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Murcko scaffold

5-(Pyrrolidin-3-yl)-1,2,4-oxadiazole scaffold

35 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
35
With full pages
5
Scaffold SMILES

c1noc(C2CCNC2)n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-(Pyrrolidin-3-yl)-1,2,4-oxadiazole page
Murcko scaffold c1noc(C2CCNC2)n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 35 of 35 chemicals

3-Methyl-5-(1-methylpyrrolidin-3-yl)-1,2,4-oxadiazole chemical structure, C8H13N3O, CAS 114724-47-9
3-Methyl-5-(1-methylpyrrolidin-3-yl)-1,2,4-oxadiazole
CAS 114724-47-9C8H13N3O
5-Pyrrolidin-3-yl-1,2,4-oxadiazol-3-amine chemical structure, C6H10N4O, CAS 114724-78-6
5-Pyrrolidin-3-yl-1,2,4-oxadiazol-3-amine
CAS 114724-78-6C6H10N4O
5-(1-Methylpyrrolidin-3-yl)-1,2,4-oxadiazol-3-amine chemical structure, C7H12N4O, CAS 114724-44-6
5-(1-Methylpyrrolidin-3-yl)-1,2,4-oxadiazol-3-amine
CAS 114724-44-6C7H12N4O
3-Ethyl-5-(1-methyl-3-pyrrolidinyl)-1,2,4-oxadiazole chemical structure, C9H15N3O, CAS 114724-48-0
3-Ethyl-5-(1-methyl-3-pyrrolidinyl)-1,2,4-oxadiazole
CAS 114724-48-0C9H15N3O
(r)-3-Methyl-5-(pyrrolidin-3-yl)-1,2,4-oxadiazole chemical structure, C7H11N3O, CAS 1243307-69-8
(r)-3-Methyl-5-(pyrrolidin-3-yl)-1,2,4-oxadiazole
CAS 1243307-69-8C7H11N3O
(s)-3-Methyl-5-(pyrrolidin-3-yl)-1,2,4-oxadiazole chemical structure, C7H11N3O, CAS 1243307-68-7
(s)-3-Methyl-5-(pyrrolidin-3-yl)-1,2,4-oxadiazole
CAS 1243307-68-7C7H11N3O
3-Methyl-5-(pyrrolidin-3-yl)-1,2,4-oxadiazole chemical structure, C7H11N3O, CAS 902836-46-8
3-Methyl-5-(pyrrolidin-3-yl)-1,2,4-oxadiazole
CAS 902836-46-8C7H11N3O
tert-Butyl 3-(3-methyl-1,2,4-oxadiazol-5-yl)pyrrolidine-1-carboxylate chemical structure, C12H19N3O3, CAS 1121057-53-1
tert-Butyl 3-(3-methyl-1,2,4-oxadiazol-5-yl)pyrrolidine-1-carboxylate
CAS 1121057-53-1C12H19N3O3
3-Methyl-5-(pyrrolidin-3-yl)-1,2,4-oxadiazole hydrochloride chemical structure, C7H12ClN3O, CAS 1121057-52-0
3-Methyl-5-(pyrrolidin-3-yl)-1,2,4-oxadiazole hydrochloride
CAS 1121057-52-0C7H12ClN3O
5-(Pyrrolidin-3-yl)-1,2,4-oxadiazole chemical structure, C6H9N3O, CAS 1211529-68-8
5-(Pyrrolidin-3-yl)-1,2,4-oxadiazole
CAS 1211529-68-8C6H9N3O
3-Ethyl-5-(pyrrolidin-3-yl)-1,2,4-oxadiazole chemical structure, C8H13N3O, CAS 1339103-05-7
3-Ethyl-5-(pyrrolidin-3-yl)-1,2,4-oxadiazole
CAS 1339103-05-7C8H13N3O
3-Methyl-5-[3-(trifluoromethyl)pyrrolidin-3-yl]-1,2,4-oxadiazole chemical structure, C8H10F3N3O, CAS 1342629-58-6
3-Methyl-5-[3-(trifluoromethyl)pyrrolidin-3-yl]-1,2,4-oxadiazole
