(4-methoxyphenyl)-, 1-(1,1-dimethylethyl) 3-ethyl ester, (2R,3R,4S)-rel-
CAS 209214-29-9C26H31NO7
(2R,3R,4S)-4-(Benzo[d][1,3]dioxol-5-yl)-1-(tert-butoxycarbonyl)-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid chemical structure, C24H27NO7, CAS 173864-48-7
(2R,3R,4S)-4-(Benzo[d][1,3]dioxol-5-yl)-1-(tert-butoxycarbonyl)-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid
CAS 173864-48-7C24H27NO7
Ethyl 4-(Benzo[d][1,3]dioxol-5-yl)-2-(4-methoxyphenyl)pyrrolidine-3-carboxylate chemical structure, C21H23NO5, CAS 173864-47-6
Ethyl 4-(Benzo[d][1,3]dioxol-5-yl)-2-(4-methoxyphenyl)pyrrolidine-3-carboxylate
CAS 173864-47-6C21H23NO5
Ethyl (2R,3R,4S)-4-(benzo[d][1,3]dioxol-5-yl)-2-(4-methoxyphenyl)pyrrolidine-3-carboxylate chemical structure, C21H23NO5, CAS 178739-03-2
Ethyl (2R,3R,4S)-4-(benzo[d][1,3]dioxol-5-yl)-2-(4-methoxyphenyl)pyrrolidine-3-carboxylate
CAS 178739-03-2C21H23NO5