CAS 1342629-58-6C8H10F3N3O
3-(3-Methyl-1,2,4-oxadiazol-5-yl)pyrrolidin-3-ol hydrochloride chemical structure, C7H12ClN3O2, CAS 1803606-38-3
3-(3-Methyl-1,2,4-oxadiazol-5-yl)pyrrolidin-3-ol hydrochloride
CAS 1803606-38-3C7H12ClN3O2
3-(3-Methyl-1,2,4-oxadiazol-5-yl)-3-pyrrolidinol chemical structure, C7H11N3O2, CAS 1697013-05-0
3-(3-Methyl-1,2,4-oxadiazol-5-yl)-3-pyrrolidinol
CAS 1697013-05-0C7H11N3O2
3-(3-Ethyl-1,2,4-oxadiazol-5-yl)pyrrolidin-3-ol hydrochloride chemical structure, C8H14ClN3O2, CAS 1803606-50-9
3-(3-Ethyl-1,2,4-oxadiazol-5-yl)pyrrolidin-3-ol hydrochloride
CAS 1803606-50-9C8H14ClN3O2
3-(3-Ethyl-1,2,4-oxadiazol-5-yl)pyrrolidin-3-ol chemical structure, C8H13N3O2, CAS 1702395-73-0
3-(3-Ethyl-1,2,4-oxadiazol-5-yl)pyrrolidin-3-ol
CAS 1702395-73-0C8H13N3O2
3-[3-(Propan-2-yl)-1,2,4-oxadiazol-5-yl]pyrrolidin-3-ol hydrochloride chemical structure, C9H16ClN3O2, CAS 1803586-91-5
3-[3-(Propan-2-yl)-1,2,4-oxadiazol-5-yl]pyrrolidin-3-ol hydrochloride
CAS 1803586-91-5C9H16ClN3O2
5-(1-Methylpyrrolidin-3-yl)-1,2,4-oxadiazole-3-carboxylic acid chemical structure, C8H11N3O3, CAS 1894728-38-1
5-(1-Methylpyrrolidin-3-yl)-1,2,4-oxadiazole-3-carboxylic acid
CAS 1894728-38-1C8H11N3O3
tert-Butyl 3-(3-(aminomethyl)-1,2,4-oxadiazol-5-yl)pyrrolidine-1-carboxylate chemical structure, C12H20N4O3, CAS 2098035-10-8
tert-Butyl 3-(3-(aminomethyl)-1,2,4-oxadiazol-5-yl)pyrrolidine-1-carboxylate
CAS 2098035-10-8C12H20N4O3
N-[3-(3-Methyl-1,2,4-oxadiazol-5-yl)pyrrolidin-3-yl]acetamide hydrochloride chemical structure, C9H15ClN4O2, CAS 1955553-11-3
N-[3-(3-Methyl-1,2,4-oxadiazol-5-yl)pyrrolidin-3-yl]acetamide hydrochloride
CAS 1955553-11-3C9H15ClN4O2
N-[3-(3-Methyl-1,2,4-oxadiazol-5-yl)pyrrolidin-3-yl]acetamide chemical structure, C9H14N4O2, CAS 1955541-23-7
N-[3-(3-Methyl-1,2,4-oxadiazol-5-yl)pyrrolidin-3-yl]acetamide
CAS 1955541-23-7C9H14N4O2
(3R,4R)-4-(3-Methyl-1,2,4-oxadiazol-5-yl)pyrrolidine-3-carboxamide chemical structure, C8H12N4O2, CAS 2165427-90-5
(3R,4R)-4-(3-Methyl-1,2,4-oxadiazol-5-yl)pyrrolidine-3-carboxamide
CAS 2165427-90-5C8H12N4O2
(R)-3-Methyl-5-(pyrrolidin-3-yl)-1,2,4-oxadiazole hydrochloride chemical structure, C7H12ClN3O, CAS 1867631-21-7
(R)-3-Methyl-5-(pyrrolidin-3-yl)-1,2,4-oxadiazole hydrochloride
CAS 1867631-21-7C7H12ClN3O
1-[3-(3-Methyl-1,2,4-oxadiazol-5-yl)pyrrolidin-1-yl]prop-2-en-1-one chemical structure, C10H13N3O2, CAS 2190141-78-5
1-[3-(3-Methyl-1,2,4-oxadiazol-5-yl)pyrrolidin-1-yl]prop-2-en-1-one
CAS 2190141-78-5C10H13N3O2